Lipoprotein lipase (LPL) (NM_000237) Human Untagged Clone

CAT#: SC322258

LPL (untagged)-Human lipoprotein lipase (LPL)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LPL
• Synonyms: HDLCQ11; LIPD
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322258 GCTCAGCCGGCTCATCAGTCGGTCCGCGCCTTGCAGCTCCTCCAGAGGGACGCGCCCCGA
  GATGGAGAGCAAAGCCCTGCTCGTGCTGACTCTGGCCGTGTGGCTCCAGAGTCTGACCGC
  CTCCCGCGGAGGGGTGGCCGCCGCCGACCAAAGAAGAGATTTTATCGACATCGAAAGTAA
  ATTTGCCCTAAGGACCCCTGAAGACACAGCTGAGGACACTTGCCACCTCATTCCCGGAGT
  AGCAGAGTCCGTGGCTACCTGTCATTTCAATCACAGCAGCAAAACCTTCATGGTGATCCA
  TGGCTGGACGGTAACAGGAATGTATGAGAGTTGGGTGCCAAAACTTGTGGCCGCCCTGTA
  CAAGAGAGAACCAGACTCCAATGTCATTGTGGTGGACTGGCTGTCACGGGCTCAGGAGCA
  TTACCCAGTGTCCGCGGGCTACACCAAACTGGTGGGACAGGATGTGGCCCGGTTTATCAA
  CTGGATGGAGGAGGAGTTTAACTACCCTCTGGACAATGTCCATCTCTTGGGATACAGCCT
  TGGAGCCCATGCTGCTGGCATTGCAGGAAGTCTGACCAATAAGAAAGTCAACAGAATTAC
  TGGCCTCGATCCAGCTGGACCTAACTTTGAGTATGCAGAAGCCCCGAGTCGTCTTTCTCC
  TGATGATGCAGATTTTGTAGACGTCTTACACACATTCACCAGAGGGTCCCCTGGTCGAAG
  CATTGGAATCCAGAAACCAGTTGGGCATGTTGACATTTACCCGAATGGAGGTACTTTTCA
  GCCAGGATGTAACATTGGAGAAGCTATCCGCGTGATTGCAGAGAGAGGACTTGGAGATGT
  GGACCAGCTAGTGAAGTGCTCCCACGAGCGCTCCATTCATCTCTTCATCGACTCTCTGTT
  GAATGAAGAAAATCCAAGTAAGGCCTACAGGTGCAGTTCCAAGGAAGCCTTTGAGAAAGG
  GCTCTGCTTGAGTTGTAGAAAGAACCGCTGCAACAATCTGGGCTATGAGATCAGTAAAGT
  CAGAGCCAAAAGAAGCAGCAAAATGTACCTGAAGACTCGTTCTCAGATGCCCTACAAAGT
  CTTCCATTACCAAGTAAAGATTCATTTTTCTGGGACTGAGAGTGAAACCCATACCAATCA
  GGCCTTTGAGATTTCTCTGTATGGCACCGTGGCCGAGAGTGAGAACATCCCATTCACTCT
  GCCTGAAGTTTCCACAAATAAGACCTACTCCTTCCTAATTTACACAGAGGTAGATATTGG
  AGAACTACTCATGTTGAAGCTCAAATGGAAGAGTGATTCATACTTTAGCTGGTCAGACTG
  GTGGAGCAGTCCCGGCTTCGCCATTCAGAAGATCAGAGTAAAAGCAGGAGAGACTCAGAA
  AAAGGTGATCTTCTGTTCTAGGGAGAAAGTGTCTCATTTGCAGAAAGGAAAGGCACCTGC
  GGTATTTGTGAAATGCCATGACAAGTCTCTGAATAAGAAGTCAGGCTGAAACTGGGCGAA
  TCTACAGAACAAAGAACGGCATGTGAATTCTGTGAAGAATGAAGTGGAGGAAGTAACTTT
  TACAAAACATACCCAGTGTTTGGGGTGTTTCAAAAGTGGATTTTCCTGAATATTAATCCC
  AGCCCTACCCTTGTTAGTTATTTTAGGAGACAGTCTCAAGCACTAAAAAGTGGCTAATTC
  AATTTATGGGGTATAGTGGCCAAATAGCACATCCTCCAACGTTAAAAGACAGTGGATCAT
  GAAAAGTGCTGTTTTGTCCTTTGAGAAAGAAATAATTGTTTGAGCGCAGAGTAAAATAAG
  GCTCCTTCATGTGGCGTATTGGGCCATAGCCTATAATTGGTTAGAACCTCCTATTTTAAT
  TGGAATTCTGGATCTTTCGGACTGAGGCCTTCTCAAACTTTACTCTAAGTCTCCAAGAAT
  ACAGAAAATGCTTTTCCGCGGCACGAATCAGACTCATCTACACAGCAGTATGAATGATGT
  TTTAGAATGATTCCCTCTTGCTATTGGAATGTGGTCCAGACGTCAACCAGGAACATGTAA
  CTTGGAGAGGGACGAAGAAAGGGTCTGATAAACACAGAGGTTTTAAACAGTCCCTACCAT
  TGGCCTGCATCATGACAAAGTTACAAATTCAAGGAGATATAAAATCTAGATCAATTAATT
  CTTAATAGGCTTTATCGTTTATTGCTTAATCCCTCTCTCCCCCTTCTTTTTTGTCTCAAG
  ATTATATTATAATAATGTTCTCTGGGTAGGTGTTGAAAATGAGCCTGTAATCCTCAGCTG
  ACACATAATTTGAATGGTGCAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322258 unedited
  GGCGATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  CGCCTTGCAGCTCCTCCAGAGGGACGCGCCCCGAGATGGAGAGCAAAGCCCTGCTCGTGC
  TGACTCTGGCCGTGTGGCTCCAGAGTCTGACCGCCTCCCGCGGAGGGGTGGCCGCCGCCG
  ACCAAAGAAGAGATTTTATCGACATCGAAAGTAAATTTGCCCTAAGGACCCCTGAAGACA
  CAGCTGAGGACACTTGCCACCTCATTCCCGGAGTAGCAGAGTCCGTGGCTACCTGTCATT
  TCAATCACAGCAGCAAAACCTTCATGGTGATCCATGGCTGGACGGTAACAGGAATGTATG
  AGAGTTGGGTGCCAAAACTTGTGGCCGCCCTGTACAAGAGAGAACCAGACTCCAATGTCA
  TTGTGGTGGACTGGCTGTCACGGGCTCAGGAGCATTACCCAGTGTCCGCGGGCTACACCA
  AACTGGTGGGACAGGATGTGGCCCGGTTTATCAACTGGATGGAGGAGGAGTTTAACTACC
  CTCTGGACAATGTCCATCTCTTGGGATACAGCCTTGGAGCCCATGCTGCTGGCATTGCAG
  GAAGTCTGACCAATAAGAAAGTCAACAGAATTACTGGCCTCGATCCAGCTGGACCTAACT
  TTGAGTATGCAGAAGCCCCGAGTCGTCTTTCTCCTGATGATGCAGATTTTGTAGACGTCT
  TACACACATTCACCCAGAGGGTCCCCTGGTCGAAGCATTGGAATCCAGAAACCAGTTGGG
  CATGTTGACATTTACCCGAATGGAGGTACTTTTCAGCCAGGATGTAACATTGGAGAAGCT
  ATCCCGCGTGATGCAGAGAAGAGGACTTGAGATGTGGACCAGCTAGTGAGTGCCTCCCAC
  GAGGCGCTCCATTCCATCTTCTTTCATCGACTCTCTCTTGTTTGATGGAAGAAAAAATTC
  AAGGTTAG
• Restriction Sites: Please inquire
• ACCN: NM_000237
• ORF Size: 1428 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_000237.1, NP_000228.1
• RefSeq Size: 3549
• RefSeq ORF: 1428
• Locus ID: 4023
• Domains: lipase, PLAT
• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Glycerolipid metabolism, PPAR signaling pathway
• Gene Summary: LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]