CD75 (ST6GAL1) (NM_003032) Human Untagged Clone

CAT#: SC322722

ST6GAL1 (untagged)-Human ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 (ST6GAL1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ST6GAL1
• Synonyms: SIAT1; ST6GalI; ST6N
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322722 GAGGAGGTTCCTGTAGGGCGGCACAACCAGGGAGGGCGTGGAAGCTCTGCATCCCTTCTC
  CCATACCTTGCTCTACACATCTCTTCATCTGTATCCTCTGCAGCATCCTTGATGATAAAC
  CAGTAAATATGAGTTTTGATCATCCTGAGAAAAATGGGCCTTGGCCTGCAGACCCAATAA
  ACCTTCCCTCCCATGGATAATAGTGCTAATTCCTGAGGACCTGAAGGGCCTGCCGCCCCT
  GGGGGATTAGCCAGAAGCAGGCTTGTTTTCCTGCTCAGAACAAAGTGACTTCCCTGAACA
  CATCTTCATTATGATTCACACCAACCTGAAGAAAAAGTTCAGCTGCTGCGTCCTGGTCTT
  TCTTCTGTTTGCAGTCATCTGTGTGTGGAAGGAAAAGAAGAAAGGGAGTTACTATGATTC
  CTTTAAATTGCAAACCAAGGAATTCCAGGTGTTAAAGAGTCTGGGGAAATTGGCCATGGG
  GTCTGATTCCCAGTCTGTATCCTCAAGCAGCACCCAGGACCCCCACAGGGGCCGCCAGAC
  CCTCGGCAGTCTCAGAGGCCTAGCCAAGGCCAAACCAGAGGCCTCCTTCCAGGTGTGGAA
  CAAGGACAGCTCTTCCAAAAACCTTATCCCTAGGCTGCAAAAGATCTGGAAGAATTACCT
  AAGCATGAACAAGTACAAAGTGTCCTACAAGGGGCCAGGACCAGGCATCAAGTTCAGTGC
  AGAGGCCCTGCGCTGCCACCTCCGGGACCATGTGAATGTATCCATGGTAGAGGTCACAGA
  TTTTCCCTTCAATACCTCTGAATGGGAGGGTTATCTGCCCAAGGAGAGCATTAGGACCAA
  GGCTGGGCCTTGGGGCAGGTGTGCTGTTGTGTCGTCAGCGGGATCTCTGAAGTCCTCCCA
  ACTAGGCAGAGAAATCGATGATCATGACGCAGTCCTGAGGTTTAATGGGGCACCCACAGC
  CAACTTCCAACAAGATGTGGGCACAAAAACTACCATTCGCCTGATGAACTCTCAGTTGGT
  TACCACAGAGAAGCGCTTCCTCAAAGACAGTTTGTACAATGAAGGAATCCTAATTGTATG
  GGACCCATCTGTATACCACTCAGATATCCCAAAGTGGTACCAGAATCCGGATTATAATTT
  CTTTAACAACTACAAGACTTATCGTAAGCTGCACCCCAATCAGCCCTTTTACATCCTCAA
  GCCCCAGATGCCTTGGGAGCTATGGGACATTCTTCAAGAAATCTCCCCAGAAGAGATTCA
  GCCAAACCCCCCATCCTCTGGGATGCTTGGTATCATCATCATGATGACGCTGTGTGACCA
  GGTGGATATTTATGAGTTCCTCCCATCCAAGCGCAAGACTGACGTGTGCTACTACTACCA
  GAAGTTCTTCGATAGTGCCTGCACGATGGGTGCCTACCACCCGCTGCTCTATGAGAAGAA
  TTTGGTGAAGCATCTCAACCAGGGCACAGATGAGGACATCTACCTGCTTGGAAAAGCCAC
  ACTGCCTGGCTTCCGGACCATTCACTGCTAAGCACAGGCTCCTCACTCTTCTCCATCAGG
  CATTAAATGAATGGTCTCTTGGCCACCCCAGCCTGGGAAGAACATTTTCCTGAACAATTC
  CAGCCTGCTCCTTTTACTCTAGGGGCCTCTGTCAGCAAGACCATGGGGGCTTCAAGAGCC
  TGTGGTCAGGAAATCAGGTCCAGCCTTCCCTGTAGCCAGACAGTTTATGAGCCCAGAGCC
  TCCTGCCACACACATGCACACATATCTAGCATTCTTTCCAGACAGCATCCTCCCCGCCTT
  CCACCTTGGTAGATGCAAGGTCTATCTCTCCCATCAGGGCTGCCAAAGCTGGGCTTTGTT
  TTTCCCAGCAGAATGATGCCATTCTCACAAACCAATGCTCTATATTGCTTGAAGTCTGCA
  TCTAAATATTGATTTCACGTTTTAAAGAAATTCTCTTAAATTACAATTGTGCCCAATGCA
  GGGTGGCTCTGGGGGGCAAGTAGGTGGTACAGGGGATTGGAAACATGCTCCGCGCCTCCA
  GAGAAAAGTTGCTCCCGAGGTCCATGCCCCTGGAACGTGTTCCTATCACTCTGGCTGGTT
  GGGCTGGTCCTTAGACTGGGTGCTTATGATTAAAGGGTCTTGGTTAGCCCACTTTCCCTC
  TCCATGTGGAGATGGAAGGTAGAGAAGGATACAGTGTCTATCCTCAAGTTGCTACGGTTC
  AGTGAGAGAGGCAGACATCTGAACAGGCAGGTAGGATTCAGTGTGCTCAGTGCACTGGGG
  ATTTGGAGAGAGATGGGCTTGCTCTCTCTGTGCACCCAGGAGGGCCACGCACTTAAAACT
  GTGTTTGTGGATCAGAGAAGGCTTTATAGCACAGGGGGCATTCAGATGAGTCTTAGAGGA
  AGAGAAGAAACATGGCAAGCAGATTACATCTGAGCCGTTTGAATTGTGTTTTTCTTTCTT
  CCCATGTTTATTTTCTAAGATCTACCTGAACTTAGAGACTCAAGATATTTTTTTAGGAAA
  CCTCCTACCCATGTCTGAGGTAGCAAGTGCAGCCTCACGACAGATACCAGGCAATCCAGA
  GCCACAAAACGTGATTCCTCCAGGCTCTGCCTGGCCTGACCCTGTCCTGTCAGCTGGGTT
  TACATACCAGTCCCATTCTTCCTTTTCAATACCTACCCCCAAATCTTCTCCTAACCACCA
  TCTGTTTTTTTTTTTTAAAGCATTTTTTGCTTTAAAAGCATCCTGACCCCAATTTCTTTG
  AGCTCACGGGCCTTTTGCTGAAGGTCTCTCAGGGTGTAGTGGTGTGGCTCTCTGGACTTA
  ACGTCACTCTCAGAGGTCAGAACCTTGGAGATCAGAACTGATTCTCACCAGGTGTGAGAG
  GTGTGGTAGCAGATTGCAATGCTCTGCACCTCTTCCTTGCAAGTGAGCAACTTCAGGCTC
  TCTGGGCAGAGGCTGGCCCACTGTAGTTTGCAGACATGCTCTCCAGATGGTTTTACTAAG
  TCCCCTCTCCCTGATAGGGAATCCTGCTGGACCAGCGCAGCCCTGGTGTGGAGAGGTTAA
  AAGACTTGCACAGGATCACCAAGTCATGCTGTAGAGCCAGGATTCCTAGACCCAGGGCTC
  TGCACTCTCAAGGCTGGCCCCATGTGCTCAAGGGGGTCTAATGTTTGGGCTCCAAACTAA
  CCATCTCGGAGCTGGGCTCCTCATTTACTGCCAAACCCTCAGCTTATGTAGCTAGAAAGG
  GCCCTGGAGTGAGAAAGCCTGGATTTTCAAATTGATGCTCCCCTACTGACTAGCTGTGCC
  ACTCTGGGCAAATGCTCTTCCTTGAGCCTGTTTCCACACCTGTAAAGTGGGGATGATGAT
  CCTATCTCACTGCTTTTGTGAGGATTACAGGAAAGCACCTGTCCTGGCTCTGTACCTGGC
  ACGTAGTAGGTGCTCAGTTCATGCTGGTTTCCTTCCTGCCTTTAGTAGGGACCTGCTCTG
  TGCTCACACCTCGGCTGCATGCACCCTGCTGTGACGGAGGCTAGTGTGGAAGAGGTCCTG
  TCCTCAGGGAATTAACTGTCTTATTGGGAGACAACAACTGTCCTCCTTGGAACACCCAAG
  AAACCATGCAAAGCAGTGGACAACACAGAACACGCCCTCCTCCTCGCTGCCTGCAGCTCC
  AATCTGATTCTGCTTGGGAATGGGCGGAGCACGTGGGCTGCTTAACTGCTGTATAGGACA
  AGCCCCTTACCCCTCTCTGGGCCCATGAATTCCTGGCTTGGTTTATGTTCTGATTTGACA
  CACTGATTTTAATCTTCGAATCATGACACTGAGTGCAGAGGAGGTGGCATTCCGACAGCA
  GGACATACATGTTGGTGTGAAGACTGGGACGACACTGGGTAGAATCTAGTTTTTAATTAT
  TATTAATATAAAGGATCAAATTAATTTAAATATGATTCTGAAGTCTACAGAACTTTTAGT
  TCTGTGCTGTCTATGTGGACACTTTGGTAAAATGCAAATTATGATATGGACGTTATCATT
  GGTCTGGTGAGATGTTTCATATTTGTGACAGTTAATTTAAAAATTATGACTTAATGCTGC
  CTGTGTCTATGGGGTTCTGTCTTCTTTGATAGCCATCTATTCATCTGGATCATGGGACCC
  TCTCTAATCCTTCCACCAATCAAATAAGCTATTGCTATTGGTTTGGAGTTGAGATATCAG
  TCTCGGAAACTTCTGAAAAATGCTAATAATTACCCAAGGATTATGTCAAATTTTAAAATA
  AATGTGTGTGTGTTTCTTTAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_003032
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003032.2, NP_003023.1
• RefSeq Size: 4295 bp
• RefSeq ORF: 1221 bp
• Locus ID: 6480
• Cytogenetics: 3q27.3
• Domains: Glyco_transf_29
• Protein Families: Secreted Protein
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• Gene Summary: 'This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]'
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. The promoter and 5' terminal exon sequence is from an endogenous retroviral LTR (PMID: 8724135). Variant 2 is expressed in mature B lymphocytes and variants 1, 2 and 4 encode the same protein (isoform a).