DECR2 (NM_020664) Human Untagged Clone

CAT#: SC322397

DECR2 (untagged)-Human 2,4-dienoyl CoA reductase 2, peroxisomal (DECR2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DECR2
• Synonyms: PDCR; SDR17C1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322397 CCCGGTTCCAGGCGAGTTCGCAGCTGCGCGCCGGGTCCTGGAGGCCGAGGCCGCTCCCGC
  CCGTTGTCCCCGCAGTCCCCGACGGGAGCGCCATGGCCCAGCCGCCGCCCGACGTGGAGG
  GGGACGACTGTCTCCCCGCGTACCGCCACCTCTTCTGCCCGGACCTGCTGCGGGACAAAG
  TGGCCTTCATCACAGGAGGCGGCTCTGGGATTGGGTTCCGGATTGCTGAGATTTTCATGC
  GGCACGGCTGCCATACGGTGATTGCCAGTAGGAGCCTGCCGCGAGTGCTGACGGCCGCCA
  GGAAGCTGGCTGGGGCCACCGGCCGGCGCTGCCTCCCTCTCTCTATGGACGTCCGAGCGC
  CCCCAGCTGTCATGGCCGCCGTGGACCAGGCTCTGAAGGAGTTTGGCAGAATCGACATTC
  TCATTAACTGTGCGGCCGGGAACTTCCTGTGCCCCGCTGGCGCCTTGTCCTTCAACGCCT
  TCAAGACCGTGATGGACATCGATACCAGCGGCACCTTCAATGTGTCTCGTGTGCTCTATG
  AGAAGTTCTTCCGGGACCACGGAGGGGTGATCGTGAACATCACTGCCACCCTGGGGAACC
  GGGGGCAGGCGCTCCAGGTGCATGCAGGCTCCGCCAAGGCCGCTGTGGACGCGATGACGC
  GGCACTTGGCTGTGGAGTGGGGTCCCCAAAACATCCGCGTCAACAGCCTCGCCCCTGGCC
  CCATCAGTGGCACAGAGGGGCTCCGGCGACTGGGTGGCCCTCAAGCCAGCCTGAGCACCA
  AGGTCACTGCCAGCCCGCTGCAGAGGCTGGGGAACAAGACCGAGATCGCCCACAGCGTGC
  TCTACCTGGCCAGCCCTCTGGCTTCCTACGTGACGGGGGCCGTGCTGGTGGCCGATGGCG
  GGGCATGGTTGACGTTCCCAAACGGTGTCAAAGGGCTGCCGGATTTCGCATCCTTCTCTG
  CTAAGCTCTAGGAATCTTCCGGCCGCTGCTTCCTGCCGCCTCACTCAGCCAGGTGGAGAG
  CACCAATCTGAACCAGCAATGCCTGCAGCCCAGCCCCTCCTCTGAACACTCAGCTATTAC
  TGCGCTTTCCCTCCCCACGGCCCCAACTCCAGGGCAGGAGCAACTGGACAGTGGGCCTGG
  CCCGTGGAGCTGCCACGCAGGTGCCTGAGGGCCAGGTGCCACGCAGGTGTCTGAGGACCA
  GGTGCCACGCAGGTGGTGGGGGTACAGACAAGATGCTGGGATGTCCCCTGCCCCATGGTC
  AAGGGTGTCCTGCCTGCCTGGGTCCAGGGCCTGAGGGAGCCACATGGATCCCGAGACTTG
  TGTTCTCTTGGCTGAAAACACTGAGGTGCTCCCATCTGTGCGTGGCCCATGAGCTGGGAT
  GGTCCTCCAGCTGCCCACAAGGTCCGCCCCTCTGTCTCTGCACCACCTGTTTGCATAAAC
  ACACTTTGCTACAATCTTGCTAGTGCGTTTTCTTAAAAGATAATCTATTTACTGTAAAAA
  TAAATTGGACTTTGCAAAAGCTTTTAGAAGGAAAAGAAAGAGGATTAAAGAGAATTGCTG
  GTGATCCTAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322397 unedited
  TGCTCATTGTATACGACTCCTATAGGGCGGCTAGGCGATCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATATCGTCGACCCACGCGTCCGCCCGGTTCCAGGCGAGTTCGCAGCT
  GCGCGCCGGGTCCTGGAGGCCGAGGCCGCTCCCGCCCGTTGTCCCCGCAGTCCCCGACGG
  GAGCGCCATGGCCCAGCCGCCGCCCGACGTGGAGGGGGACGACTGTCTCCCCGCGTACCG
  CCACCTCTTCTGCCCGGACCTGCTGCGGGACAAAGTGGCCTTCATCACAGGAGGCGGCTC
  TGGGATTGGGTTCCGGATTGCTGAGATTTTCATGCGGCACGGCTGCCATACGGTGATTGC
  CAGTAGGAGCCTGCCGCGAGTGCTGACGGCCGCCAGGAAGCTGGCTGGGGCCACCGGCCG
  GCGCTGCCTCCCTCTCTCTATGGACGTCCGAGCGCCCCCAGCTGTCATGGCCGCCGTGGA
  CCAGGCTCTGAAGGAGTTTGGCAGAATCGACATTCTCATTAACTGTGCGGCCGGGAACTT
  CCTGTGCCCCGCTGGCGCCTTGTCCTTCAACGCCTTCAAGACCGTGATGGACATCGATAC
  CAGCGGCACCTTCAATGTGTCTCGTGTGCTCTATGAGAAGTTCTTCCGGGACCACGGAGG
  GGTGATCGTGAACATCACTGCCACCCTGGGGAACCGGGGGCAGGCGCTCCAGGTGCATGC
  AGGCTCCGCCAAGCCGCTGTGGACGCGATGACGCGGCACTTGGCTGTGGAGTGGGGGTCC
  CCAAAAACATCCGCGTCAACAGCCTCCGCCCCTGGCCCCATCAATGCACAGAGGGCTCCG
  CGACTGGGTGGCCCTCAAGCCAGCCTGACACAAGTCACTGCCAGCCCGCTGCAGAGCCTG
  GGACAAGACGAAATCGCCCACAAGCTGCTCTACCTGCAGGCCCTCTGCTTCTACTGACGG
  GGCCGTGGCCTTGGGTGGGC
• Restriction Sites: Please inquire
• ACCN: NM_020664
• ORF Size: 879 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020664.3, NP_065715.1
• RefSeq Size: 1599
• RefSeq ORF: 879
• Locus ID: 26063
• Domains: adh_short
• Protein Families: Druggable Genome
• Gene Summary: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. [UniProtKB/Swiss-Prot Function]