Glycoprotein 2 (GP2) (NM_001007242) Human Untagged Clone

CAT#: SC324309

GP2 (untagged)-Human glycoprotein 2 (zymogen granule membrane) (GP2), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GP2
• Synonyms: ZAP75
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001007242.1 GCTGCATGGGAAGTCTGCATACAGCAAAGTGACCTGCATGCCTCACCTTATGGAAAGGAT
  GGTGGGCTCTGGCCTCCTGTGGCTGGCCTTGGTCTCCTGCATTCTGACCCAGGCATCTGC
  AGTGCAGCGAGACCCATCCACTGTGGAGGACAAGTGTGAGAAGGCCTGCCGCCCCGAGGA
  GGAGTGCCTTGCCCTCAACAGCACCTGGGGCTGTTTCTGCAGACAGGACCTCAATAGTTC
  TGATGTCCACAGTTTGCAGCCTCAGCTAGACTGTGGGCCCAGGGAGATCAAGGTGAAGGT
  GGACAAATGTTTGCTGGGAGGCCTGGGTTTGGGGGAGGAGGTCATTGCCTACCTGCGAGA
  CCCAAACTGCAGCAGCATCTTGCAGACAGAGGAGAGGAACTGGGTATCTGTGACCAGCCC
  CGTCCAGGCTAGTGCCTGCAGGAACATTCTGGAGAGAAATCAAACCCATGCCATCTACAA
  AAACACCCTCTCCTTGGTCAATGATTTCATCATCAGAGACACCATCCTCAACATCAACTT
  CCAATGTGCCTACCCACTGGACATGAAAGTCAGCCTCCAAGCTGCCTTGCAGCCCATTGT
  AAGTTCCCTGAACGTCAGTGTGGACGGGAATGGAGAGTTCATTGTCAGGATGGCCCTCTT
  CCAAGACCAGAACTACACGAATCCTTACCAAGGGGATGCAGTTGAACTGTCTGTTGAGTC
  CGTGCTGTATGTGGGTGCCATCTTGGAACAAGGGGACACCTCCCGGTTTAACCTGGTGTT
  GAGGAACTGCTATGCCACCCCCACTGAAGACAAGGCTGACCTTGTGAAGTATTTCATCAT
  CAGAAACAGCTGCTCAAATCAACGTGATTCCACCATCCACGTGGAGGAGAATGGGCAGTC
  CTCGGAAAGCCGGTTCTCAGTTCAGATGTTCATGTTTGCTGGACATTATGACCTAGTTTT
  CCTGCATTGTGAGATTCATCTCTGTGATTCTCTTAATGAACAGTGCCAGCCTTCTTGCTC
  AAGAAGTCAAGTCCGCAGTGAAGTACCGGCCATCGACCTAGCCCGGGTTCTAGATTTGGG
  GCCCATCACTCGGAGAGGTGCACAGTCTCCCGGTGTCATGAATGGAACCCCTAGCACTGC
  AGGGTTCCTGGTGGCCTGGCCTATGGTCCTCCTGACTGTCCTCCTGGCTTGGCTGTTCTG
  AGAGCTCCGCTGAGCATCTGGCCTTGAAGTTTGTGTTCTTCCCTCTGGCAATGGCTCCCT
  TCACCACTTCTGCTTTCCACTCCAATTCACACAGGCTTGGTATTAACAGAATCAAGGCCA
  GGCTAGGTTAGGAAAAGGGAAGAGCTTTCACCTTCTTTAAAACTCTCGGCTGGGCGCAGT
  GGCTCATGCCTGTAATCCCAGCATTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCA
  GCAGTTCAAAATCAGCCTGGCCAAAATGCTGAAACTCCGTCTCTACTAAAAATACAAAAA
  TTAGCCAGGCATGGTGGCAGGCGCCTGTAATCCCAGCTACTCGGGAGGCCAAGGCAGGAG
  AATTGCTCGAACTCAGGGGGTGGAGTTTGCAGTGAGTTGAGATTGTGCCATTGCACTCCA
  GCCTGGGCAACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_001007242
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001007242.1, NP_001007243.2
• RefSeq Size: 1998 bp
• RefSeq ORF: 1164 bp
• Locus ID: 2813
• Cytogenetics: 16p12.3
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Gene Summary: 'This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]'
  Transcript Variant: This variant (4) lacks two alternate in-frame exons in the 5' coding region compared to variant 1. The resulting protein (isoform 4, also known as beta) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.