KREMEN1 (NM_001039571) Human Untagged Clone

CAT#: SC322731

KREMEN1 (untagged)-Human kringle containing transmembrane protein 1 (KREMEN1), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KREMEN1
• Synonyms: FLJ31863; KREMEM1; KREMEN; kringle-coding gene marking the eye and the nose; kringle-containing transmembrane protein 1; kringle containing transmembrane protein 1; KRM1; OTTHUMP00000028977
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322731 CGGACGCGTGGGCGCGCTGCCCCCTTTACCCCGGGCCGCGCCCCGGGGCCCCGCACTGAC
  GGCCCATGGCGCCGCCCGCCGCCCGCCTCGCCCTGCTCTCCGCCGCGGCGCTCACGCTGG
  CGGCCCGGCCCGCGCCTAGCCCCGGCCTCGGCCCCGGACCCGAGTGTTTCACAGCCAATG
  GTGCGGATTATAGGGGAACACAGAACTGGACAGCACTACAAGGCGGGAAGCCATGTCTGT
  TTTGGAACGAGACTTTCCAGCATCCATACAACACTCTGAAATACCCCAACGGGGAGGGGG
  GCCTGGGTGAGCACAACTATTGCAGAAATCCAGATGGAGACGTGAGCCCCTGGTGCTATG
  TGGCAGAGCACGAGGATGGTGTCTACTGGAAGTACTGTGAGATACCTGCTTGCCAGATGC
  CTGGAAACCTTGGCTGCTACAAGGATCATGGAAACCCACCTCCTCTAACTGGCACCAGTA
  AAACGTCCAACAAACTCACCATACAAACTTGCATCAGTTTTTGTCGGAGTCAGAGGTTCA
  AGTTTGCTGGGATGGAGTCAGGCTATGCTTGCTTCTGTGGAAACAATCCTGATTACTGGA
  AGTACGGGGAGGCAGCCAGTACCGAATGCAACAGCGTCTGCTTCGGGGATCACACCCAAC
  CCTGTGGTGGCGATGGCAGGATCATCCTCTTTGATACTCTCGTGGGCGCCTGCGGTGGGA
  ACTACTCAGCCATGTCTTCTGTGGTCTATTCCCCTGACTTCCCCGACACCTATGCCACGG
  GGAGGGTCTGCTACTGGACCATCCGGGTTCCGGGGGCCTCCCACATCCACTTCAGCTTCC
  CCCTATTTGACATCAGGGACTCGGCGGACATGGTGGAGCTTCTGGATGGCTACACCCACC
  GTGTCCTAGCCCGCTTCCACGGGAGGAGCCGCCCACCTCTGTCCTTCAACGTCTCTCTGG
  ACTTCGTCATCTTGTATTTCTTCTCTGATCGCATCAATCAGGCCCAGGGATTTGCTGTTT
  TATACCAAGCCGTCAAGGAAGAACTGCCACAGGAGAGGCCCGCTGTCAACCAGACGGTGG
  CCGAGGTGATCACGGAGCAGGCCAACCTCAGTGTCAGCGCTGCCCGGTCCTCCAAAGTCC
  TCTATGTCATCACCACCAGCCCCAGCCACCCACCTCAGACTGTCCCAGGATGGACAGTCT
  ATGGTCTGGCAACTCTCCTCATCCTCACAGTCACAGCCATTGTAGCAAAGATACTTCTGC
  ACGTCACATTCAAATCCCATCGTGTTCCTGCTTCAGGGGACCTTAGGGATTGTCATCAAC
  CAGGGACTTCGGGGGAAATCTGGAGCATTTTTTACAAGCCTTCCACTTCAATTTCCATCT
  TTAAGAAGAAACTCAAGGGTCAGAGTCAACAAGATGACCGCAATCCCCTTGTGAGTGACT
  AAAAACCCCACTGTGCCTAGGACTTGAGGTCCCTCTTTGAGCTCAAGGCTGCCGTGGTCA
  ACCTCTCCTGTGGTTCTTCTCTGACAGACTCTTCCCCTCCTCTCCCTCTGCCTCGGCCTC
  TTCGGGGAAACCCTCCTCCTACAGACTAGGAAGAGGCACCCTGCTGCCAGGGCAGGCAGA
  GCCTGGATTCCTCCTGCTTCATCGATTGCACTTAGGAGAGAGACTCAAAGCCCTGGGGCC
  CGGCCCTCTCTGCATCTCTCTCTGATCTAGCTAGCAGTGGGGGTGTCAGGACAGTGAGGC
  TGAGATGACAGAGGTGGTCATGGCTGGCACAGGGCTCAGGTACATTCTAGATGGCTGTCA
  GGTGGTGGGTAGCTTTAGTTACATTGAATTTTTCTTGCTTCTCTATTTTTGTCCACACAC
  AAATCAGTTTCTCCTGATCTTTATGTCTTGGAACAGGGCCAGACAGGGAGAACTCTCAGG
  TACTCTTGGGAGTTGGTCCCATACAAGTGCGGACTCCTGGACATTAGCGAGGTGTAAAGA
  GGGCAGTGTCTGTGCTGCCCCGGCAGCTTTGCTCTCCAGATGCTGGACTAGGGTGGGCCT
  CCTTCAGCCTGGGAGGGTCTGAGAATAAGATCTAGTGACCCCCATTTATATCAAACCTGA
  TACCTTACACATGGGCTTCTTTCTAGATTCTTCTTTCCATAGCTCATGGAGCTGCAGGGA
  AAGCTTTAAGAGCTTTGGTCATATAAAACATCCATTCAGCTGGGCGCGATGGCTCATGCC
  TGTAATCCCAGCACTGTGGGAGGCTGAGGCGGGCAGATCACCTGAGGTCAGGAGTTCGAG
  ACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATATAAAAATTAGTCAGGC
  GTGGTGGCAGGCGCCTGTAATCCCAGCTACTCAGAAGGCTGAGACAGAAGAACAGCTTGA
  ACCCAGGAGGCTGAGATTGCAGTGAGCCGAGATCGCACCACTGCACTCCAGCCTGGGTGA
  CAAGAGTGAGACTCTGTCTCAAAAAAACAAAACACAAATAAACAAAAAAAATCCATTCAT
  TTACTCATGCAATAAATTCTCCTGCAAGCTTTTATGGGCACTCAGTAAGTACTCAGGATT
  GGCTTTATCAGCCTTGCCACTGAGCAGCTCATGGTCCTATGGAACCTGAGCCAGGCCTCA
  GTCTCTCCATGATTGGCTCAGCTAACTCTCAGTTCAGAGTGGAGAGTATCAATCTTGTGT
  TTTTGCCCTTAGGCAGCACTATATGAGACATGGGGCCTGTGGTCCTTCCTTCTGGTGTCC
  CCCGTGTTAAAAGATAAAAAACACCCCAAGGGCCGGGCGCGGTGGCTCATGCCTGTAATC
  CCAGCACTTTGGGAGGCTGAGGCGGGTGGATCACGAGGTCAGGTGATCGAAACCATCCTG
  GCTAAGACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGTGTGGTGGT
  GGGCGCCTGTAGTCCCAGCTGCTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGA
  GGCGGAGCTTGCAGTGAGCAGAGATCACGCCACTGCACTCCAGCCTGGGTGACAGTGCAA
  GACTCTGTCTCAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322731 unedited
  GTGCTGATTTTCGTACATTGTATACGACTCCTATAGGGCGGGAGGAAAACGCGGCGCGCC
  GGTACCGGTCCGGAATGCCCGGGATATCGTCGACCCACGCGTCCGCGGACGCGTGGGCGC
  GCTGCCCCCTTTACCCCGGGCCGCGCCCCGGGGCCCCGCACTGACGGCCCATGGCGCCGC
  CCGCCGCCCGCCTCGCCCTGCTCTCCGCCGCGGCGCTCACGCTGGCGGCCCGGCCCGCGC
  CTAGCCCCGGCCTCGGCCCCGGACCCGAGTGTTTCACAGCCAATGGTGCGGATTATAGGG
  GAACACAGAACTGGACAGCACTACAAGGCGGGAAGCCATGTCTGTTTTGGAACGAGACTT
  TCCAGCATCCATACAACACTCTGAAATACCCCAACGGGGAGGGGGGCCTGGGTGAGCACA
  ACTATTGCAGAAATCCAGATGGAGACGTGAGCCCCTGGTGCTATGTGGCAGAGCACGAGG
  ATGGTGTCTACTGGAAGTACTGTGAGATACCTGCTTGCCAGATGCCTGGAAACCTTGGCT
  GCTACAAGGATCATGGAAACCCACCTCCTCTAACTGGCACCAGTAAAACGTCCAACAAAC
  TCACCATACAAAACTTGCATCAGTTTTTTGTCGGAGTCAGAGGTTCAAGTTTGCTGGGAT
  GGGAGTCAGGCTATGCTTTGCTTCTGTGGAAACAATCCTGATTACTGAAAGTACGGGGGA
  GGGCAGCCAGTACCGGAATGCAACAGCGTCTGCTTCCGGGATCACACCCAACCCTGTCGT
  GCCGATGGCAGATCATCCCTCTTTGATACTCTCGTTGTGCCGCCTTGCGGTGGGAACTAC
  TCAGACAATGTCTTCCTGTGTCTTATCCCTGACTCCTCGAACCCTATGCCACGGGAGGTT
  CTGGCTACTGGAACATTCGAGTTAGGGCTTGCCAATCAACTTACGCCTGCGCATAGTGAC
  ACATG
• Restriction Sites: Please inquire
• ACCN: NM_001039571
• ORF Size: 1377 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001039571.1, NP_001034660.1
• RefSeq Size: 6115
• RefSeq ORF: 1377
• Locus ID: 83999
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (4) differs in the 3' UTR, uses an alternate terminal exon, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 2. The resulting isoform (4) has a distinct C-terminus and is shorter than isoform 2.