AMIGO2 (NM_001143668) Human Untagged Clone

CAT#: SC325158

AMIGO2 (untagged)-Human adhesion molecule with Ig-like domain 2 (AMIGO2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AMIGO2
• Synonyms: ALI1; AMIGO-2; DEGA
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001143668, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCGTTACGTGTACACACTCTGCCCACCCTGCTTGGAGCCGTCGTCAGACCGGGCTGCAGGGAGCTGC
  TGTGTTTGCTGATGATCACAGTGACTGTGGGCCCTGGTGCCTCTGGGGTGTGCCCCACCGCTTGCATCTG
  TGCCACTGACATCGTCAGCTGCACCAACAAAAACCTGTCCAAGGTGCCTGGGAACCTTTTCAGACTGATT
  AAGAGACTGGACCTGAGTTATAACAGAATTGGGCTTCTGGATTCTGAGTGGATTCCAGTATCGTTTGCAA
  AGCTGAACACCCTAATTCTTCGTCATAACAACATCACCAGCATTTCCACGGGCAGTTTTTCCACAACTCC
  AAATTTGAAGTGTCTTGACTTATCGTCCAATAAGCTGAAGACGGTGAAAAATGCTGTATTCCAAGAGTTG
  AAGGTTCTGGAAGTGCTTCTGCTTTACAACAATCACATATCCTATCTCGATCCTTCAGCGTTTGGAGGGC
  TCTCCCAGTTGCAGAAACTCTACTTAAGTGGAAATTTTCTCACACAGTTTCCGATGGATTTGTATGTTGG
  AAGGTTCAAGCTGGCAGAACTGATGTTTTTAGATGTTTCTTATAACCGAATTCCTTCCATGCCAATGCAC
  CACATAAATTTAGTGCCAGGAAAACAGCTGAGAGGCATCTACCTTCATGGAAACCCATTTGTCTGTGACT
  GTTCCCTGTACTCCTTGCTGGTCTTTTGGTATCGTAGGCACTTTAGCTCAGTGATGGATTTTAAGAACGA
  TTACACCTGTCGCCTGTGGTCTGACTCCAGGCACTCGCGTCAGGTACTTCTGCTCCAGGATAGCTTTATG
  AATTGCTCTGACAGCATCATCAATGGTTCCTTTCGTGCGCTTGGCTTTATTCATGAGGCTCAGGTCGGGG
  AAAGACTGATGGTCCACTGTGACAGCAAGACAGGTAATGCAAATACGGATTTCATCTGGGTGGGTCCAGA
  TAACAGACTGCTAGAGCCGGATAAAGAGATGGAAAACTTTTACGTGTTTCACAATGGAAGTCTGGTTATA
  GAAAGCCCTCGTTTTGAGGATGCTGGAGTGTATTCTTGTATCGCAATGAATAAGCAACGCCTGTTAAATG
  AAACTGTGGACGTCACAATAAATGTGAGCAATTTCACTGTAAGCAGATCCCATGCTCATGAGGCATTTAA
  CACAGCTTTTACCACTCTTGCTGCTTGCGTGGCCAGTATCGTTTTGGTACTTTTGTACCTCTATCTGACT
  CCATGCCCCTGCAAGTGTAAAACCAAGAGACAGAAAAATATGCTACACCAAAGCAATGCCCATTCATCGA
  TTCTCAGTCCTGGCCCCGCTAGTGATGCCTCCGCTGATGAACGGAAGGCAGGTGCAGGTAAAAGAGTGGT
  GTTTTTGGAACCCCTGAAGGATACTGCAGCAGGGCAGAACGGGAAAGTCAGGCTCTTTCCCAGCGAGGCA
  GTGATAGCTGAGGGCATCCTAAAGTCCACGAGGGGGAAATCTGACTCAGATTCAGTCAATTCAGTGTTTT
  CTGACACACCTTTTGTGGCGTCCACTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001143668
• ORF Size: 1569 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001143668.1, NP_001137140.1
• RefSeq Size: 3126
• RefSeq ORF: 1569
• Locus ID: 347902
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) includes an alternate exon in the 5' UTR. The same protein is encoded by transcript variants 1-3.