Tyrosyl tRNA synthetase (YARS) (NM_003680) Human Untagged Clone

CAT#: SC322455

YARS (untagged)-Human tyrosyl-tRNA synthetase (YARS)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: YARS
• Synonyms: CMTDIC; TYRRS; YRS; YTS
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322455 GGGGCTCTGGTGCCGGGCTGAGCGGGGGAAGCAGGGGTAGCGGAGCCATGGGGGACGCTC
  CCAGCCCTGAAGAGAAACTGCACCTTATCACCCGGAACCTGCAGGAGGTTCTGGGGGAAG
  AGAAGCTGAAGGAGATACTGAAGGAGCGGGAACTTAAAATTTACTGGGGAACGGCAACCA
  CGGGCAAACCACATGTGGCTTACTTTGTGCCCATGTCAAAGATTGCAGACTTCTTAAAGG
  CAGGGTGTGAGGTAACAATTCTGTTTGCGGACCTCCACGCATACCTGGATAACATGAAAG
  CCCCATGGGAACTTCTAGAACTCCGAGTCAGTTACTATGAGAATGTGATCAAAGCAATGC
  TGGAGAGCATTGGTGTGCCCTTGGAGAAGCTCAAGTTCATCAAAGGCACTGATTACCAGC
  TCAGCAAAGAGTACACACTAGATGTGTACAGACTCTCCTCCGTGGTCACACAGCACGATT
  CCAAGAAGGCTGGAGCTGAGGTGGTAAAGCAGGTGGAGCACCCTTTGCTGAGTGGCCTCT
  TATACCCCGGACTGCAGGCTTTGGATGAAGAGTATTTAAAAGTAGATGCCCAATTTGGAG
  GCATTGATCAGAGAAAGATTTTCACCTTTGCAGAGAAGTACCTCCCTGCACTTGGCTATT
  CAAAACGGGTCCATCTGATGAATCCTATGGTTCCAGGATTAACAGGCAGCAAAATGAGCT
  CTTCAGAAGAGGAGTCCAAGATTGATCTCCTTGATCGGAAGGAGGATGTGAAGAAAAAAC
  TGAAGAAGGCCTTCTGTGAGCCAGGAAATGTGGAGAACAATGGGGTTCTGTCCTTCATCA
  AGCATGTCCTTTTTCCCCTTAAGTCCGAGTTTGTGATCCTACGAGATGAGAAATGGGGTG
  GAAACAAAACCTACACAGCTTACGTGGACCTGGAAAAGGACTTTGCTGCTGAGGTTGTAC
  ATCCTGGAGACCTGAAGAATTCTGTTGAAGTCGCACTGAACAAGTTGCTGGATCCAATCC
  GGGAAAAGTTTAATACCCCTGCCCTGAAAAAACTGGCCAGCGCTGCCTACCCAGATCCCT
  CAAAGCAGAAGCCAATGGCCAAAGGCCCTGCCAAGAATTCAGAACCAGAGGAGGTCATCC
  CATCCCGGCTGGATATCCGTGTGGGGAAAATCATCACTGTGGAGAAGCACCCAGATGCAG
  ACAGCCTGTATGTAGAGAAGATTGACGTGGGGGAAGCTGAACCACGGACTGTGGTGAGCG
  GCCTGGTACAGTTCGTGCCCAAGGAGGAACTGCAGGACAGGCTGGTAGTGGTGCTGTGCA
  ACCTGAAACCCCAGAAGATGAGAGGAGTCGAGTCCCAAGGCATGCTTCTGTGTGCTTCTA
  TAGAAGGGATAAACCGCCAGGTTGAACCTCTGGACCCTCCGGCAGGCTCTGCTCCTGGTG
  AGCACGTGTTTGTGAAGGGCTATGAAAAGGGCCAACCAGATGAGGAGCTCAAGCCCAAGA
  AGAAAGTCTTCGAGAAGTTGCAGGCTGACTTCAAAATTTCTGAGGAGTGCATCGCACAGT
  GGAAGCAAACCAACTTCATGACCAAGCTGGGCTCCATTTCCTGTAAATCGCTGAAAGGGG
  GGAACATTAGCTAGCCAGCCCAGCATCTTCCCCCCTTCTTCCACCACTGAGTCATCTGCT
  GTCTCTTCAGTCTGCTCCATCCATCACCCATTTACCCATCTCTCAGGACACGGAAGCAGC
  GGGTTTGGACTCTTTATTCGGTGCAGAACTCGGCAAGGGGCAGCTTACCCTCCCCAGAAC
  CCAGGATCATCCTGTCTGGCTGCAGTGAGAGACCAACCCCTAACAAGGGCTGGGCCACAG
  CAGGGAGTCCAGCCCTACCTTCTTCCCTTGGCAGCTGGAGAAATCTGGTTTCAATATAAC
  TCATTTAAAAATTTATGCCACAGTCCTTATAATTGGAAAAATACTGGTGCCCAGGTTTTC
  TTGGAGTTATCCAAGCAGCTGCGCCCCTAGCTGGGATCTGGTACCTGGACTAGGCTAATT
  ACAGCTTCTCCCCAACAGGAAACTGTGGGATTTGAAAAGGAAAGGGAAGGGAAAACAGAG
  AACCTAGTGGTCTACCAAGTGGTTGGCAACTTTCCCAATGTCTGCTTACTCTGAGGCTTG
  GCACTGGGGGCCAGGGCCTGCCCCAGGGCTCCTGGAATTTCCCTTGATCCAGCTAGGCTG
  GGACACTCCCTAAATCAGCTGCGTGTTGTTAGCATCAGGCAGAATGAATGGCAGAGAGTG
  ATTCTGTCTTCATAGAGGGTGGGGTACTTCTCCGTAAGGCATCTCAGTCAAATCCCCATC
  ACTGTCATAAATTCAAATAAAATGTCTGAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322455 unedited
  TATCATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGGGGGCTCTGGTGCCGGGCTGAGCGGGG
  GAAGCAGGGGTAGCGGAGCCATGGGGGACGCTCCCAGCCCTGAAGAGAAACTGCACCTTA
  TCACCCGGAACCTGCAGGAGGTTCTGGGGGAAGAGAAGCTGAAGGAGATACTGAAGGAGC
  GGGAACTTAAAATTTACTGGGGAACGGCAACCACGGGCAAACCACATGTGGCTTACTTTG
  TGCCCATGTCAAAGATTGCAGACTTCTTAAAGGCAGGGTGTGAGGTAACAATTCTGTTTG
  CGGACCTCCACGCATACCTGGATAACATGAAAGCCCCATGGGAACTTCTAGAACTCCGAG
  TCAGTTACTATGAGAATGTGATCAAAGCAATGCTGGAGAGCATTGGTGTGCCCTTGGAGA
  AGCTCAAGTTCATCAAAGGCACTGATTACCAGCTCAGCAAAGAGTACACACTAGATGTGT
  ACAGACTCTCCTCCGTGGTCACACAGCACGATTCCAAGAAGGCTGGAGCTGAGGTGGTAA
  AGCAGTGGAGCACCCTTTGCTGAGTGGCCTCTTATACCCCGGGACTGCAAGCTTTGGATG
  AAGAGTATTTAAAAGTAGATGCCCAATTTGGAGGCATTGATCAGAGAAAGATTTTCACCT
  TTGCAGAGAAGTACCTCCCTGCACTTGGCTATTCAAAACGGGTCCATCTGATGAATCCTA
  TGGTTCAGATTACAGGCAGCAAAATGAGGCTCTTCGAGAGAGTCCAGAATGATTCTCTTG
  ATCGGAAGGAGATGTGAAGAAAAACTGAGAAGCTTTCTGTGAGCAGGAATGGTGCAAAAC
  ATGGGGTTCTGTCTATCAGCATGTCGTTACCTTAATCCGATTTGAATCTCACCAATGTAA
  AATGGGTGGAACACGATCA
• Restriction Sites: Please inquire
• ACCN: NM_003680
• ORF Size: 1587 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003680.2, NP_003671.1
• RefSeq Size: 3137
• RefSeq ORF: 1587
• Locus ID: 8565
• Domains: tRNA-synt_1b, tRNA_bind
• Protein Families: Druggable Genome
• Protein Pathways: Aminoacyl-tRNA biosynthesis
• Gene Summary: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008]