PTPH1 (PTPN3) (NM_001145371) Human Untagged Clone

CAT#: SC325244

PTPN3 (untagged)-Human protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPN3
• Synonyms: PTP-H1; PTPH1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001145371, the custom clone sequence may differ by one or more nucleotides
  ATGCTGAATTACCGATCTTGCAAAAACTTGTGGAAATCCTGTGTTGAGCACCATACGTTC
  TTTCAGGCAAAGAAGCTACTACCTCAGGAAAAGAATGTTCTGTCTCAGTACTGGACTATG
  GGCTCTCGGAACACCAAAAAGTCGGTAAATAACCAATATTGCAAAAAGGTGATTGGCGGG
  ATGGTGTGGAACCCAGCCATGCGGAGATCCTTATCAGTGGAGCACTTAGAAACCAAGAGT
  CTGCCTTCTCGTTCCCCTCCCATTACTCCCAACTGGCGAAGTCCTCGGCTCCGGCACGAA
  ATCCGAAAGCCACGCCACTCTTCTGCAGATAACCTTGCAAATGAAATGACCTACATCACG
  GAAACGGAAGATGTATTTTACACGTACAAGGGCTCTCTGGCCCCTCAAGACAGCGATTCT
  GAAGTTTCTCAGAACCGAAGCCCGCACCAAGAGAGTTTATCCGAGAACAATCCGGCACAA
  AGCTACCTGACCCAGAAGTCATCCAGTTCTGTGTCTCCATCTTCAAATGCTCCAGGCTCC
  TGCTCACCTGACGGCGTTGATCAGCAGCTCTTAGATGACTTCCACAGGGTGACCAAAGGG
  GGCTCCACCGAGGACGCCAGCCAGTACTACTGTGACAAGAATGATAATGGTGACAGCTAC
  TTAGTCTTGATCCGTATCACACCAGATGAAGATGGAAAATTTGGATTTAATCTTAAGGGA
  GGAGTGGATCAAAAGATGCCTCTTGTGGTATCAAGGATAAACCCAGAGTCACCTGCGGAC
  ACCTGCATTCCTAAGCTGAACGAAGGGGATCAAATCGTGTTAATCAATGGCCGGGACATC
  TCAGAACACACGCATGACCAAGTGGTGATGTTCATCAAAGCCAGCCGGGAGTCCCACTCA
  CGGGAGCTGGCCCTGGTGATCAGGAGGAGAGCTGTCCGCTCATTTGCTGACTTCAAGTCT
  GAAGATGAACTGAACCAGCTTTTCCCCGAAGCCATTTTCCCCATGTGTCCGGAGGGTGGG
  GACACTTTGGAGGGATCCATGGCACAGCTAAAGAAGGGCCTCGAAAGCGGGACGGTGCTG
  ATCCAGTTTGAGCAACTCTACAGAAAAAAGCCAGGTTTGGCCATCACGTTTGCAAAGCTG
  CCTCAAAATTTGGACAAAAACCGATATAAAGATGTGCTGCCTTATGACACCACCCGGGTA
  TTATTGCAGGGAAATGAAGATTATATTAATGCAAGTTACGTGAACATGGAAATTCCTGCT
  GCTAACCTTGTGAACAAGTACATCGCCACTCAGGGGCCCCTGCCGCATACCTGTGCACAG
  TTTTGGCAGGTTGTCTGGGATCAGAAGTTGTCACTCATTGTCATGTTGACGACTCTCACA
  GAACGAGGGCGGACCAAATGTCACCAGTACTGGCCAGATCCCCCCGACGTCATGAACCAC
  GGCGGCTTTCACATCCAGTGTCAGTCAGAGGACTGCACCATCGCCTATGTGTCCCGAGAA
  ATGCTGGTCACAAACACCCAGACCGGGGAAGAACACACAGTGACACATCTCCAGTACGTC
  GCATGGCCTGACCACGGTGTGCCCGATGACTCCTCCGACTTTCTGGAATTTGTAAACTAT
  GTGAGGTCTCTGAGAGTGGACAGCGAGCCCGTCCTAGTTCACTGCAGTGCTGGAATAGGT
  CGAACCGGTGTGTTGGTCACTATGGAAACAGCCATGTGCCTAACTGAGAGGAACCTGCCC
  ATTTACCCACTGGATATTGTCCGAAAAATGCGAGACCAGCGCGCCATGATGGTGCAGACA
  TCAAGCCAGTACAAGTTTGTGTGTGAAGCGATTCTTCGTGTGTATGAAGAAGGTTTAGTC
  CAAATGCTGGATCCTAGT
  
• Restriction Sites: Please inquire
• ACCN: NM_001145371
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001145371.1, NP_001138843.1
• RefSeq Size: 6217 bp
• RefSeq ORF: 1881 bp
• Locus ID: 5774
• Cytogenetics: 9q31.3
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]'
  Transcript Variant: This variant (5) differs in the 5' UTR, and initiates translation from an in-frame downstream AUG, resulting in an isoform (5) with a shorter N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.