KEAP1 (NM_203500) Human Untagged Clone

CAT#: SC324644

KEAP1 (untagged)-Human kelch-like ECH-associated protein 1 (KEAP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KEAP1
• Synonyms: INrf2; KLHL19
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_203500.1 GAGTGCCAGAGGTGGTGGTGTTGCTTATCTTCTGGAACCCCATGCAGCCAGATCCCAGGC
  CTAGCGGGGCTGGGGCCTGCTGCCGATTCCTGCCCCTGCAGTCACAGTGCCCTGAGGGGG
  CAGGGGACGCGGTGATGTACGCCTCCACTGAGTGCAAGGCGGAGGTGACGCCCTCCCAGC
  ATGGCAACCGCACCTTCAGCTACACCCTGGAGGATCATACCAAGCAGGCCTTTGGCATCA
  TGAACGAGCTGCGGCTCAGCCAGCAGCTGTGTGACGTCACACTGCAGGTCAAGTACCAGG
  ATGCACCGGCCGCCCAGTTCATGGCCCACAAGGTGGTGCTGGCCTCATCCAGCCCTGTCT
  TCAAGGCCATGTTCACCAACGGGCTGCGGGAGCAGGGCATGGAGGTGGTGTCCATTGAGG
  GTATCCACCCCAAGGTCATGGAGCGCCTCATTGAATTCGCCTACACGGCCTCCATCTCCA
  TGGGCGAGAAGTGTGTCCTCCACGTCATGAACGGTGCTGTCATGTACCAGATCGACAGCG
  TTGTCCGTGCCTGCAGTGACTTCCTGGTGCAGCAGCTGGACCCCAGCAATGCCATCGGCA
  TCGCCAACTTCGCTGAGCAGATTGGCTGTGTGGAGTTGCACCAGCGTGCCCGGGAGTACA
  TCTACATGCATTTTGGGGAGGTGGCCAAGCAAGAGGAGTTCTTCAACCTGTCCCACTGCC
  AACTGGTGACCCTCATCAGCCGGGACGACCTGAACGTGCGCTGCGAGTCCGAGGTCTTCC
  ACGCCTGCATCAACTGGGTCAAGTACGACTGCGAACAGCGACGGTTCTACGTCCAGGCGC
  TGCTGCGGGCCGTGCGCTGCCACTCGTTGACGCCGAACTTCCTGCAGATGCAGCTGCAGA
  AGTGCGAGATCCTGCAGTCCGACTCCCGCTGCAAGGACTACCTGGTCAAGATCTTCGAGG
  AGCTCACCCTGCACAAGCCCACGCAGGTGATGCCCTGCCGGGCGCCCAAGGTGGGCCGCC
  TGATCTACACCGCGGGCGGCTACTTCCGACAGTCGCTCAGCTACCTGGAGGCTTACAACC
  CCAGTGACGGCACCTGGCTCCGGTTGGCGGACCTGCAGGTGCCGCGGAGCGGCCTGGCCG
  GCTGCGTGGTGGGCGGGCTGTTGTACGCCGTGGGCGGCAGGAACAACTCGCCCGACGGCA
  ACACCGACTCCAGCGCCCTGGACTGTTACAACCCCATGACCAATCAGTGGTCGCCCTGCG
  CCCCCATGAGCGTGCCCCGTAACCGCATCGGGGTGGGGGTCATCGATGGCCACATCTATG
  CCGTCGGCGGCTCCCACGGCTGCATCCACCACAACAGTGTGGAGAGGTATGAGCCAGAGC
  GGGATGAGTGGCACTTGGTGGCCCCAATGCTGACACGAAGGATCGGGGTGGGCGTGGCTG
  TCCTCAATCGTCTCCTTTATGCCGTGGGGGGCTTTGACGGGACAAACCGCCTTAATTCAG
  CTGAGTGTTACTACCCAGAGAGGAACGAGTGGCGAATGATCACAGCAATGAACACCATCC
  GAAGCGGGGCAGGCGTCTGCGTCCTGCACAACTGTATCTATGCTGCTGGGGGCTATGATG
  GTCAGGACCAGCTGAACAGCGTGGAGCGCTACGATGTGGAAACAGAGACGTGGACTTTCG
  TAGCCCCCATGAAGCACCGGCGAAGTGCCCTGGGGATCACTGTCCACCAGGGGAGAATCT
  ACGTCCTTGGAGGCTATGATGGTCACACGTTCCTGGACAGTGTGGAGTGTTACGACCCAG
  ATACAGACACCTGGAGCGAGGTGACCCGAATGACATCGGGCCGGAGTGGGGTGGGCGTGG
  CTGTCACCATGGAGCCCTGCCGGAAGCAGATTGACCAGCAGAACTGTACCTGTTGAGGCA
  CTTTTGTTTCTTGGGCAAAAATACAGTCCAATGGGGAGTATCATTGTTTTTGTACAAAAA
  CCGGGACTAAAAGAAAAGACAGCACTGCAAATAACCCATCTTCCGGGAAGGGAGGCCAGG
  ATGCCTCAGTGTTAAAATGACATCTCAAAAGAAGTCCAAAGCGGGAATCATGTGCCCCTC
  AGCGGAGCCCCGGGAGTGTCCAAGACAGCCTGGCTGGGAAAGGGGGTGTGGAAAGAGCAG
  GCTTCCAGGAGAGAGGCCCCCAAACCCTCTGGCCGGGTAATAGGCCTGGGTCCCACTCAC
  CCATGCCGGCAGCTGTCACCATGTGATTTATTCTTGGATACCTGGGAGGGGGCCAATGGG
  GGCCTCAGGGGGAGGCCCCCTCTGGAAATGTGGTTCCCAGGGATGGGCCTGTACATAGAA
  GCCACCGGATGGCACTTCCCCACCGGATGGACAGTTATTTTGTTGATAAGTAACCCTGTA
  ATTTTCCAAGGAAAATAAAGAACAGACTAACTAGTGTCTTTCACCCTGAAAAAAAAAAAA
  AA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_203500.1 unedited
  GTAACCATATGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGT
  CCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGGAGTGCCAGAGGTGGTGGTGTTGC
  TTATCTTCTGGAACCCCATGCAGCCAGATCCCAGGCCTAGCGGGGCTGGGGCCTGCTGCC
  GATTCCTGCCCCTGCAGTCACAGTGCCCTGAGGGGGCAGGGGACGCGGTGATGTACGCCT
  CCACTGAGTGCAAGGCGGAGGTGACGCCCTCCCAGCATGGCAACCGCACCTTCAGCTACA
  CCCTGGAGGATCATACCAAGCAGGCCTTTGGCATCATGAACGAGCTGCGGCTCAGCCAGC
  AGCTGTGTGACGTCACACTGCAGGTCAAGTACCAGGATGCACCGGCCGCCCAGTTCATGG
  CCCACAAGGTGGTGCTGGCCTCATCCAGCCCTGTCTTCAAGGCCATGTTCACCAACGGGC
  TGCGGGAGCAGGGCATGGAGGTGGTGTCCATTGAGGGTATCCACCCCAAGGTCATGGAGC
  GCCTCATTGAATTCGCCTACACGGCCTCCATCTCCATGGGCGAGAAGTGTGTCCTCCACG
  TCATGAACGGTGCTGTCATGTACCAGATCGACAGCGTTGTCCGTGCCCTGCAGTGACTTC
  CTGGTGCAGCAGCTGGACCCCAGCAATGCCATCGGCATCGCCAACTTCGCTGAGCAGATT
  GCCTGTGTGGAGGTTGCACCAGCGTGCCCCGGAGTACATCTAACATGCATTTTTGGGGAG
  GTGGCCCAAGCAGGATGGAGTTCTTCAACCCTGTCCCACTGCCAACTTGGTGACCCTCAT
  CAGCCGGAACGACTTGAACGTGCGCTGCGAAGTCGGAGTTCTTCACGTCTTGCATCAACT
  GGGTCCAAGTTACGAACTGCAAATAAGCGACGGTTTCTATCATTC
• Restriction Sites: Please inquire
• ACCN: NM_203500
• ORF Size: 1875 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_203500.1, NP_987096.1
• RefSeq Size: 2606
• RefSeq ORF: 1875
• Locus ID: 9817
• Protein Families: Transcription Factors
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript.