Tyrosyl tRNA synthetase (YARS) (NM_003680) Human Untagged Clone

CAT#: SC322455

YARS (untagged)-Human tyrosyl-tRNA synthetase (YARS)


  "NM_003680" in other vectors (7)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol YARS
Synonyms CMTDIC; TYRRS; YRS; YTS
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for SC322455 GGGGCTCTGGTGCCGGGCTGAGCGGGGGAAGCAGGGGTAGCGGAGCCATGGGGGACGCTC
CCAGCCCTGAAGAGAAACTGCACCTTATCACCCGGAACCTGCAGGAGGTTCTGGGGGAAG
AGAAGCTGAAGGAGATACTGAAGGAGCGGGAACTTAAAATTTACTGGGGAACGGCAACCA
CGGGCAAACCACATGTGGCTTACTTTGTGCCCATGTCAAAGATTGCAGACTTCTTAAAGG
CAGGGTGTGAGGTAACAATTCTGTTTGCGGACCTCCACGCATACCTGGATAACATGAAAG
CCCCATGGGAACTTCTAGAACTCCGAGTCAGTTACTATGAGAATGTGATCAAAGCAATGC
TGGAGAGCATTGGTGTGCCCTTGGAGAAGCTCAAGTTCATCAAAGGCACTGATTACCAGC
TCAGCAAAGAGTACACACTAGATGTGTACAGACTCTCCTCCGTGGTCACACAGCACGATT
CCAAGAAGGCTGGAGCTGAGGTGGTAAAGCAGGTGGAGCACCCTTTGCTGAGTGGCCTCT
TATACCCCGGACTGCAGGCTTTGGATGAAGAGTATTTAAAAGTAGATGCCCAATTTGGAG
GCATTGATCAGAGAAAGATTTTCACCTTTGCAGAGAAGTACCTCCCTGCACTTGGCTATT
CAAAACGGGTCCATCTGATGAATCCTATGGTTCCAGGATTAACAGGCAGCAAAATGAGCT
CTTCAGAAGAGGAGTCCAAGATTGATCTCCTTGATCGGAAGGAGGATGTGAAGAAAAAAC
TGAAGAAGGCCTTCTGTGAGCCAGGAAATGTGGAGAACAATGGGGTTCTGTCCTTCATCA
AGCATGTCCTTTTTCCCCTTAAGTCCGAGTTTGTGATCCTACGAGATGAGAAATGGGGTG
GAAACAAAACCTACACAGCTTACGTGGACCTGGAAAAGGACTTTGCTGCTGAGGTTGTAC
ATCCTGGAGACCTGAAGAATTCTGTTGAAGTCGCACTGAACAAGTTGCTGGATCCAATCC
GGGAAAAGTTTAATACCCCTGCCCTGAAAAAACTGGCCAGCGCTGCCTACCCAGATCCCT
CAAAGCAGAAGCCAATGGCCAAAGGCCCTGCCAAGAATTCAGAACCAGAGGAGGTCATCC
CATCCCGGCTGGATATCCGTGTGGGGAAAATCATCACTGTGGAGAAGCACCCAGATGCAG
ACAGCCTGTATGTAGAGAAGATTGACGTGGGGGAAGCTGAACCACGGACTGTGGTGAGCG
GCCTGGTACAGTTCGTGCCCAAGGAGGAACTGCAGGACAGGCTGGTAGTGGTGCTGTGCA
ACCTGAAACCCCAGAAGATGAGAGGAGTCGAGTCCCAAGGCATGCTTCTGTGTGCTTCTA
TAGAAGGGATAAACCGCCAGGTTGAACCTCTGGACCCTCCGGCAGGCTCTGCTCCTGGTG
AGCACGTGTTTGTGAAGGGCTATGAAAAGGGCCAACCAGATGAGGAGCTCAAGCCCAAGA
AGAAAGTCTTCGAGAAGTTGCAGGCTGACTTCAAAATTTCTGAGGAGTGCATCGCACAGT
GGAAGCAAACCAACTTCATGACCAAGCTGGGCTCCATTTCCTGTAAATCGCTGAAAGGGG
GGAACATTAGCTAGCCAGCCCAGCATCTTCCCCCCTTCTTCCACCACTGAGTCATCTGCT
GTCTCTTCAGTCTGCTCCATCCATCACCCATTTACCCATCTCTCAGGACACGGAAGCAGC
GGGTTTGGACTCTTTATTCGGTGCAGAACTCGGCAAGGGGCAGCTTACCCTCCCCAGAAC
CCAGGATCATCCTGTCTGGCTGCAGTGAGAGACCAACCCCTAACAAGGGCTGGGCCACAG
CAGGGAGTCCAGCCCTACCTTCTTCCCTTGGCAGCTGGAGAAATCTGGTTTCAATATAAC
TCATTTAAAAATTTATGCCACAGTCCTTATAATTGGAAAAATACTGGTGCCCAGGTTTTC
TTGGAGTTATCCAAGCAGCTGCGCCCCTAGCTGGGATCTGGTACCTGGACTAGGCTAATT
ACAGCTTCTCCCCAACAGGAAACTGTGGGATTTGAAAAGGAAAGGGAAGGGAAAACAGAG
AACCTAGTGGTCTACCAAGTGGTTGGCAACTTTCCCAATGTCTGCTTACTCTGAGGCTTG
GCACTGGGGGCCAGGGCCTGCCCCAGGGCTCCTGGAATTTCCCTTGATCCAGCTAGGCTG
GGACACTCCCTAAATCAGCTGCGTGTTGTTAGCATCAGGCAGAATGAATGGCAGAGAGTG
ATTCTGTCTTCATAGAGGGTGGGGTACTTCTCCGTAAGGCATCTCAGTCAAATCCCCATC
ACTGTCATAAATTCAAATAAAATGTCTGAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAA
>OriGene 5' read for SC322455 unedited
TATCATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
GAATTCCCGGGATATCGTCGACCCACGCGTCCGGGGGCTCTGGTGCCGGGCTGAGCGGGG
GAAGCAGGGGTAGCGGAGCCATGGGGGACGCTCCCAGCCCTGAAGAGAAACTGCACCTTA
TCACCCGGAACCTGCAGGAGGTTCTGGGGGAAGAGAAGCTGAAGGAGATACTGAAGGAGC
GGGAACTTAAAATTTACTGGGGAACGGCAACCACGGGCAAACCACATGTGGCTTACTTTG
TGCCCATGTCAAAGATTGCAGACTTCTTAAAGGCAGGGTGTGAGGTAACAATTCTGTTTG
CGGACCTCCACGCATACCTGGATAACATGAAAGCCCCATGGGAACTTCTAGAACTCCGAG
TCAGTTACTATGAGAATGTGATCAAAGCAATGCTGGAGAGCATTGGTGTGCCCTTGGAGA
AGCTCAAGTTCATCAAAGGCACTGATTACCAGCTCAGCAAAGAGTACACACTAGATGTGT
ACAGACTCTCCTCCGTGGTCACACAGCACGATTCCAAGAAGGCTGGAGCTGAGGTGGTAA
AGCAGTGGAGCACCCTTTGCTGAGTGGCCTCTTATACCCCGGGACTGCAAGCTTTGGATG
AAGAGTATTTAAAAGTAGATGCCCAATTTGGAGGCATTGATCAGAGAAAGATTTTCACCT
TTGCAGAGAAGTACCTCCCTGCACTTGGCTATTCAAAACGGGTCCATCTGATGAATCCTA
TGGTTCAGATTACAGGCAGCAAAATGAGGCTCTTCGAGAGAGTCCAGAATGATTCTCTTG
ATCGGAAGGAGATGTGAAGAAAAACTGAGAAGCTTTCTGTGAGCAGGAATGGTGCAAAAC
ATGGGGTTCTGTCTATCAGCATGTCGTTACCTTAATCCGATTTGAATCTCACCAATGTAA
AATGGGTGGAACACGATCA
Restriction Sites Please inquire     
ACCN NM_003680
ORF Size 1587 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_003680.2, NP_003671.1
RefSeq Size 3137
RefSeq ORF 1587
Locus ID 8565
Domains tRNA-synt_1b, tRNA_bind
Protein Families Druggable Genome
Protein Pathways Aminoacyl-tRNA biosynthesis
Gene Summary Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008]

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