Thymine DNA glycosylase (TDG) (NM_003211) Human Untagged Clone

CAT#: SC324192

TDG (untagged)-Human thymine-DNA glycosylase (TDG)


  "NM_003211" in other vectors (7)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TDG
Synonyms hTDG
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_003211.3 GGGGGACAGTAGAAGCCTGGAGGAGGAGCTTGAGTCCAGCCACTGTCTGGGTACTGCCAG
CCATCGGGCCCAGGTCTCTGGGGTTGTCTTACCGCAGTGAGTACCACGCGGTACTACAGA
GACCGGCTGCCCGTGTGCCCGGCAGGTGGAGCCGCCCGCATCAGCGGCCTCGGGGAATGG
AAGCGGAGAACGCGGGCAGCTATTCCCTTCAGCAAGCTCAAGCTTTTTATACGTTTCCAT
TTCAACAACTGATGGCTGAAGCTCCTAATATGGCAGTTGTGAATGAACAGCAAATGCCAG
AAGAAGTTCCAGCCCCAGCTCCTGCTCAGGAACCAGTGCAAGAGGCTCCAAAAGGAAGAA
AAAGAAAACCCAGAACAACAGAACCAAAACAACCAGTGGAACCCAAAAAACCTGTTGAGT
CAAAAAAATCTGGCAAGTCTGCAAAATCAAAAGAAAAACAAGAAAAAATTACAGACACAT
TTAAAGTAAAAAGAAAAGTAGACCGTTTTAATGGTGTTTCAGAAGCTGAACTTCTGACCA
AGACTCTCCCCGATATTTTGACCTTCAATCTGGACATTGTCATTATTGGCATAAACCCGG
GACTAATGGCTGCTTACAAAGGGCATCATTACCCTGGACCTGGAAACCATTTTTGGAAGT
GTTTGTTTATGTCAGGGCTCAGTGAGGTCCAGCTGAACCATATGGATGATCACACTCTAC
CAGGGAAGTATGGTATTGGATTTACCAACATGGTGGAAAGGACCACGCCCGGCAGCAAAG
ATCTCTCCAGTAAAGAATTTCGTGAAGGAGGACGTATTCTAGTACAGAAATTACAGAAAT
ATCAGCCACGAATAGCAGTGTTTAATGGAAAATGTATTTATGAAATTTTTAGTAAAGAAG
TTTTTGGAGTAAAGGTTAAGAACTTGGAATTTGGGCTTCAGCCCCATAAGATTCCAGACA
CAGAAACTCTCTGCTATGGTATGCCATCATCCAGTGCAAGATGTGCTCAGTTTCCTCGAG
CCCAAGACAAAGTTCATTACTACATAAAACTGAAGGACTTAAGAGATCAGTTGAAAGGCA
TTGAACGAAATATGGACGTTCAAGAGGTGCAATATACATTTGACCTACAGCTTGCCCAAG
AGGATGCAAAGAAGATGGCTGTTAAGGAAGAAAAATATGATCCAGGTTATGAGGCAGCAT
ATGGTGGTGCTTACGGAGAAAATCCATGCAGCAGTGAACCTTGTGGCTTCTCTTCAAATG
GGCTAATTGAGAGCGTGGAGTTAAGAGGAGAATCAGCTTTCAGTGGCATTCCTAATGGGC
AGTGGATGACCCAGTCATTTACAGACCAAATTCCTTCCTTTAGTAATCACTGTGGAACAC
AAGAACAGGAAGAAGAAAGCCATGCTTAAGAATGGTGCTTCTCAGCTCTGCTTAAATGCT
GCAGTTTTAATGCAGTTGTCAACAAGTAGAACCTCAGTTTGCTAACTGAAGTGTTTTATT
AGTATTTTACTCTAGTGGTGTAATTGTAATGTAGAACAGTTGTGTGGTAGTGTGAACCGT
ATGAACCTAAGTAGTTTGGAAGAAAAAGTAGGGTTTTTGTATACTAGCTTTTGTATTTGA
ATTAATTATCATTCCAGCTTTTTATATACTATATTTCATTTATGAAGAAATTGATTTTCT
TTTGGGAGTCACTTTTAATCTGTAATTTTAAAATACAAGTCTGAATATTTATAGTTGATT
CTTAACTGTGCATAAACCTAGATATACCATTATCCCTTTTATACCTAAGAAGGGCATGCT
AATAATTACCACTGTCAAAGAGGCAAAGGTGTTGATTTTTGTATATGAAGTTAAGCCTCA
GTGGAGTCTCATTTGTTAGTTTTTAGTGGTAACTAAGGGTAAACTCAGGGTTCCCTGAGC
TATATGCACACTCAGACCTCTTTGCTTTACCAGTGGTGTTTGTGAGTTGCTCAGTAGTAA
AAACTGGCCTTACCTGACAGAGCCCTGGCTTTGACCTGCTCAGCCCTGTGTGTTAATCCT
CTAGTAGCCAATTAACTACTCTGGGGTGGCAGGTTCCAGAGAATGCAGTAGACCTTTTGC
CACTCATCTGTGTTTTACTTGAGACATGTAAATATGATAGGGAAGGAACTGAATTTCTCC
ATTCATATTTATAACCATTCTAGTTTTATCTTCCTTGGCTTTAAGAGTGTGCCATGGAAA
GTGATAAGAAATGAACTTCTAGGCTAAGCAAAAAGATGCTGGAGATATTTGATACTCTCA
TTTAAACTGGTGCTTTATGTACATGAGATGTACTAAAATAAGTAATATAGAATTTTTCTT
GCTAGGTAAATCCAGTAAGCCAATAATTTTAAAGATTCTTTATCTGCATCATTGCTGTTT
GTTACTATAAATTAAATGAACCTCATGGAAAGGTTGAGGTGTATACCTTTGTGATTTTCT
AATGAGTTTTCCATGGTGCTACAAATAATCCAGACTACCAGGTCTGGTAGATATTAAAGC
TGGGTACTAAGAAATGTTATTTGCATCCTCTCAGTTACTCCTGAATATTCTGATTTCATA
CGTACCCAGGGAGCATGCTGTTTTGTCAATCAATATAAAATATTTATGAGGTCTCCCCCA
CCCCCAGGAGGTTATATGATTGCTCTTCTCTTTATAATAAGAGAAACAAATTCTTATTGT
GAATCTTAACATGCTTTTTAGCTGTGGCTATGATGGATTTTATTTTTTCCTAGGTCAAGC
TGTGTAAAAGTCATTTATGTTATTTAAATGATGTACTGTACTGCTGTTTACATGGACGTT
TTGTGCGGGTGCTTTGAAGTGCCTTGCATCAGGGATTAGGAGCAATTAAATTATTTTTTC
ACGGGACTGTGTAAAGCATGTAACTAGGTATTGCTTTGGTATATAACTATTGTAGCTTTA
CAAGAGATTGTTTTATTTGAATGGGGAAAATACCCTTTAAATTATGACGGACATCCACTA
GAGATGGGTTTGAGGATTTTCCAAGCGTGTAATAATGATGTTTTTCCTAACATGACAGAT
GAGTAGTAAATGTTGATATATCCTATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites ECoRI-NOT     
ACCN NM_003211
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_003211.3, NP_003202.3
RefSeq Size 3229 bp
RefSeq ORF 1233 bp
Locus ID 6996
Cytogenetics 12q23.3
Domains UDG
Protein Families Druggable Genome
Protein Pathways Base excision repair
Gene Summary 'The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]'

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.