CABLES1 (NM_138375) Human Untagged Clone

CAT#: SC322553

CABLES1 (untagged)-Human Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CABLES1
• Synonyms: CABL1; CABLES; HsT2563; IK3-1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322553 GGCCATTTTTCTTCCTGGTGTTTGAATGACTCATAAAATGAGTTTGGAGTGGTCTGAAGC
  CTCTGCCTCCTTCCTTGAATGCTTTCTAAGAGGGGCTGCCATGCAAGAATATATGCTGAT
  TTTCCCATACGGCGCCTCATCTCCCAGAGATCTTCCTTGGAGACCCTGGAAGATATTGAG
  GAGAACGCCCCTCTCCGGAGATGTCGAACTCTCTCAGGTTCACCCAGACCAAAGAATTTT
  AAGAAGATTCATTTTATCAAGAACATGCGGCAACACGATACCAGGAATGGCAGAATAGTC
  CTTATCAGTGGCAGAAGATCCTTCTGTAGTATATTTTCAGTGCTGCCGTATCGCGACAGT
  ACCCAAGTCGGGGACTTGAAGTTGGACGGAGGAAGACAATCAACTGGTGCAGTGAGTTTG
  AAAGAGATCATTGGTCTGGAAGGTGTGGAGCTGGGTGCTGATGGGAAGACTGTTTCCTAT
  ACCCAATTTCTGTTACCCACAAATGCCTTTGGAGCCCGGAGAAATACCATAGACTCCACC
  TCCTCTTTCTCCCAGTTCCGTAACCTGAGCCACCGCAGCCTCTCCATAGGCCGGGCAAGC
  GGCACCCAGGGGAGCCTCGACACAGGTAGTGACCTGGGAGACTTTATGGACTATGACCCA
  AATCTCTTGGATGACCCCCAGTGGCCTTGTGGCAAACACAAACGCGTTCTGATCTTCCCT
  TCCTACATGACAACAGTGATTGACTACGTGAAGCCCTCGGATCTCAAGAAGGACATGAAC
  GAGACCTTCAAGGAGAAGTTTCCTCACATTAAGCTGACACTCAGCAAAATTAGGAGTCTG
  AAACGAGAGATGCGGAAGCTTGCGCAGGAGGACTGTGGCCTTGAGGAGCCCACGGTGGCC
  ATGGCCTTCGTCTACTTTGAAAAGCTCGCCCTCAAGGGGAAACTCAACAAACAGAACCGG
  AAGCTGTGTGCTGGGGCATGTGTGCTGTTAGCAGCCAAAATTGGAAGTGACCTCAAAAAA
  CACGAAGTCAAGCATTTAATTGACAAACTGGAAGAGAAGTTCCGGCTGAACAGGCGAGAA
  CTGATTGCCTTTGAATTCCCGGTGTTAGTGGCCTTGGAATTCGCCCTCCACTTGCCCGAG
  CACGAAGTCATGCCCCACTACAGACGGCTGGTCCAGAGTTCCTAGCACTGGCCCCGAGGA
  CAGCCAAGGGCCATTTCTTCTCAGCTTGGTGGAGCAGCACTTACTTACTACTGGAAATGA
  AAAAAAGTAGAACTCAGAATACCAGACTTTTCTTCCTCTCGACATAGTTTGGGGAGAAGC
  AGTACTAGAAACTTTCCAAGGAGTCTTGGGTGTGTAGCCAAGAGGAGCCATGAGCTATGG
  ACTCCTCAAGCACGGGAAGAGGAGGTGTGTGCTGAGAACAGAGAGGCCCTGCCCTCTGTC
  CACTAGCGAGAATCCCTAGCTGCCCCAGCCCAGTCTTTCTCCCCGGCATTCACAAACTTT
  GCAAGCGTGGTCCAGGGCCTTCTCCAGATCTGTTCCAACTTGGAGTGTGAAGGGCTTGAG
  CATACGGGGGAAGAGAGTCTGCAGAAGTTGGGGGAAAACTTTTAAAAGATACCCTCATTG
  TGTCAAAGAGTGTGCCAATCTATTTTTGTATCAGCATTGGAAGTGCACTTTCCCCTGGGG
  CGTGTGGGTGTGTGAATGTGCAAGTGTCTGAGAGATACTGCATCAGCCCTAGACCCCCAG
  AGCCAGTCCCGCCCTTTACAGAGCAGCCCTTAGCCTGGGGCCATGGGTCAGGCTGACCTT
  CAACAATTATTTCTAGATGATTTCTGGATAAGAATTGCTCTCTCGGTACCAGACAGTTTG
  ACATCCTCCACCCTTAGAAAATGACTGACATTGTTTTGTTACTGCTCCTACCCACCAAGG
  GGATAAAGAAGGCGAGTTCTGAGTGTTGGATGAGTCAGTCGCGTGGAAGGACGTGGAGCG
  TGGCGCTCTGTAACTTCCTGCCGTCTGCCACCCCGCCACGTGTATTTAACCCTCGCACTT
  TCTCCACTGTGGAGATGGCTGGGGCGGCGCCCCACAGTGTGTATTCCTGTCCTCTATGTT
  AGAGTGCATCAGAAGCACATTTACTGTGCTATTTATATCGCTATATAAAAGTGTTTTATA
  AAAACCCAGAATAGGAGCCCGACGCATGATTGGTGTTTGAGGCGTTTGCCAGCTGGGACA
  AACTGCGTTTGGAGCTGTGGTTAAGCTGACTAAGGAGGCGGTGGCTCTTTCTTAACATTC
  CCACGTGCCCAGGGCTGTTCATGCAAGATTTTAATGGTGACTTGTCCTGGCTTACTGGGA
  CAGTCTGTATGAGGCATGTCACCACACTGTCGCCTCATAGCTGCAAGAGAGAGGCACCAG
  CTGAAGTTCCCCTGACTGAAGAGAGCCTGTGGCCATGTAAAAAGAGAATTAAACTCTTGT
  TGCTTTTTGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322553 unedited
  GATATTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATGGCCATTTTTCTTCCTGGTGTTTGAATGACTCATAAAATGAGTTTG
  GAGTGGTCTGAAGCCTCTGCCTCCTTCCTTGAATGCTTTCTAAGAGGGGCTGCCATGCAA
  GAATATATGCTGATTTTCCCATACGGCGCCTCATCTCCCAGAGATCTTCCTTGGAGACCC
  TGGAAGATATTGAGGAGAACGCCCCTCTCCGGAGATGTCGAACTCTCTCAGGTTCACCCA
  GACCAAAGAATTTTAAGAAGATTCATTTTATCAAGAACATGCGGCAACACGATACCAGGA
  ATGGCAGAATAGTCCTTATCAGTGGCAGAAGATCCTTCTGTAGTATATTTTCAGTGCTGC
  CGTATCGCGACAGTACCCAAGTCGGGGACTTGAAGTTGGACGGAGGAAGACAATCAACTG
  GTGCAGTGAGTTTGAAAGAGATCATTGGTCTGGAAGGTGTGGAGCTGGGTGCTGATGGGA
  AGACTGTTTCCTATACCCAATTTCTGTTACCCACAAATGCCTTTGGAGCCCGGAGAAATA
  CCATAGACTCCACCTCCTCTTTTCTCCCAGTTCCGTAACCTGAGCCACCGCAGCCTCTCC
  ATAGCCCGGGCAAGCGGCACCCAGGGGAGCCTCGACACAGGTAGTGACCTGGGAGACTTT
  ATGGACTATGACCCAAATCTCTTGGATGACCCCCAGTGGCCCTTGTGGCAAACACAAACG
  CGTTCTGATCTTCCCTTCCTACATGACACAGTGATTGACTACGTGAAGCCCTCGATCTCA
  GACGACATGACGAGACCTTCAGGAGAGTTTCCTCACATTAGCTGACCCTCAGCAAATTAA
  GAGTCTGAAACGAAGATGCGAGCTGGCCCAGAGACTGTGTCTGAGACCCACGTGCCATGC
  CTTCGCTCACTTGAAGCTGACT
• Restriction Sites: Please inquire
• ACCN: NM_138375
• ORF Size: 1107 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_138375.1, NP_612384.1
• RefSeq Size: 2523
• RefSeq ORF: 1107
• Locus ID: 91768
• Gene Summary: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  Transcript Variant: This variant (1) uses an alternate first exon that contains the translation initiation site, resulting in an isoform (1) with a distinct N-terminus.