CD162 (SELPLG) (NM_003006) Human Untagged Clone

CAT#: SC324184

SELPLG (untagged)-Human selectin P ligand (SELPLG), transcript variant 2


  "NM_003006" in other vectors (7)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Other products for "SELPLG"

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SELPLG
Synonyms CD162; CLA; PSGL-1; PSGL1
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_003006.3 CTCGGATCCGGGACTGCCGCAGGGGGTGCCACAGCAGTGCCTGGCAGCGTGGGCTGGGAC
CTTGTCACTAAAGCAGAGAAGCCACTTCTTCTGGGCCCACGAGGCAGCTGTCCCATGCTC
TGCTGAGCACGGTGGTGCCATGCCTCTGCAACTCCTCCTGTTGCTGATCCTACTGGGCCC
TGGCAACAGCTTGCAGCTGTGGGACACCTGGGCAGATGAAGCCGAGAAAGCCTTGGGTCC
CCTGCTTGCCCGGGACCGGAGACAGGCCACCGAATATGAGTACCTAGATTATGATTTCCT
GCCAGAAACGGAGCCTCCAGAAATGCTGAGGAACAGCACTGACACCACTCCTCTGACTGG
GCCTGGAACCCCTGAGTCTACCACTGTGGAGCCTGCTGCAAGGCGTTCTACTGGCCTGGA
TGCAGGAGGGGCAGTCACAGAGCTGACCACGGAGCTGGCCAACATGGGGAACCTGTCCAC
GGATTCAGCAGCTATGGAGATACAGACCACTCAACCAGCAGCCACGGAGGCACAGACCAC
TCCACTGGCAGCCACAGAGGCACAGACAACTCGACTGACGGCCACGGAGGCACAGACCAC
TCCACTGGCAGCCACAGAGGCACAGACCACTCCACCAGCAGCCACGGAAGCACAGACCAC
TCAACCCACAGGCCTGGAGGCACAGACCACTGCACCAGCAGCCATGGAGGCACAGACCAC
TGCACCAGCAGCCATGGAAGCACAGACCACTCCACCAGCAGCCATGGAGGCACAGACCAC
TCAAACCACAGCCATGGAGGCACAGACCACTGCACCAGAAGCCACGGAGGCACAGACCAC
TCAACCCACAGCCACGGAGGCACAGACCACTCCACTGGCAGCCATGGAGGCCCTGTCCAC
AGAACCCAGTGCCACAGAGGCCCTGTCCATGGAACCTACTACCAAAAGAGGTCTGTTCAT
ACCCTTTTCTGTGTCCTCTGTTACTCACAAGGGCATTCCCATGGCAGCCAGCAATTTGTC
CGTCAACTACCCAGTGGGGGCCCCAGACCACATCTCTGTGAAGCAGTGCCTGCTGGCCAT
CCTAATCTTGGCGCTGGTGGCCACTATCTTCTTCGTGTGCACTGTGGTGCTGGCGGTCCG
CCTCTCCCGCAAGGGCCACATGTACCCCGTGCGTAATTACTCCCCCACCGAGATGGTCTG
CATCTCATCCCTGTTGCCTGATGGGGGTGAGGGGCCCTCTGCCACAGCCAATGGGGGCCT
GTCCAAGGCCAAGAGCCCGGGCCTGACGCCAGAGCCCAGGGAGGACCGTGAGGGGGATGA
CCTCACCCTGCACAGCTTCCTCCCTTAGCTCACTCTGCCATCTGTTTTGGCAAGACCCCA
CCTCCACGGGCTCTCCTGGGCCACCCCTGAGTGCCCAGACCCCATTCCACAGCTCTGGGC
TTCCTCGGAGACCCCTGGGGATGGGGATCTTCAGGGAAGGAACTCTGGCCACCCAAACAG
GACAAGAGCAGCCTGGGGCCAAGCAGACGGGCAAGTGGAGCCACCTCTTTCCTCCCTCCG
CGGATGAAGCCCAGCCACATTTCAGCCGAGGTCCAAGGCAGGAGGCCATTTACTTGAGAC
AGATTCTCTCCTTTTTCCTGTCCCCCATCTTCTCTGGGTCCCTCTAACATCTCCCATGGC
TCTCCCCGCTTCTCCTGGTCACTGGAGTCTCCTCCCCATGTACCCAAGGAAGATGGAGCT
CCCCCATCCCACACGCACTGCACTGCCATTGTCTTTTGGTTGCCATGGTCACCAAACAGG
AAGTGGACATTCTAAGGGAGGAGTACTGAAGAGTGACGGACTTCTGAGGCTGTTTCCTGC
TGCTCCTCTGACTTGGGGCAGCTTGGGTCTTCTTGGGCACCTCTCTGGGAAAACCCAGGG
TGAGGTTCAGCCTGTGAGGGCTGGGATGGGTTTCGTGGGCCCAAGGGCAGACCTTTCTTT
GGGACTGTGTGGACCAAGGAGCTTCCATCTAGTGACAAGTGACCCCCAGCTATCGCCTCT
TGCCTTCCCCTGTGGCCACTTTCCAGGGTGGACTCTGTCTTGTTCACTGCAGTATCCCAA
CTGCAGGTCCAGTGCAGGCAATAAATATGTGATGGACAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAA
Restriction Sites ECoRI-NOT     
ACCN NM_003006
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_003006.3, NP_002997.1
RefSeq Size 2550 bp
RefSeq ORF 1209 bp
Locus ID 6404
Cytogenetics 12q24.11
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
Gene Summary 'This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]'
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1.

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.