NKG2D (KLRK1) (NM_007360) Human Untagged Clone
CAT#: SC322611
KLRK1 (untagged)-Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1)
"NM_007360" in other vectors (7)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | KLRK1 |
Synonyms | CD314; D12S2489E; KLR; NKG2-D; NKG2D |
Vector | pCMV6-AC |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>OriGene sequence for SC322611
TGAGGACATATCTAAATTTTCTAGTTTTATAGAAGGCTTTTATCCACAAGAATCAAGATC
TTCCCTCTCTGAGCAGGAATCCTTTGTGCATTGAAGACTTTAGATTCCTCTCTGCGGTAG ACGTGCACTTATAAGTATTTGATGGGGTGGATTCGTGGTCGGAGGTCTCGACACAGCTGG GAGATGAGTGAATTTCATAATTATAACTTGGATCTGAAGAAGAGTGATTTTTCAACACGA TGGCAAAAGCAAAGATGTCCAGTAGTCAAAAGCAAATGTAGAGAAAATGCATCTCCATTT TTTTTCTGCTGCTTCATCGCTGTAGCCATGGGAATCCGTTTCATTATTATGGTAGCAATA TGGAGTGCTGTATTCCTAAACTCATTATTCAACCAAGAAGTTCAAATTCCCTTGACCGAA AGTTACTGTGGCCCATGTCCTAAAAACTGGATATGTTACAAAAATAACTGCTACCAATTT TTTGATGAGAGTAAAAACTGGTATGAGAGCCAGGCTTCTTGTATGTCTCAAAATGCCAGC CTTCTGAAAGTATACAGCAAAGAGGACCAGGATTTACTTAAACTGGTGAAGTCATATCAT TGGATGGGACTAGTACACATTCCAACAAATGGATCTTGGCAGTGGGAAGATGGCTCCATT CTCTCACCCAACCTACTAACAATAATTGAAATGCAGAAGGGAGACTGTGCACTCTATGCC TCGAGCTTTAAAGGCTATATAGAAAACTGTTCAACTCCAAATACATACATCTGCATGCAA AGGACTGTGTAAAGATGATCAACCATCTCAATAAAAGCCAGGAACAGAGAAGAGATTACA CCAGCGGTAACACTGCCAACCGAGACTAAAGGAAACAAACAAAAACAGGACAAAATGACC AAAGACTGTCAGATTTCTTAGACTCCACAGGACCAAACCATAGAACAATTTCACTGCAAA CATGCATGATTCTCCAAGACAAAAGAAGAGAGATCCTAAAGGCAATTCAGATATCCCCAA GGCTGCCTCTCCCACCACAAGCCCAGAGTGGATGGGCTGGGGGAGGGGTGCTGTTTTAAT TTCTAAAGGTAGGACCAACACCCAGGGGATCAGTGAAGGAAGAGAAGGCCAGCAGATCAG TGAGAGTGCAACCCCACCCTCCACAGGAAATTGCCTCATGGGCAGGGCCACAGCAGAGAG ACACAGCATGGGCAGTGCCTTCCCTGCCTGTGGGGGTCATGCTGCCACTTTTAATGGGTC CTCCACCCAACGGGGTCAGGGAGGTGGTGCTGCCCTAGTGGGCCATGATTATCTTAAAGG CATTATTCTCCAGCCTTAAGATCTTAGGACGTTTCCTTTGCTATGATTTGTACTTGCTTG AGTCCCATGACTGTTTCTCTTCCTCTCTTTCTTCCTTTTGGAATAGTAATATCCATCCTA TGTTTGTCCCACTATTGTATTTTGGAAGCACATAACTTGTTTGGTTTCACAGGTTCACAG TTAAGAAGGAATTTTGCCTCTGAATAAATAGAATCTTGAGTCTCATGCAAAAAAAAAAAA AAAAAAAAAAAAAAA >OriGene 5' read for SC322611 unedited
TTAGTATCTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGT CCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGCTGAGGACATATCTAAATTTTCTA GTTTTATAGAAGGCTTTTATCCACAAGAATCAAGATCTTCCCTCTCTGAGCAGGAATCCT TTGTGCATTGAAGACTTTAGATTCCTCTCTGCGGTAGACGTGCACTTATAAGTATTTGAT GGGGTGGATTCGTGGTCGGAGGTCTCGACACAGCTGGGAGATGAGTGAATTTCATAATTA TAACTTGGATCTGAAGAAGAGTGATTTTTCAACACGATGGCAAAAGCAAAGATGTCCAGT AGTCAAAAGCAAATGTAGAGAAAATGCATCTCCATTTTTTTTCTGCTGCTTCATCGCTGT AGCCATGGGAATCCGTTTCATTATTATGGTAGCAATATGGAGTGCTGTATTCCTAAACTC ATTATTCAACCAAGAAGTTCAAATTCCCTTGACCGAAAGTTACTGTGGCCCATGTCCTAA AAACTGGATATGTTACAAAAATAACTGCTACCAATTTTTTTGATGAGAGTAAAAACTGGT ATGAGAGCCAGGCTTCTTGTATGTCTCAAAATGCCAGCCCTTCTGAAAGTATACAGCAAA GAGGACCAGGATTTACTTAAACTGGTGAAGTCATATCATTGGATGGGACTAGTACACATT CCCAACAAATGGATTCTTGGCAGTGGAAGGATGGCTCCATTCTTCTCACCCCAACCCTAC TAACAATATTGAAATGCAAAGGGAGACTGTGCACTCTATGCCTCGAGCTTTCAAGGCTAT TATAGAAACTGTTCACTCCAAATACATACATCTGCATGCAAAGGACTGTTGTAAGATGAT CACATTCTCATAAAGCCCAGAACGAGAAGAGATTACCAACGGTACCCTGCCACGGATCCT AAGGCAACAATCATAGCCAGGACCAAAT |
Restriction Sites | Please inquire |
ACCN | NM_007360 |
ORF Size | 651 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Reference Data | |
RefSeq | NM_007360.1, NP_031386.1 |
RefSeq Size | 1770 |
RefSeq ORF | 651 |
Locus ID | 22914 |
Domains | CLECT |
Protein Families | Transmembrane |
Protein Pathways | Natural killer cell mediated cytotoxicity |
Gene Summary | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster. [provided by RefSeq, Dec 2010] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC115560 | KLRK1 (untagged)-Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1) |
USD 310.00 |
|
RC208050 | KLRK1 (Myc-DDK-tagged)-Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1) |
USD 98.00 |
|
RG208050 | KLRK1 (GFP-tagged) - Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1) |
USD 460.00 |
|
RC208050L1 | Lenti ORF clone of Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1), Myc-DDK-tagged |
USD 768.00 |
|
RC208050L2 | Lenti ORF clone of Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1), mGFP tagged |
USD 620.00 |
|
RC208050L3 | Lenti ORF clone of Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1), Myc-DDK-tagged |
USD 620.00 |
|
RC208050L4 | Lenti ORF clone of Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1), mGFP tagged |
USD 620.00 |
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