PARVB (NM_013327) Human Untagged Clone

CAT#: SC324009

PARVB (untagged)-Human parvin, beta (PARVB), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PARVB
• Synonyms: CGI-56
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_013327.3 TGCGCCCGCCGCCGGCCCCACGCGCGGCCCATGTCCTCCGCGCCGCGCTCGCCCACCCCG
  CGGCCCCGCAGGATGAAGAAGGACGAGTCGTTCCTGGGCAAGCTGGGCGGCACCCTGGCC
  AGGAAGCGGAGGGCGCGCGAGGTGAGTGACCTGCAGGAAGAAGGCAAGAATGCCATCAAC
  TCACCGATGTCCCCCGCCCTGGCGGATGTTCACCCTGAAGACACCCAGCTCGAGGAGAAC
  GAGGAGCGCACGATGATTGACCCCACTTCCAAGGAAGACCCCAAGTTCAAGGAACTGGTC
  AAGGTCCTCCTCGACTGGATTAATGACGTGCTGGTGGAGGAGAGGATCATTGTGAAGCAG
  CTGGAGGAAGACCTGTATGACGGCCAGGTGCTGCAGAAGCTCTTGGAAAAACTGGCAGGG
  TGCAAGCTGAATGTGGCTGAGGTGACACAGTCCGAAATAGGGCAGAAACAGAAGCTGCAG
  ACGGTGCTGGAAGCAGTACATGACCTGCTGCGGCCCCGAGGCTGGGCGCTCCGGTGGAGC
  GTGGACTCAATTCACGGGAAGAACCTGGTGGCCATCCTCCACCTGCTGGTCTCTCTGGCC
  ATGCACTTCAGGGCCCCCATCCGCCTTCCTGAGCATGTAACGGTGCAGGTGGTGGTCGTG
  CGGAAACGGGAAGGCCTGCTGCATTCCAGCCACATCTCGGAGGAGCTGACCACAACTACA
  GAGATGATGATGGGCCGGTTCGAGCGGGATGCCTTCGACACGCTGTTCGACCACGCCCCG
  GATAAGCTCAGCGTGGTGAAGAAGTCTCTCATCACTTTTGTGAACAAGCACCTGAACAAG
  CTGAATTTGGAGGTGACGGAACTGGAGACCCAGTTTGCAGATGGCGTGTACCTGGTTCTG
  CTCATGGGCCTTCTGGAAGACTACTTTGTTCCTCTCCACCACTTCTACCTGACTCCGGAA
  AGCTTCGATCAGAAGGTCCACAATGTGTCCTTTGCCTTTGAGCTGATGCTGGACGGAGGC
  CTCAAGAAACCCAAGGCTCGTCCTGAAGACGTGGTTAACTTGGACCTCAAATCCACCCTG
  AGGGTTCTTTACAACCTGTTCACCAAGTACAAGAACGTGGAGTGACGGGGGAGCTGTGGA
  TGGTGGCAGGAGTGTCCCAGCAAGAAAGGCGGCATCCGTCTGTGCCCTGTGCCTTTCCAG
  GGAGCCAGGCGCCATGGGCTTCTGGTCCAAGCTGTGTTGACTGTCATCCCCACCCCACCC
  CTACCTCACGCCTGCCCCACCCCCTGCCTCTTTTGGTTGTTGTTCTTAATCTCCTCTCCA
  TGTAGTTCCCAGTGGGCAAGAGCCTTTGAAAATGCAGGATTCTAAACACTCGTGCTTGCG
  TTTGAAGCCTCGCGTCACTCAGTCGCGTGGGATGATGAGTCCGTTGTTGTCTGCCTTGGC
  CGAAAGATGAAAAAAAGCCTGAACCCCAACCCCCAGCTGGTTGAGAGCACCCTGCATTCT
  GCCTCATGGTGCAGTTAGCGATCACAGGCCTTCAGAAGTACAACATCAGCTCAGCAGGAA
  CGCCGGCTCCCCGAGGACCCAGGCTTGACGATTCACCGGGGATCTCCTGGGCTGGGCTCT
  CCTTGGAAGTGAGGCCTTTTATTAAAAATAAAAGGGTTTTGCAGTTTGAAAAAAAAAAAA
  AAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013327.3 unedited
  GCTTGGTGCGATTGTATACGACTCCTATAGGGCGGCCGGCGAACGCGGCGCGCCGGTACC
  GGTCCGGAATTCCCGGGATTGCGCCCGCCGCCGGCCCCACGCGCGGCCCATGTCCTCCGC
  GCCGCGCTCGCCCACCCCGCGGCCCCGCAGGATGAAGAAGGACGAGTCGTTCCTGGGCAA
  GCTGGGCGGCACCCTGGCCAGGAAGCGGAGGGCGCGCGAGGTGAGTGACCTGCAGGAAGA
  AGGCAAGAATGCCATCAACTCACCGATGTCCCCCGCCCTGGCGGATGTTCACCCTGAAGA
  CACCCAGCTCGAGGAGAACGAGGAGCGCACGATGATTGACCCCACTTCCAAGGAAGACCC
  CAAGTTCAAGGAACTGGTCAAGGTCCTCCTCGACTGGATTAATGACGTGCTGGTGGAGGA
  GAGGATCATTGTGAAGCAGCTGGAGGAAGACCTGTATGACGGCCAGGTGCTGCAGAAGCT
  CTTGGAAAAACTGGCAGGGTGCAAGCTGAATGTGGCTGAGGTGACACAGTCCGAAATAGG
  GCAGAAACAGAAGCTGCAGACGGTGCTGGAAGCAGTACATGACCTGCTGCGGCCCCGAGG
  CTGGGCGCTCCGGTGGAGCGTGGACTCAATTCACGGGAAAGAACCTGGGTGGCCATTCCT
  CCACCTGCTGGTCCTCTCT
• Restriction Sites: ECoRI-NOT
• ACCN: NM_013327
• ORF Size: 1095 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_013327.3, NP_037459.2
• RefSeq Size: 1713
• RefSeq ORF: 1095
• Locus ID: 29780
• Domains: CH
• Protein Pathways: Focal adhesion
• Gene Summary: This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (2, also known as ParvB2) differs in the 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The resulting isoform (b) has a distinct and shorter N-terminus, compared to isoform a.