RIOK2 (NM_001159749) Human Untagged Clone

CAT#: SC327028

RIOK2 (untagged)-Human RIO kinase 2 (yeast) (RIOK2) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RIOK2
• Synonyms: RIO2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001159749, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGAAAGTGAATGTGGCCAAGTTGCGTTACATGAGCCGAGATGACTTCAGGGTCTTGACCGCGGTTG
  AAATGGGCATGAAGAACCATGAAATTGTTCCCGGCAGTTTGATTGCTTCTATAGCCAGCCTTAAACATGG
  TGGCTGTAATAAAGTTTTAAGAGAATTAGTGAAACATAAACTCATAGCTTGGGAGCGTACCAAAACTGTC
  CAGGGCTATCGGTTGACAAATGCAGGATATGATTACCTAGCTTTGAAAACACTTTCTTCTAGGCAAGTAG
  TTGAGTCTGTTGGAAACCAGATGGGTGTTGGCAAAGAATCAGATATTTACATTGTTGCAAATGAAGAAGG
  ACAACAATTTGCATTAAAGCTTCACAGACTAGGAAGAACCTCGTTTCGAAATTTGAAAAACAAACGCGAT
  TATCATAAACATAGGCACAATGTGTCATGGCTATATTTATCTCGTCTCTCTGCCATGAAGGAATTTGCCT
  ATATGAAGGCATTGTATGAGAGGAAATTTCCAGTTCCAAAGCCAATTGATTACAATCGTCATGCAGTGGT
  CATGGAACTCATAAATGGTTATCCACTATGTCAGATACACCATGTTGAAGATCCTGCATCAGTATATGAT
  GAAGCTATGGAACTAATTGTCAAACTTGCAAATCATGGGCTGATTCATGGAGATTTTAATGAATTTAATC
  TCATTTTGGATGAAAGTGACCATATCACCATGATTGATTTTCCACAGATGGTTTCAACTTCTCATCCCAA
  TGCTGAGTGGTATTTTGACAGAGATGTTAAATGCATTAAAGATTTCTTTATGAAACGTTTCAGCTACGAA
  AGTGAGCTTTTTCCAACTTTTAAGGATATCAGGAGAGAAGACACTCTTGATGTGGAGGTTTCTGCCAGTG
  GCTACACAAAGGAAATGCAGGCAGATGATGAACTGCTTCATCCATTAGGTCCAGATGATAAAAATATTGA
  AACAAAAGAGGGATCTGAATTCTCATTTTCAGATGGAGAAGTGGCAGAAAAAGCAGAGGTTTACGGGTCA
  GAAAATGAAAGTGAACGGAACTGTCTAGAAGAATCAGAGGGCTGCTATTGCAGATCATCTGGAGACCCTG
  AACAAATAAAGGAAGACAGTTTATCAGAAGAGAGTGCTGATGCACGGAGTTTTGAAATGACTGAATTCAA
  TCAAGCTTTAGAAGAAATAAAAGGGCAGGTTGTTGAAAACAACTCTGTAACTGAATTTTCTGAGGAGAAA
  AACAGAACTGAAAATTACAACAGGCAAGATGGTCAGAGAGTTCAAGGAGGAGTCCCTGCTGGCTCTGACG
  AGTATGAAGATGAATGCCCTCATCTAATTGCCTTGTCGTCATTAAATAGAGAATTCAGGCCTTTCAGGTA
  TAGACTTCTGTCGATTGCTTTTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001159749
• ORF Size: 1425 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001159749.1, NP_001153221.1
• RefSeq Size: 2240
• RefSeq ORF: 1425
• Locus ID: 55781
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its catalytic activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.