CHMP5 (NM_016410) Human Untagged Clone

CAT#: SC324480

CHMP5 (untagged)-Human chromatin modifying protein 5 (CHMP5), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CHMP5
• Synonyms: C9orf83; CGI-34; HSPC177; PNAS-2; SNF7DC2; Vps60
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016410.2 GGGGAAGTCGAGGCGGGAGTGACTCTGCTTCCGTTTCTGGTTTTGCTCTAGTGTTTGGGT
  TTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCC
  GCCCAGCCTGACTGGCTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAA
  GATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGA
  GGGTCCTGCAAAGAATATGGTCAAGCAGAAAGCCTTGCGAGTTTTAAAGCAAAAGAGGAT
  GTATGAGCAGCAGCGGGACAATCTTGCCCAACAGTCATTCAACATGGAACAAGCCAATTA
  TACCATCCAGTCTTTGAAGGACACCAAGACCACGGTTGATGCTATGAAACTGGGAGTAAA
  GGAAATGAAGAAGGCATACAAGCAAGTGAAGATCGACCAGATTGAGGATTTACAAGACCA
  GCTAGAGGATATGATGGAAGATGCAAATGAAATCCAAGAAGCACTGAGTCGCAGTTATGG
  CACCCCAGAACTGGATGAAGATGATTTAGAAGCAGAGTTGGATGCACTAGGTGATGAGCT
  TCTGGCTGATGAAGACAGTTCTTATTTGGATGAGGCAGCATCTGCACCTGCAATTCCAGA
  AGGTGTTCCCACTGATACAAAAAACAAGGATGGAGTTCTGGTGGATGAATTTGGATTGCC
  ACAGATCCCTGCTTCATAGATTTGCATCATTCAAGCATATCTTGTAAAACAAACACATAT
  TATGGGACTAGGAAATATTTATCTTTCCAAATTTGCCATAACAGATTTAGGTTTCTTTCC
  TTTCTTTGAAGGAAAGTTTAATTACATTGCTCTTTTATTTTTTCCATTAAGAGACTCATT
  GCTTGGGAAATGCTTTCTTCGTACTAAAATTTGATTCCTTTTTTTCTTATGAAAAACGAA
  CTCAGTTTAAAAGTATTTTTAGCTCGTATGACTTGTTTTCATTCATTAATAATAATTTGA
  AATAAAACTAAGGAAATGGAATCTTAAAAGTCTATGACAGTGTAACTCTACAGTCTCAAA
  ATGACCTGATAAATTGATAAGACAAAGATGAGATTATTGGGGCTGTTCATATTATGATTC
  AGAATCATTTTCTATTGTGGTATTATAGGTTGGTTAAAGTGATGGCCTTTTTGATGGGTT
  TTGTTGTGTCTTGTGAACAAGTCGTTACTGTGTCCATTATTGGAATGGAATTATCACTAC
  TGTATCATGAGTGGGTATTTTGATTCTATGGTTCCCTCAGTATTACATCTTGACTTGTAA
  TCAATTATGAATATTTCTTGATATTTAATGTATAGGACATTTATTTATACTCAATAAATA
  TTTTTCAAAAGGAAAAAAAAAAAAATCAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016410.2 unedited
  CACGATTTGTATACGACTCCTATAGGGCGGCCGGGAATCGGCCATTACGGCCGGGGAAGT
  CGAGGCGGGAGTGACTCTGCTTCCGTTTCTGGTTTTGCTCTAGTGTTTGGGTTTCTTCGC
  GGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCC
  TGACTGGCTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTC
  GATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTG
  CAAAGAATATGGTCAAGCAGAAAGCCTTGCGAGTTTTAAAGCAAAAGAGGATGTATGAGC
  AGCAGCGGGACAATCTTGCCCAACAGTCATTCAACATGGAACAAGCCAATTATACCATCC
  AGTCTTTGAAGGACACCAAGACCACGGTTGATGCTATGAAACTGGGAGTAAAGGAAATGA
  AGAAGGCATACAAGCAAGTGAAGATCGACCAGATTGAGGATTTACAAGACCAGCTAGAGG
  ATATGATGGAAGATGCAAAATGAAATCCAAGAAGCACTGAGTCGCAGCTATGGCACCCCA
  GAACTGGATGAAAGAGGATTTATAAAACAGAGTGGGACGCACTACGTGATGAGCCGTCCG
  GGCTCGCTGCAAC
• Restriction Sites: Please inquire
• ACCN: NM_016410
• ORF Size: 660 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016410.2, NP_057494.2
• RefSeq Size: 1434
• RefSeq ORF: 660
• Locus ID: 51510
• Domains: DUF279
• Protein Pathways: Endocytosis
• Gene Summary: CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.