KLC2 (NM_001134774) Human Untagged Clone

CAT#: SC326058

KLC2 (untagged)-Human kinesin light chain 2 (KLC2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KLC2
• Synonyms: SPOAN
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001134774, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCATGATGGTGTTTCCGCGGGAGGAGAAGCTGAGCCAGGATGAGATCGTGCTGGGCACCAAGGCTG
  TCATCCAGGGACTGGAGACTCTGCGTGGGGAGCATCGTGCCCTGCTGGCTCCTCTGGTTGCACCTGAGGC
  CGGCGAAGCCGAGCCTGGCTCGCAGGAGCGCTGCATCCTCCTGCGTCGCTCCCTGGAAGCCATTGAGCTT
  GGGCTGGGGGAGGCCCAGGAGGAGAAGGGGGACGTCCCCAAAGACACACTGGATGACCTGTTCCCCAATG
  AGGATGAGCAGAGCCCAGCCCCTAGCCCAGGAGGAGGGGATGTGTCTGGTCAGCATGGGGGCTACGAGAT
  CCCGGCCCGGCTCCGCACCCTGCACAACCTGGTGATCCAATACGCCTCACAGGGCCGCTACGAGGTAGCT
  GTGCCACTCTGCAAGCAGGCACTCGAAGACCTGGAGAAGACGTCAGGCCACGACCACCCTGACGTTGCCA
  CCATGCTGAACATCCTGGCACTGGTCTATCGGGATCAGAACAAGTACAAGGAGGCTGCCCACCTGCTCAA
  TGATGCTCTGGCCATCCGGGAGAAAACACTGGGCAAGGACCACCCAGCCGTGGCTGCGACACTAAACAAC
  CTGGCAGTCCTGTATGGCAAGAGGGGCAAGTACAAGGAGGCTGAGCCATTGTGCAAGCGGGCACTGGAGA
  TCCGGGAGAAGGTCCTGGGCAAGTTTCACCCAGATGTGGCCAAGCAGCTCAGCAACCTGGCCCTGCTGTG
  CCAGAACCAGGGCAAAGCTGAGGAGGTGGAATATTACTATCGGCGGGCACTGGAGATCTATGCTACACGC
  CTCGGGCCCGATGACCCCAATGTGGCCAAGACCAAGAACAACCTGGCTTCCTGCTACCTGAAGCAGGGCA
  AGTACCAGGATGCGGAGACCTTGTACAAGGAGATCCTCACCCGCGCTCATGAGAAAGAGTTTGGCTCTGT
  CAATGGGGACAACAAGCCCATCTGGATGCACGCAGAGGAGCGGGAGGAAAGCAAGGATAAGCGCCGGGAC
  AGCGCCCCCTATGGGGAATACGGCAGCTGGTACAAGGCCTGTAAAGTAGACAGCCCCACAGTCAACACCA
  CCCTGCGCAGCTTGGGGGCCCTATACCGGCGCCAGGGCAAGCTGGAAGCCGCGCACACACTAGAGGACTG
  TGCCAGCCGTAACCGCAAGCAGGGTTTGGACCCCGCAAGCCAGACCAAGGTGGTAGAACTGCTGAAAGAT
  GGCAGTGGCAGGCGGGGAGACCGCCGCAGCAGCCGAGACATGGCTGGGGGTGCCGGGCCTCGGTCTGAGT
  CTGACCTCGAGGACGTGGGACCTACAGCTGAGTGGAATGGGGATGGCAGTGGCTCCTTGAGGCGCAGCGG
  TTCCTTTGGGAAACTCCGGGATGCCCTGAGGCGCAGCAGTGAGATGCTGGTAAAGAAGCTGCAGGGGGGC
  ACCCCCCAGGAGCCCCCTAACCCCAGGATGAAGCGGGCCAGTTCCCTCAACTTCCTCAACAAGAGCGTGG
  AAGAGCCGACCCAGCCTGGAGGCACAGGTCTCTCTGACAGCCGCACTCTCAGCTCCAGCTCCATGGACCT
  CTCCCGACGAAGCTCCCTGGTGGGCTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001134774
• ORF Size: 1638 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001134774.1, NP_001128246.1
• RefSeq Size: 2733
• RefSeq ORF: 1638
• Locus ID: 64837
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a light chain of kinesin, a molecular motor responsible for moving vesicles and organelles along microtubules. Defects in this gene are a cause of spastic paraplegia, optic atrophy, and neuropathy (SPOAN) syndrome. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (2) omits an in-frame coding exon resulting in a shorter protein isoform (2) compared to variant 1. It also reflects use of an alternate splice acceptor site in exon 2.