ADAM8 (NM_001164490) Human Untagged Clone

CAT#: SC327198

ADAM8 (untagged)-Human ADAM metallopeptidase domain 8 (ADAM8) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADAM8
• Synonyms: CD156; CD156a; MS2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001164490, the custom clone sequence may differ by one or more nucleotides
  ATGCGCGGCCTCGGGCTCTGGCTGCTGGGCGCGATGATGCTGCCTGGGCCTGCACCCAGA
  GAGGGTGAGCTACGTCCTTGGGGCCACAGGGCACAACTTCACCCTCCACCTGCGGAAGAA
  CAGGGACCTGCTGGGCTCCGGCTACACAGAGACCTATACGGCTGCCAATGGCTCCGAGGT
  GACGGAGCAGCCTCGCGGGCAGGACCACTGCTTCTACCAGGGCCACGTAGAGGGGTACCC
  GGACTCAGCCGCCAGCCTCAGCACCTGTGCCGGCCTCAGGTGGGGTCAGACCTGCACCTG
  ATCGAGCCCCTGGATGAAGGTGGCGAGGGCGGACGGCACGCCGTGTACCAGGCTGAGCAC
  CTGCTGCAGACGGCCGGGACCTGCGGGGTCAGCGACGACAGCCTGGGCAGCCTCCTGGGA
  CCCCGGACGGCAGCCGTCTTCAGGCCTCGGCCCGGGGACTCTCTGCCATCCCGAGAGACC
  CGCTACGTGGAGCTGTATGTGGTCGTGGACAATGCAGAGTTCCAGATGCTGGGGAGCGAA
  GCAGCCGTGCGTCATCGGGTGCTGGAGGTGGTGAATCACGTGGACAAGCTATATCAGAAA
  CTCAACTTCCGTGTGGTCCTGGTGGGCCTGGAGATTTGGAATAGTCAGGACAGGTTCCAC
  GTCAGCCCCGACCCCAGTGTCACACTGGAGAACCTCCTGACCTGGCAGGCACGGCAACGG
  ACACGGCGGCACCTGCATGACAACGTACAGCTCATCACGGGTGTCGACTTCACCGGGACT
  ACCGTGGGGTTTGCCAGGGTGTCCGCCATGTGCTCCCACAGCTCAGGGGCTGTGAACCAG
  GACCACAGCAAGAACCCCGTGGGCGTGGCCTGTACCATGGCCCATGAGATGGGCCACAAC
  CTGGGCATGGACCATGATGAGAACGTCCAGGGCTGCCGCTGCCAGGAACGCTTCGAGGCC
  GGCCGCTGCATCATGGCGGGCAGCATTGGCTCCAGTTTCCCCAGGATGTTCAGTGACTGC
  AGCCAGGCCTACCTGGAGAGCTTTTTGGAGCGGCCGCAGTCGGTGTGCCTCGCCAACGCC
  CCTGACCTCAGCCACCTGGTGGGCGGCCCCGTGTGTGGGAACCTGTTTGTGGAGCGTGGG
  GAGCAGTGCGACTGCGGCCCCCCCGAGGACTGCCGGAACCGCTGCTGCAACTCTACCACC
  TGCCAGCTGGCTGAGGGGGCCCAGTGTGCGCACGGTACCTGCTGCCAGGAGTGCAAGGTG
  AAGCCGGCTGGTGAGCTGTGCCGTCCCAAGAAGGACATGTGTGACCTCGAGGAGTTCTGT
  GACGGCCGGCACCCTGAGTGCCCGGAAGACGCCTTCCAGGAGAACGGCACGCCCTGCTCC
  GGGGGCTACTGCTACAACGGGGCCTGTCCCACACTGGCCCAGCAGTGCCAGGCCTTCTGG
  GGGCCAGGTGGGCAGGCTGCCGAGGAGTCCTGCTTCTCCTATGACATCCTACCAGGCTGC
  AAGGCCAGCCGGTACAGGGCTGACATGTGTGGCGTTCTGCAGTGCAAGGGTGGGCAGCAG
  CCCCTGGGGCGTGCCATCTGCATCGTGGATGTGTGCCACGCGCTCACCACAGAGGATGGC
  ACTGCGTATGAACCAGTGCCCGAGGGCACCCGGTGTGGACCAGAGAAGGTGTGCAACCAC
  AAGCAGGAGTGCCACTGCCACGCGGGCTGGGCCCCGCCCCACTGCGCGAAGCTGCTGACT
  GAGGTGCACGCAGCGTCCGGGAGCCTCCCCGTCTTCGTGGTGGTGGTTCTGGTGCTCCTG
  GCAGTTGTGCTGGTCACCCTGGCAGGCATCATCGTCTACCGCAAAGCCCGGAGCCGCATC
  CTGAGCAGGAACGTGGCTCCCAAGACCACAATGGGGCGCTCCAACCCCCTGTTCCACCAG
  GCTGCCAGCCGCGTGCCGGCCAAGGGCGGGGCTCCAGCCCCATCCAGGGGCCCCCAAGAG
  CTGGTCCCCACCACCCACCCGGGCCAGCCCGCCCGACACCCGGCCTCCTCGGTGGCTCTG
  AAGAGGCCGCCCCCTGCTCCTCCGGTCACTGTGTCCAGCCCACCCTTCCCAGTTCCTGTC
  TACACCCGGCAGGCACCAAAGCAGGGTGCTGTTGGCCCAAAGGTTGCCCTGAAGCCCCCC
  ATCCAGAGGAAGCAAGGAGCCGGAGCTCCCACAGCACCC
  
• Restriction Sites: Please inquire
• ACCN: NM_001164490
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001164490.1, NP_001157962.1
• RefSeq Size: 3043 bp
• RefSeq ORF: 2202 bp
• Locus ID: 101
• Cytogenetics: 10q26.3
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: 'This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]'
  Transcript Variant: This variant (3) lacks three alternate exons and uses an alternate splice site in the coding region, which results in a frameshifted segment, compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter than isoform 1.