CROT (NM_021151) Human Untagged Clone

CAT#: SC322598

CROT (untagged)-Human carnitine O-octanoyltransferase (CROT), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CROT
• Synonyms: COT
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322598 GGGAGCGAGCCGGTGCTGCTGCAGGCTGAGGCTGCGGCAGAGGCGGCGAGGCGCGGGCGG
  TGAGGACGGACAGTCACCGACTTAGTCCAGTTCCCTGTGATCTCAAAACAATTGTTGCAG
  CAGGCTCCTGGCAGTCTCAAGCAGTTCATCTTCTTGGTGTACTGGTTTCCTATTGTGATT
  TTATCATGGAAAATCAATTGGCTAAATCAACTGAAGAACGAACATTTCAGTACCAGGATT
  CTCTTCCATCACTGCCTGTTCCTTCACTTGAAGAATCATTAAAAAAATACCTTGAATCAG
  TGAAACCATTTGCAAATCAAGAAGAATATAAGAAAACTGAAGAAATAGTTCAAAAATTTC
  AAAGTGGGATTGGAGAAAAATTGCACCAGAAATTGCTTGAAAGAGCAAAAGGAAAAAGAA
  ATTGGCTGGAAGAGTGGTGGCTGAATGTTGCCTATCTGGATGTTCGTATACCATCACAAT
  TGAATGTCAACTTTGCGGGTCCTGCAGCTCATTTTGAACACTACTGGCCTCCAAAGGAAG
  GGACTCAATTAGAAAGAGGAAGTATAACTCTTTGGCATAACTTGAACTACTGGCAGCTAT
  TAAGAAAAGAAAAAGTGCCTGTTCATAAAGTTGGAAATACTCCTCTAGATATGAATCAAT
  TCCGAATGCTATTTTCTACCTGCAAGGTTCCAGGAATTACTAGAGACTCCATTATGAATT
  ATTTTAGGACTGAGAGTGAAGGGCGTTCCCCAAACCACATTGTAGTGCTGTGTCGAGGCC
  GAGCTTTTGTCTTTGATGTAATACATGAAGGATGTTTGGTCACCCCGCCAGAGCTTCTCA
  GACAACTGACATATATCCACAAGAAGTGCCATAGTGAACCTGATGGACCTGGGATTGCAG
  CATTAACTAGTGAGGAGCGAACTCGATGGGCTAAGGCACGAGAATATCTGATTGGTCTTG
  ATCCAGAGAACTTGGCTTTGTTAGAAAAAATTCAGAGTAGTTTACTGGTATATTCCATGG
  AGGATAGCAGTCCACATGTAACACCAGAGGATTATTCTGAGATTATTGCAGCCATCCTTA
  TTGGAGATCCAACAGTACGCTGGGGTGACAAATCCTATAACTTGATTTCCTTTTCTAATG
  GAGTATTTGGCTGTAATTGTGATCATGCTCCTTTTGATGCAATGATTATGGTGAACATCA
  GTTATTATGTGGATGAGAAAATTTTTCAGAATGAAGGAAGATGGAAGGGTTCAGAGAAGG
  TACGAGATATACCACTTCCAGAAGAGCTCATTTTCATTGTGGATGAGAAAGTTTTAAATG
  ACATCAACCAAGCTAAAGCCCAGTATCTCAGGGAGGCATCTGATCTACAGATTGCGGCTT
  ATGCCTTTACATCTTTTGGCAAAAAGCTAACCAAGAACAAGATGCTTCACCCGGATACGT
  TTATTCAGCTTGCACTTCAGCTGGCCTATTACAGACTTCATGGACACCCTGGTTGTTGCT
  ATGAAACAGCTATGACAAGACATTTTTATCATGGCCGTACAGAGACTATGCGATCATGCA
  CAGTTGAAGCAGTGAGGTGGTGCCAGTCCATGCAGGATCCTTCTGTCAATCTTCGTGAGC
  GGCAGCAAAAGATGTTACAAGCTTTTGCAAAGCATAATAAAATGATGAAAGATTGTTCAG
  CTGGAAAAGGATTTGATCGTCACCTTTTAGGTCTCTTACTCATAGCAAAAGAGGAAGGTC
  TTCCTGTTCCAGAACTCTTTACGGACCCACTTTTTTCCAAAAGCGGAGGAGGTGGAAATT
  TTGTTCTCTCAACAAGTCTGGTTGGCTATTTACGAGTCCAGGGAGTGGTAGTTCCCATGG
  TACACAATGGTTATGGATTTTTCTACCATATCAGAGATGACAGGTTTGTTGTGGCCTGTT
  CAGCCTGGAAATCCTGTCCCGAGACTGATGCGGAAAAGCTAGTTCAGCTGACTTTTTGTG
  CTTTTCATGATATGATACAGCTGATGAACTCTACTCATCTTTAGAGATGAATCATCTATT
  AAGCACTTACCAAAACATATCATTAAACTGAGTGCTGGGAGTGAGTTGGTAATATGAGAT
  GGGAAGGAATGTTGACTTGCTAACATTCCTTTAACAAGTTAAGAAAACTTGTTAAATGTA
  GAAATTAGTAGAATCATGCTCTCTAAATTTATTCTGCCATAGAAGGTAGAAATATTTTTA
  AGCTCCTCTGATGCAGCAGCAATGCAAATTATGACATAGTGAATATAGAACTATGCAGTA
  TTTAAGCCTCAACAATCCAAATCTACAAACTTTAACAATGCAAGTCTTACTCTAATTTTT
  AAGTATTTTTGTTGGTACTTACATGGGTTATAAATCCTCTCTCTGGACATCAATGTAGAG
  TCCATCTTTCAAGCACTTTAATTTTTTTAGCTGCCAAAGGGTATGAATTACATTATTGTA
  TGCTAATTTCCCTGAAATCAATGCCTTCTATGTTCACCACAGGGATACAAGCCTGTTATG
  TTTGATGGGAAAGACCACTACAATCTAATGGTGATCTAAAATAACTTTTTTGGGCTGGGT
  GCAGTGGCTCATGCCTATAATCTTAGCACTTTGGGAGGCCAAGGTAGGAGGATTGCTTGA
  AGCTAGGAGTTTGAGACCAGCCTGGGCAACAGGGTAAGGTCCTGTCTCTACAAGATCAAA
  AACTTAGCCGGGTATGGTGGTGCATGTGTGCCTGTAGTCCAAGCTACTTGAAGGCTGAGA
  CAGGAGGATCGGTTGAGCCCAGGAGGTTGTGGCTGCAGTGAGCTGTGATGTGCCCTTATG
  CTATAGCCTGGGCAAGAGCGTGAGACCCTGTCTCAAAGAAGAAAAAAAGAGAAAAATAAC
  TCTTTTGAACAAACAGACAAATTAGCTAGTAGTATGGAGATGTATACCCTCTATTACACA
  CATAAAACCGTAACAAAATTCATTGTGGTGTATTATAATTAGTTTTGTGAATAGAAAAAT
  AAAGCACTTATGTTTAAATTTGTTACAGTGACTTTTAAAGGATTAATGTTGAATCACATT
  GTCAGAATTTTTTCCTCCTCGCTGTTCAATTTTGTAGTTTTTACTCTCAAAAAATGAAAT
  TCTCAAAATTATATAGCTTTTTGTTTTGTTTGAATAAATGATTCATTCCTGTTAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322598 unedited
  GAGCATTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATGGGAGCGAGCCGGTGCTGCTGCCGGCCGAGGCTGCTGGCTGGCTAC
  CAGGTGCGGGTGGTGAGGACGGACCTGCCCGGCCTTTCACCCTGCCCTGTGATCCGCTGC
  CGCCGCGGGGCCGGGCCCTGGCCTCGCCATCCTTCATGAAGCATGGCTACTGGTTTCCAA
  CTGTGATTTCTGATGTGTTGGACCTGGCGTTACCCACTGAACAACAAACCTTACAGAACA
  GTGCTTCTATTTTGTGGATGTTTTTTCCTTCATTTGAAGAATCATTGGTGGAATACCTTG
  ACTTGTTGATCCCATTTGCAAATAAGCAAAAATATAAGAAAACTGGCCATATAGTGCTCA
  AATTTTGCTGTGGGATTGGAGAAAAATTGCACAAGCTCATTGCTTGCAACAGCAAAAGGA
  AAATAGAAATTGGCTGGATGAGTGGTGGCTGGATGTTGCTTATCTGTAAGTCTTTGTGCC
  ATCTAGAATGAGTGTAAACTGAGTGGATCGTGCAGCTCATTTTTCACACATACTGCTGTA
  CATAGGACTGGTCTCATATTAAAAACAAGAAAGTATAAACTCTTTGGCATACCAATGAAA
  CTACTCTGCAGCTATTCCAGAAGACTAGAAACATGCGATGCTTCGTAAACATTGAGAAGG
  ACGTGTAAAGAATAGCGAATCCCACTGCAGACAGCTACTATAATACCTGGCAGAGTCCCA
  GGGTAAATCACTAGAGACCTCCCCTGACTGAATTGATGTCACTGACTGAGTACTGTACGG
  GACGTTCTTATGACTTCAACTTTGGAACTAGCTGAGGTCCGTAGGAACCGTACATTTCTG
  TCCTTTTGATGTTAATTACACATGAACGCATTGTAGGTAGACACCGAGATCAGAAGTCTT
  TTGCCTTGTCAAACTGACATAATACGCAGACCTGACATATTGTGAATCCTGTATGTGGAT
  CCTTTG
• Restriction Sites: Please inquire
• ACCN: NM_021151
• ORF Size: 1839 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_021151.2, NP_066974.2
• RefSeq Size: 3211
• RefSeq ORF: 1839
• Locus ID: 54677
• Domains: Carn_acyltransf
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The resulting isoform (2) is shorter but has the identical N- and C-termini compared to isoform 1.