KDM4C (NM_001146696) Human Untagged Clone

CAT#: SC327228

KDM4C (untagged)-Human lysine (K)-specific demethylase 4C (KDM4C) transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KDM4C
• Synonyms: GASC1; JHDM3C; JMJD2C; TDRD14C
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001146696, the custom clone sequence may differ by one or more nucleotides
  ATGAAGCACTATGGGCTGCCCTGGAAGAGGACTGAAGAAGCAGCTGCAGACACTGCCCTA
  ACCATCATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCAGCTGTAAGATAATGACC
  TTCAGACCCTCCATGGAGGAGTTCCGGGAGTTCAACAAATACCTTGCATACATGGAGTCT
  AAAGGAGCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCCTAAGGAGTGGAAGCCAAGA
  CAGTGCTATGATGACATTGATAATTTGCTCATTCCAGCACCAATTCAGCAGATGGTCACA
  GGGCAGTCAGGACTGTTCACTCAGTACAACATCCAGAAAAAAGCGATGACTGTGAAGGAG
  TTCAGGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAGATACTTGGATTACGAAGAT
  TTGGAGCGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTATCTATGGTGCAGATATT
  AATGGGAGCATATATGATGAGGGTGTGGATGAATGGAACATAGCTCGCCTCAATACAGTC
  TTGGATGTGGTTGAAGAAGAGTGTGGCATTTCTATTGAGGGTGTAAATACCCCATATCTC
  TATTTTGGCATGTGGAAGACCACGTTTGCATGGCACACCGAAGACATGGACCTCTATAGC
  ATTAATTATCTCCACTTTGGAGAGCCCAAGTCTTGGTATGCTATACCTCCGGAGCATGGA
  AAACGACTTGAAAGACTAGCTCAAGGTTTTTTCCCAAGCAGCTCCCAAGGGTGTGATGCA
  TTTCTTCGCCACAAGATGACATTGATTTCTCCATCAGTATTGAAGAAATATGGTATTCCC
  TTTGACAAGATAACCCAGGAGGCTGGAGAATTCATGATCACTTTCCCATATGGCTACCAT
  GCTGGTTTTAATCATGGTTTCAACTGTGCAGAATCTACAAATTTTGCTACTGTCAGATGG
  ATTGACTATGGAAAAGTTGCCAAATTGTGCACTTGCAGGAAAGACATGGTGAAGATTTCA
  ATGGATATCTTTGTGAGGAAATTTCAGCCAGACAGATATCAGCTTTGGAAACAAGGAAAG
  GATATATACACCATTGATCACACGAAGCCTACTCCAGCATCCACCCCTGAAGTAAAAGCA
  TGGCTGCAGAGGAGGAGGAAAGTAAGAAAAGCATCCCGAAGCTTCCAGTGTGCTAGGTCT
  ACCTCTAAAAGGCCTAAGGCTGATGAGGAAGAGGAAGTGTCAGATGAAGTCGATGGGGCA
  GAGGTCCCTAACCCCGACTCAGTCACAGATGACCTCAAGGTCAGTGAAAAGTCAGAAGCA
  GCAGTGAAGCTGAGGAACACAGAAGCATCTTCAGAAGAAGAGTCATCTGCTAGCAGGATG
  CAGGTGGAGCAGAATTTATCAGATCATATCAAACTCTCAGGAAACAGCTGCTTAAGTACA
  TCTGTAACAGAAGACATAAAAACTGAGGATGACAAAGCTTATGCATATAGAAGTGTACCT
  TCTATATCCAGTGAGGCTGATGATTCCATTCCATTGTCTAGTGGCTATGAGAAGCCCGAG
  AAATCAGACCCATCCGAGCTTTCATGGCCAAAGTCACCTGAGTCATGCTCATCAGTGGCA
  GAGAGTAATGGTGTGTTAACAGAGGGAGAAGAGAGTGATGTGGAGAGCCATGGGAATGGC
  CTTGAACCTGGGGAAATCCCAGCGGTCCCCAGTGGAGAGAGAAATAGCTTCAAAGTCCCC
  AGTATAGCAGAGGGAGAGAACAAAACCTCTAAGAGTTGGCGCCATCCACTTAGCAGGCCT
  CCAGCAAGATCTCCGATGACTCTTGTGAAGCAGCAGGCGCCAAGTGATGAAGAATTGCCT
  GAGGTTCTGTCCATTGAGGAGGAAGTGGAAGAAACAGAGTCTTGGGCGAAACCTCTCATC
  CACCTTTGGCAGACGAAGTCCCCTAACTTCGCAGCTGAGCAAGAGTATAATGCAACAGTG
  GCCAGGATGAAGCCACACTGTGCCATCTGCACTCTGCTCATGCCGTACCACAAGCCAGAT
  AGCAGCAATGAAGAAAATGATGCTAGATGGGAGACAAAATTAGATGAAGTCGTTACATCG
  GAGGGAAAGACTAAGCCCCTCATACCAGAGATGTGTTTTATTTATAGTGAAGAAAATATA
  GAATATTCTCCACCCAATGCCTTCCTTGAAGAGGATGGAACAAGTCTCCTTATTTCCTGT
  GCAAAGTGCTGCGTACGGGTTCATGCAAGTTGTTATGGTATTCCTTCTCATGAGATCTGT
  GATGGATGGCTGTGTGCCCGGTGCAAAAGAAATGCGTGGACAGCAGAATGCTGTCTCTGC
  AATTTGAGAGGAGGTGCTCTTAAGCAAACGAAGAACAATAAGTGGGCCCATGTCATGTGC
  GCCGTTGCGGTCCCAGAAGTTCGATTCACTAATGTCCCAGAAAGGACACAAATAGATGTA
  GGCAGAATACCTTTACAGAGGTTAAAATTGGGAAGGCTGGGAATC
  
• Restriction Sites: Please inquire
• ACCN: NM_001146696
• ORF Size: 2508 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001146696.1, NP_001140168.1
• RefSeq Size: 3422
• RefSeq ORF: 2508
• Locus ID: 23081
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  Transcript Variant: This variant (4) contains multiple differences in the 5' and 3' regions compared to variant 1, including initiation of translation at an alternate start codon. The resulting protein (isoform 4) has a longer N-terminus, a distinct C-terminus, and is shorte