Lubricin (PRG4) (NM_001127709) Human Untagged Clone

CAT#: SC323275

PRG4 (untagged)-Human proteoglycan 4 (PRG4), transcript variant C

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PRG4
• Synonyms: CACP; HAPO; JCAP; MSF; SZP
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001127709, the custom clone sequence may differ by one or more nucleotides
  ATGGCATGGAAAACACTTCCCATTTACCTGTTGTTGCTGCTGTCTGTTTTCGTGATTCAG
  CAAGTTTCATCTCAAGATTTATCAAGCTGTGCAGGGAGATGTGGGGAAGGGTATTCTAGA
  GATGCCACCTGCAACTGTGATTATAACTGTCAACACTACATGGAGTGCTGCCCTGATTTC
  AAGAGAGTCTGCACTGCGGAGCTTTCCTGTAAAGGCCGCTGCTTTGAGTCCTTCGAGAGA
  GGGAGGGAGTGTGACTGCGACGCCCAATGTAAGAAGTATGACAAGTGCTGTCCCGATTAT
  GAGAGTTTCTGTGCAGAAGTAAAAGATAACAAGAAGAACAGAACTAAAAAGAAACCTACC
  CCCAAACCACCAGTTGTAGATGAAGCTGGAAGTGGATTGGACAATGGTGACTTCAAGGTC
  ACAACTCCTGACACGTCTACCACCCAACACAATAAAGTCAGCACATCTCCCAAGATCACA
  ACAGCAAAACCAATAAATCCCAGACCCAGTCTTCCACCTAATTCTGATACATCTAAAGAG
  ACGTCTTTGACAGTGAATAAAGAGACAACAGTTGAAACTAAAGAAACTACTACAACAAAT
  AAACAGACTTCAACTGATGGAAAAGAGAAGACTACTTCCGCTAAAGAGACACAAAGTATA
  GAGAAAACATCTGCTAAAGATTTAGCACCCACATCTAAAGTGCTGGCTAAACCTACACCC
  AAAGCTGAAACTACAACCAAAGGCCCTGCTCTCACCACTCCCAAGGAGCCCACGCCCACC
  ACTCCCAAGGAGCCTGCATCTACCACACCCAAAGAGCCCACACCTACCACCATCAAGTCT
  GCACCCACCACCCCCAAGGAGCCTGCACCCACCACCACCAAGTCTGCACCCACCACTCCC
  AAGGAGCCTGCACCCACCACCACCAAGGAGCCTGCACCCACCACTCCCAAGGAGCCTGCA
  CCCACCACCACCAAGGAGCCTGCACCCACCACCACCAAGTCTGCACCCACCACTCCCAAG
  GAGCCTGCACCCACCACCCCCAAGAAGCCTGCCCCAACTACCCCCAAGGAGCCTGCACCC
  ACCACTCCCAAGGAGCCTACACCCACCACTCCCAAGGAGCCTGCACCCACCACCAAGGAG
  CCTGCACCCACCACTCCCAAAGAGCCTGCACCCACTGCCCCCAAGAAGCCTGCCCCAACT
  ACCCCCAAGGAGCCTGCACCCACCACTCCCAAGGAGCCTGCACCCACCACCACCAAGGAG
  CCTTCACCCACCACTCCCAAGGAGCCTGCACCCACCACCACCAAGTCTGCACCCACCACT
  ACCAAGGAGCCTGCACCCACCACTACCAAGTCTGCACCCACCACTCCCAAGGAGCCTTCA
  CCCACCACCACCAAGGAGCCTGCACCCACCACTCCCAAGGAGCCTGCACCCACCACCCCC
  AAGAAGCCTGCCCCAACTACCCCCAAGGAGCCTGCACCCACCACTCCCAAGGAACCTGCA
  CCCACCACCACCAAGAAGCCTGCACCCACCACTCCCAAAGAGCCTGCCCCAACTACCCCC
  AAGGAGACTGCACCCACCACCCCCAAGAAGCTCACGCCCACCACCCCCGAGAAGCTCGCA
  CCCACCACCCCTGAGAAGCCCGCACCCACCACCCCTGAGGAGCTCGCACCCACCACCCCT
  GAGGAGCCCACACCCACCACCCCTGAGGAGCCTGCTCCCACCACTCCCAAGGCAGCGGCT
  CCCAACACCCCTAAGGAGCCTGCTCCAACTACCCCTAAGGAGCCTGCTCCAACTACCCCT
  AAGGAGCCTGCTCCAACTACCCCTAAGGAGACTGCTCCAACTACCCCTAAAGGGACTGCT
  CCAACTACCCTCAAGGAACCTGCACCCACTACTCCCAAGAAGCCTGCCCCCAAGGAGCTT
  GCACCCACCACCACCAAGGAGCCCACATCCACCACCTGTGACAAGCCCGCTCCAACTACC
  CCTAAGGGGACTGCTCCAACTACCCCTAAGGAGCCTGCTCCAACTACCCCTAAGGAGCCT
  GCTCCAACTACCCCTAAGGGGACTGCTCCAACTACCCTCAAGGAACCTGCACCCACTACT
  CCCAAGAAGCCTGCCCCCAAGGAGCTTGCACCCACCACCACCAAGGGGCCCACATCCACC
  ACCTCTGACAAGCCTGCTCCAACTACACCTAAGGAGACTGCTCCAACTACCCCCAAGGAG
  CCTGCACCCACTACCCCCAAGAAGCCTGCTCCAACTACTCCTGAGACACCTCCTCCAACC
  ACTTCAGAGGTCTCTACTCCAACTACCACCAAGGAGCCTACCACTATCCACAAAAGCCCT
  GATGAATCAACTCCTGAGCTTTCTGCAGAACCCACACCAAAAGCTCTTGAAAACAGTCCC
  AAGGAACCTGGTGTACCTACAACTAAGACTCCTGCAGCGACTAAACCTGAAATGACTACA
  ACAGCTAAAGACAAGACAACAGAAAGAGACTTACGTACTACACCTGAAACTACAACTGCT
  GCACCTAAGATGACAAAAGAGACAGCAACTACAACAGAAAAAACTACCGAATCCAAAATA
  ACAGCTACAACCACACAAGTAACATCTACCACAACTCAAGATACCACACCATTCAAAATT
  ACTACTCTTAAAACAACTACTCTTGCACCCAAAGTAACTACAACAAAAAAGACAATTACT
  ACCACTGAGATTATGAACAAACCTGAAGAAACAGCTAAACCAAAAGACAGAGCTACTAAT
  TCTAAAGCGACAACTCCTAAACCTCAAAAGCCAACCAAAGCACCCAAAAAACCCACTTCT
  ACCAAAAAGCCAAAAACAATGCCTAGAGTGAGAAAACCAAAGACGACACCAACTCCCCGC
  AAGATGACATCAACAATGCCAGAATTGAACCCTACCTCAAGAATAGCAGAAGCCATGCTC
  CAAACCACCACCAGACCTAACCAAACTCCAAACTCCAAACTAGTTGAAGTAAATCCAAAG
  AGTGAAGATGCAGGTGGTGCTGAAGGAGAAACACCTCATATGCTTCTCAGGCCCCATGTG
  TTCATGCCTGAAGTTACTCCCGACATGGATTACTTACCGAGAGTACCCAATCAAGGCATT
  ATCATCAATCCCATGCTTTCCGATGAGACCAATATATGCAATGGTAAGCCAGTAGATGGA
  CTGACTACTTTGCGCAATGGGACATTAGTTGCATTCCGAGGTCATTATTTCTGGATGCTA
  AGTCCATTCAGTCCACCATCTCCAGCTCGCAGAATTACTGAAGTTTGGGGTATTCCTTCC
  CCCATTGATACTGTTTTTACTAGGTGCAACTGTGAAGGAAAAACTTTCTTCTTTAAGGAT
  TCTCAGTACTGGCGTTTTACCAATGATATAAAAGATGCAGGGTACCCCAAACCAATTTTC
  AAAGGATTTGGAGGACTAACTGGACAAATAGTGGCAGCGCTTTCAACAGCTAAATATAAG
  AACTGGCCTGAATCTGTGTATTTTTTCAAGAGAGGTGGCAGCATTCAGCAGTATATTTAT
  AAACAGGAACCTGTACAGAAGTGCCCTGGAAGAAGGCCTGCTCTAAATTATCCAGTGTAT
  GGAGAAACGACACAGGTTAGGAGACGTCGCTTTGAACGTGCTATAGGACCTTCTCAAACA
  CACACCATCAGAATTCAATATTCACCTGCCAGACTGGCTTATCAAGACAAAGGTGTCCTT
  CATAATGAAGTTAAAGTGAGTATACTGTGGAGAGGACTTCCAAATGTGGTTACCTCAGCT
  ATATCACTGCCCAACATCAGAAAACCTGACGGCTATGATTACTATGCCTTTTCTAAAGAT
  CAATACTATAACATTGATGTGCCTAGTAGAACAGCAAGAGCAATTACTACTCGTTCTGGG
  CAGACCTTATCCAAAGTCTGGTACAACTGTCCT
  
• Restriction Sites: Please inquire
• ACCN: NM_001127709
• ORF Size: 3936 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001127709.1, NP_001121181.1
• RefSeq Size: 4780
• RefSeq ORF: 3936
• Locus ID: 10216
• Gene Summary: The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
  Transcript Variant: This variant (C, also known as V2) lacks two alternate in-frame exons in the 5' coding region, compared to variant A. The resulting protein (isoform C) is shorter than isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments.