Apg10 (ATG10) (NM_031482) Human Untagged Clone

CAT#: SC322562

ATG10 (untagged)-Human ATG10 autophagy related 10 homolog (S. cerevisiae) (ATG10), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ATG10
• Synonyms: APG10; APG10L; pp12616
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322562 ACCTGACTGAAGGAGGCCGCGGACCTGACTGAAGGAGGCCACGGCCACTTCTGGTTGGCC
  TCGGGGCGCGCTGGCTCGGCTCTTCCTCCGCCCTCGAGGCCCCCGCAGTCCCATCATTCA
  GTTCCGTAGGGTCACCGGCGCGGCAGTGGCCTCGCAGGGCGCTGGGTCCCTCTCCCCAGC
  TCTCCTCCCCCTGGCCGCGTCGCCCCGCCCTCGCCGGGCTGGGCTGCGGGGTCAGGGGCC
  GAGCGGAGAGGGTTATCATTTAACATGGAAGAAGATGAGTTCATTGGAGAAAAAACATTC
  CAACGTTATTGTGCAGAATTCATTAAACATTCACAACAGATAGGTGATAGTTGGGAATGG
  AGACCATCAAAGGACTGTTCTGATGGCTACATGTGCAAAATACACTTTCAAATTAAGAAT
  GGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCCATGGAG
  GAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAA
  GTGATTAAATATGAGTATCATGTCTTATATTCCTGTAGCTACCAAGTGCCTGTACTTTAC
  TTTAGGGCAAGCTTTTTAGATGGGAGACCTTTAACTCTGAAGGACATATGGGAAGGAGTT
  CATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAA
  CATCCAATACTTGGGCAACCCTTTTTTGTACTTCATCCCTGCAAGACGAATGAATTCATG
  ACTCCTGTATTAAAGAATTCTCAGAAAATCAATAAGAATGTCAACTATATCACATCATGG
  CTGAGCATTGTAGGGCCAGTTGTTGGGCTGAATCTACCTCTGAGTTATGCCAAAGCAACG
  TCTCAGGATGAACGAAATGTCCCTTAACAAGATTCTTCTATTGAGTTTAGGAATTGCGGC
  ACGAAGAATGCCAAGAGTTTACCTGGCCAGCCCTGGCTTTAATAGGACTGATACCATGGA
  ATATTTCATCTCACCAAGATGTGACATGGATTATTTTTCCCTTGGACACAAATGTCTACA
  GCAACTGGTGTTTGATAGGCTGAATGTTTAGAAGAAACACTTCAAAGGGATACATCATGG
  CCAGGCATGGTGGCTCACACCTGTAATCCAAGCACTTTGGGAGGCCAAGGTGGGAGCATC
  ACTTGATCCTGGGAGTTCGAGACCAGCCTGGGCAACATGGTGAAACCCTGTCGGTACAAA
  AAAATACAAAAATTTGCCTGTTTATGGTGGTGTGTTCCTGTAGTCCCAGCTCCCCAGGAG
  GCTGAGGTGGGAGGTTGGCTTTAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGACTGTG
  CCACTGCAGTCCAGCCTGGGTGACAGAGCCAGACACTGTCTCGGGAAAAAAAAAAAAAAA
  GACACATCACTATAAATAGCAAAAAAACAAATCTAACTTATTAATACTAGGAATACCAAC
  ATTATTAGGGCACTTGCAGGTTATTCTTTTCTAGGCCAAGTACTTCACTTCCATTTGTCT
  GACATGGAGATTGAGGGAGAAATGTATTTGTGTGTTCATTTTAATGTAAGATATATAAAA
  ATTAAATTACTGGATTTACCTGTCCCTGAAACTGGTGTTATAAACATGACCTATCTTAAG
  TGATTTTCCCACAATCAAACTCAGGAACAATAGATTATTTCTGTTTTACTCCAAAAGAGA
  GAGAGAGAGTGAGTGTGAGTGTGTGTGTGTGTGTGTGTGTATGTGTGGGTGTTTGTGTAG
  ATAGTTGTAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322562 unedited
  GTATATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGACCTGACTGAAGGAGGCCGCGGACCTG
  ACTGAAGGAGGCCACGGCCACTTCTGGTTGGCCTCGGGGCGCGCTGGCTCGGCTCTTCCT
  CCGCCCTCGAGGCCCCCGCAGTCCCATCATTCAGTTCCGTAGGGTCACCGGCGCGGCAGT
  GGCCTCGCAGGGCGCTGGGTCCCTCTCCCCAGCTCTCCTCCCCCTGGCCGCGTCGCCCCG
  CCCTCGCCGGGCTGGGCTGCGGGGTCAGGGGCCGAGCGGAGAGGGTTATCATTTAACATG
  GAAGAAGATGAGTTCATTGGAGAAAAAACATTCCAACGTTATTGTGCAGAATTCATTAAA
  CATTCACAACAGATAGGTGATAGTTGGGAATGGAGACCATCAAAGGACTGTTCTGATGGC
  TACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCA
  TCTACCCATGGACAGACATGTCTTCCCATGGAGGAGGCTTTCGAGCTACCCTTGGATGAT
  TGTGAAGTGATTGAAACTGCAGCAGCGTCCGAAGTGATTAAATATGAGTATCATGTCTTA
  TATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGA
  CCTTTAACTCTGAAGGACATATGGGAAGGAGTTCATGAGTGCTATAAGATGCGACTGCTA
  CAGGGACCATGGGACACTATTACGCAACAGGAACATCCAATACTTGGGCAACCCTTTTTT
  GTACTTCATCCCTGCAGACGATGATTCATGACTCCTGTATTAAAGATCTCAGAAAATCAA
  TAAGATGTCACTATTATACACATCATGCTGACCATTGTAGGCCAGTGTGGACCTGATCTA
  CCCTCTGAGTTATGGCCTAGACCCACCGTCTCTCAGGGAGTG
• Restriction Sites: Please inquire
• ACCN: NM_031482
• ORF Size: 663 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031482.3, NP_113670.1
• RefSeq Size: 1818
• RefSeq ORF: 663
• Locus ID: 83734
• Gene Summary: Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (2) lacks an exon in the 5' UTR, as compared to variant 1.