C1orf2 (FAM189B) (NM_198264) Human Untagged Clone

CAT#: SC324099

FAM189B (untagged)-Human family with sequence similarity 189, member B (FAM189B), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FAM189B
• Synonyms: C1orf2; COTE1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_198264.1 AAAGGACGGGGCCTTGGGCGCCTCTGAGATGCTCCCAAGTGCCAGGGAGGGCCGAGCGAG
  GCGCAGGCAACCGGGCAGCAGGCATGATGCCCTCGCCTAGTGACTCCAGCCGCTCGCTGA
  CCAGCCGGCCCAGCACCAGGGGCCTTACCCACCTCCGCCTCCACCGACCCTGGCTGCAGG
  CCCTGCTTACGCTGGGGCTGGTCCAAGTGCTCCTGGGCATCCTGGTGGTCACCTTCAGCA
  TGGTGGCCTCTTCCGTCACCACCACCGAGAGCATCAAGAGGTCCTGCCCGTCTTGGGCTG
  GGTTCTCGAACCTGCTCTTCAGCGTCTGTGGGCTCACCATTTGTGCCGCTATAATCTGTA
  CACTCTCTGCTATTGTCTGCTGCATCCAAATCTTCTCCCTGGACCTCGTGCATACGCTGG
  CCCCTGAGCGGTCAGTCTCAGGCCCACTGGGACCTCTGGGCTGCACGTCCCCGCCCCCAG
  CCCCTCTCCTACACACCATGCTGGACCTGGAGGAATTTGTCCCGCCTGTGCCCCCACCGC
  CCTACTATCCCCCAGAGTATACCTGCAGCTCAGAAACAGATGCACAGAGCATCACGTACA
  ATGGCTCCATGGACAGCCCAGTGCCCTTGTACCCTACCGATTGCCCCCCTTCTTATGAGG
  CAGTCATGGGACTACGAGGAGACAGCCAGGCCACTCTCTTTGACCCTCAGCTTCACGATG
  GCTCGTGCATCTGTGAACGAGTGGCCTCCATTGTAGACGTGTCCATGGACAGCGGGTCTC
  TGGTGCTGTCAGCCATTGGTGACCTCCCTGGGGGCTCTAGCCCGTCGGAGGACTCGTGCC
  TGCTGGAGCTGCAGGGCTCCGTGCGCTCCGTGGACTACGTTCTCTTTCGCTCCATCCAGC
  GCAGCCGTGCCGGCTACTGCCTCAGCCTGGACTGTGGCCTGCGGGGCCCCTTCGAGGAAA
  GCCCCCTGCCACGGCGCCCCCCACGGGCTGCCCGCTCCTATTCCTGCTCTGCCCCTGAAG
  CTCCACCCCCACTGGGTGCCCCCACAGCTGCCCGCAGCTGCCACCGGTTGGAGGGCTGGC
  CGCCCTGGGTGGGACCCTGCTTCCCCGAGCTGAGGCGGCGGGTCCCCCGGGGAGGGGGCC
  GCCCAGCCGCAGCCCCGCCCACCCGAGCCCCGACTCGTCGCTTCAGCGATAGCTCAGGTT
  CCCTCACCCCACCGGGGCACCGGCCTCCTCATCCGGCATCCCCACCACCGCTGCTGCTGC
  CACGGTCCCACAGCGACCCAGGCATCACGACCTCCAGTGACACTGCTGACTTCAGGGACC
  TTTATACCAAAGTGCTTGAGGAAGAAGCTGCTTCTGTTTCCTCTGCAGATACAGGGCTCT
  GCTCTGAAGCCTGCCTCTTCCGCCTAGCCCGCTGCCCTTCCCCCAAGTTGCTACGTGCCC
  GGTCAGCCGAGAAACGGCGCCCTGTGCCCACCTTCCAAAAAGTTCCCCTGCCCTCGGGCC
  CTGCACCTGCCCACTCCCTGGGGGACCTAAAGGGCAGCTGGCCAGGTCGGGGCCTGGTCA
  CTCGTTTCCTCCAGATATCCAGGAAAGCCCCAGACCCCAGTGGGACTGGAGCTCATGGAC
  ATAAGCAGGTGCCCCGGAGCCTGTGGGGCCGGCCTGGCCGAGAGAGCCTCCACCTTCGCA
  GCTGCGGAGATCTGAGCTCTAGCTCTTCCCTGCGGCGTCTCCTGTCTGGCCGCAGGCTGG
  AGCGTGGTACCCGCCCCCACAGCCTCAGCCTCAACGGGGGCAGCCGGGAGACTGGGCTCT
  GACCTAGGCTTCTTGTCACACTGAACACATCCAGCCACAGGCACCAGCTGGTTGGGACCA
  GCAGCCCCCAGCATCCTCTTGCACTGGCTGGCACAAAAAGAAACCTGCTGTATACCCCCC
  AAAGTGTCCCTTTCCCTCCTACCTCTGGGGTCTCTTGCTGCTTGCCTCTGCTGCTCTGGA
  CTGGGAGAGCTTCTGTCCTGTGCTGCATGGGTATTTAGACTGTGGGGGAGATGCCCCTTC
  TTATAGCACTGGAGGAGGAAAACAAATTCTTGTCCCCCTCAGAATGAGAGTGGCTCTTTC
  TGATTTGCAAGGGCACTATGGTCAGGGCAAAGGCATGGCCCAGGTGTTTAAGTACAGGGT
  GACGTGTGCCTATGCAATGGGGTGGTAAGGCAGGCACGAAGAGTCCAAAAAATCTAGGTG
  GCCTCTCAGCTCTGCCACCTCTAGCTGCATGACCTTGGGCAAGCTATGTAACCCCAATTG
  CCTGCTCCATTAAAGACTGTGAAGGTAGAATGTTTGTAAAGCTCTTAACAGTATGTAAGC
  CTTCAATAAATTTCAGTTTTCCCCTTGTTTTCTTGATCAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_198264.1 unedited
  GGCTATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGAAAGGACGGGGCCTTGGGCGCCTCTGA
  GATGCTCCCAAGTGCCAGGGAGGGCCGAGCGAGGCGCAGGCAACCGGGCAGCAGGCATGA
  TGCCCTCGCCTAGTGACTCCAGCCGCTCGCTGACCAGCCGGCCCAGCACCAGGGGCCTTA
  CCCACCTCCGCCTCCACCGACCCTGGCTGCAGGCCCTGCTTACGCTGGGGCTGGTCCAAG
  TGCTCCTGGGCATCCTGGTGGTCACCTTCAGCATGGTGGCCTCTTCCGTCACCACCACCG
  AGAGCATCAAGAGGTCCTGCCCGTCTTGGGCTGGGTTCTCGAACCTGCTCTTCAGCGTCT
  GTGGGCTCACCATTTGTGCCGCTATAATCTGTACACTCTCTGCTATTGTCTGCTGCATCC
  AAATCTTCTCCCTGGACCTCGTGCATACGCTGGCCCCTGAGCGGTCAGTCTCAGGCCCAC
  TGGGACCTCTGGGCTGCACGTCCCCGCCCCCAGCCCCTCTCCTACACACCATGCTGGACC
  TGGAGGAATTTGTCCCGCCTGTGCCCCCACCGCCCTACTATCCCCCAGAGTATACCTGCA
  GCTCAGAAACAGATGCACAGAGCATCACGTACAATGGCTCCATGGACAGCCCAGTGCCCT
  TGTACCCTACCGATTGCCCCCCTTCTTATGAGCAGTCATGGGACTACGAGGAGACAGCCA
  GGCCACTCTCTTTGACCCTCAGCTTCACGATGGCTCGTGCATCTGTGAACGAGTGCCTCA
  TTGTAGACGTGTCCATGGAACAGCGGTCTTCTGGTGCTGTCAGCCATTGTTGACCTCCCT
  GGGGCCTCTAGCCCGTCGAGACTCGTGCCTGCTGACTGCCAGGGCTCCGTGGCGCCCTCC
  GTGGAACATAACCGTTTCTCTTGCG
• Restriction Sites: ECoRI-NOT
• ACCN: NM_198264
• ORF Size: 1719 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_198264.1, NP_937995.1
• RefSeq Size: 2921
• RefSeq ORF: 1719
• Locus ID: 10712
• Protein Families: Transmembrane
• Gene Summary: This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (2) lacks an in-frame portion of the 5' coding region compared to variant 1. The resulting protein (isoform b) is shorter than isoform a.