L Kynurenine Hydrolase (KYNU) (NM_001032998) Human Untagged Clone

CAT#: SC322236

KYNU (untagged)-Human kynureninase (KYNU), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KYNU
• Synonyms: KYNUU; VCRL2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322236 GGCCTGTACATTTTCAAGGAATTCTTGAGAGGTTCTTGGAGAGATTCTGGGAGCCAAACA
  CTCCATTGGGATCCTAGCTGTTTTAGAGAACAACTTGTAATGGAGCCTTCATCTCTTGAG
  CTGCCGGCTGACACAGTGCAGCGCATTGCGGCTGAACTCAAATGCCACCCAACGGATGAG
  AGGGTGGCTCTCCACCTAGATGAGGAAGATAAGCTGAGGCACTTCAGGGAGTGCTTTTAT
  ATTCCCAAAATACAGGATCTGCCTCCAGTTGATTTATCATTAGTGAATAAAGATGAAAAT
  GCCATCTATTTCTTGGGAAATTCTCTTGGCCTTCAACCAAAAATGGTTAAAACATATCTT
  GAAGAAGAACTAGATAAGTGGGCCAAAATAGCAGCCTATGGTCATGAAGTGGGGAAGCGT
  CCTTGGATTACAGGAGATGAGAGTATTGTAGGCCTTATGAAGGACATTGTAGGAGCCAAT
  GAGAAAGAAATAGCCCTAATGAATGCTTTGACTGTAAATTTACATCTTCTAATGTTATCA
  TTTTTTAAGCCTACGCCAAAACGATATAAAATTCTTCTAGAAGCCAAAGCCTTCCCTTCT
  GATCATTATGCTATTGAGTCACAACTACAACTTCACGGACTTAACATTGAAGAAAGTATG
  CGGATGATAAAGCCAAGAGAGGGGGAAGAAACCTTAAGAATAGAGGATATCCTTGAAGTA
  ATTGAGAAGGAAGGAGACTCAATTGCAGTGATCCTGTTCAGTGGGGTGCATTTTTACACT
  GGACAGCACTTTAATATTCCTGCCATCACAAAAGCTGGACAAGCGAAGGGTTGTTATGTT
  GGCTTTGATCTAGCACATGCAGTTGGAAATGTTGAACTCTACTTACATGACTGGGGAGTT
  GATTTTGCCTGCTGGTGTTCCTACAAGTATTTAAATGCAGGAGCAGGAGGAATTGCTGGT
  GCCTTCATTCATGAAAAGCATGCCCATACGATTAAACCTGCGAGATCGGAGTTCTTTAAT
  TAGGAATGGAATGCAACAGATTTGGACAAGTCAAGGACAAGAGCTTTAGAGAGACCAAAG
  AGTTTTTCACTGTTAAAGTGTCCAGTATGTAGCCGAGAACCATATGGAGAACATCAAATA
  CAGTGGAACAAATGTAACTGCTATTGATGTCACACTTTGTGAAGTAGTCTTTGTTGCTTA
  AAAAGGGTGACATCTAGTGGCTAAACATGTTATTTCAAATAAATAATATCGAAATAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322236 unedited
  GGCCATTGTATACGACTCCTATAGGGCGGCGCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATATCGTCGACCCACGCGTCCGGGCCTGTACATTTTCAAGGAATTCTT
  GAGAGGTTCTTGGAGAGATTCTGGGAGCCAAACACTCCATTGGGATCCTAGCTGTTTTAG
  AGAACAACTTGTAATGGAGCCTTCATCTCTTGAGCTGCCGGCTGACACAGTGCAGCGCAT
  TGCGGCTGAACTCAAATGCCACCCAACGGATGAGAGGGTGGCTCTCCACCTAGATGAGGA
  AGATAAGCTGAGGCACTTCAGGGAGTGCTTTTATATTCCCAAAATACAGGATCTGCCTCC
  AGTTGATTTATCAGGTGATGCTGCCAACTTACTGATTTAGTGTATGATGGTGTTTTTGAG
  GTGCTCCAGTGGCTTCTGTTTCTATCAGCTGTCCCTCCTGTTCAGCTACTGACGGGGTGG
  TGCGTAACGGCAAAAGCACCGCCGGACATCAGCGCTATCTCTGCTCTCACTGCCGTAAAA
  CATGGCAACTGCAGTTCACTTACACCGCTTCTCAACCCGGTACGCACCAGAAAATCATTG
  ATATGGCCATGAATGGCGTTGGATGCCGGGCAACAGCCCGCATTATGGGCGTTGGCCTCA
  ACACGATTTTACGTCACTTAAAAAACTCAGCCGCAGTCGGTAACCTCGCGCATACAGCCG
  GGCAGTGACGTCATCGTCTGCGCGGAAATGGACGACAGTGGGGCTATGTCGGGCTAAATC
  GCGCCAGCGCTGCTGTTTTACGCGTATGACGTCTCCGAAGAACGTTGTTGCGCCACGTAT
  CGGTGAACCCCACTTATGGCGACGCTGGGGCGTCTATGAGCTGCTTGTCACCCTTGACCT
  GGTGATATTGGATGAACGGATGGCTGACCCGCTGGA
• Restriction Sites: Please inquire
• ACCN: NM_001032998
• ORF Size: 924 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001032998.1, NP_001028170.1
• RefSeq Size: 1315
• RefSeq ORF: 924
• Locus ID: 8942
• Protein Families: Protease
• Protein Pathways: Metabolic pathways, Tryptophan metabolism
• Gene Summary: Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
  Transcript Variant: This variant (2) differs in the 5' UTR, 3' UTR and coding region compared to variant 3. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a.