HSPC302 (TBCK) (NM_001163435) Human Untagged Clone

CAT#: SC327245

TBCK (untagged)-Human TBC1 domain containing kinase (TBCK) transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TBCK
• Synonyms: HSPC302; IHPRF3; TBCKL
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001163435, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTTCCCCTGAAGGACGCTGAAATGGGAGCCTTTACCTTCTTTGCCTCGGCTCTGCCACATGATGTTT
  GTGGAAGCAATGGACTTCCTCTCACACCAAATTCCATCAAAATTTTAGGGCGCTTTCAAATCCTTAAAAC
  CATCACCCATCCCAGACTCTGCCAGTATGTGGATATTTCTAGGGGAAAGCATGAACGACTAGTGGTCGTG
  GCTGAACATTGTGAACGTAGTCTGGAAGACTTGCTTCGAGAAAGGAAACCTGTGAGCTGTTCAACGGTTT
  TGTGTATAGCATTTGAGGTTCTTCAGGGCTTGCAGTATATGAACAAACATGGTATAGTACACAGGGCATT
  GTCTCCTCATAATATCCTGTTGGACCGAAAGGGACATATTAAATTGGCTAAATTTGGACTTTATCACATG
  ACAGCTCATGGTGATGATGTTGATTTCCCAATAGGGTATCCCTCGTACTTGGCCCCTGAGGTAATTGCAC
  AGGGAATTTTCAAAACCACTGATCACATGCCAAGTAAAAAACCATTGCCTTCTGGCCCCAAATCAGATGT
  ATGGTCTCTTGGAATCATTTTATTTGAGCTTTGTGTGGGAAGAAAATTATTTCAGAGCTTGGATATTTCT
  GAAAGACTAAAATTTTTGCTTACTTTGGATTGTGTAGATGACACTTTAATAGTTCTGGCTGAAGAGCATG
  GTTGTTTGGACATTATAAAGGAGCTTCCTGAAACTGTGATAGATCTTTTGAATAAGTGCCTTACCTTCCA
  TCCTTCTAAGAGGCCAACCCCAGATGAATTAATGAAGGACAAAGTATTCAGTGAGGTATCACCTTTATAT
  ACCCCCTTTACCAAACCTGCCAGTCTGTTTTCATCTTCTCTGAGATGTGCTGATTTAACTCTGCCTGAGG
  ATATCAGTCAGTTGTGTAAAGATATAAATAATGATTACCTGGCAGAAAGATCTATTGAAGAAGTGTATTA
  CCTTTGGTGTTTGGCTGGAGGTGACTTGGAGAAAGAGCTTGTCAACAAGGAAATCATTCGATCCAAACCA
  CCTATCTGCACACTCCCCAATTTTCTCTTTGAGGATGGTGAAAGCTTTGGACAAGGTCGAGATAGAAGCT
  CGCTTTTAGATGATACCACTGTGACATTGTCGTTATGCCAGCTAAGAAATAGATTGAAAGATGTTGGTGG
  AGAAGCATTTTACCCATTACTTGAAGATGACCAGTCTAATTTACCTCATTCAAACAGCAATAATGAGTTG
  TCTGCAGCTGCCACGCTCCCTTTAATCATCAGAGAGAAGGATACAGAGTACCAACTAAATAGAATTATTC
  TCTTCGACAGGCTGCTAAAGGCTTATCCATATAAAAAAAACCAAATCTGGAAAGAAGCAAGAGTTGACAT
  TCCTCCTCTTATGAGAGGTTTAACCTGGGCTGCTCTTCTGGGAGTTGAGGGAGCTATTCATGCCAAGTAC
  GATGCAATTGATAAAGACACTCCAATTCCTACAGATAGACAAATTGAAGTGGATATTCCTCGCTGTCATC
  AGTACGATGAACTGTTATCATCACCAGAAGGTCATGCAAAATTTAGGCGTGTATTAAAAGCCTGGGTAGT
  GTCTCATCCTGATCTTGTGTATTGGCAAGGTCTTGACTCACTTTGTGCTCCATTCCTATATCTAAACTTC
  AATAATGAAGCCTTGGCTTATGCATGTATGTCTGCTTTTATTCCCAAATACCTGTATAACTTCTTCTTAA
  AAGACAACTCACATGTAATACAAGAGTATCTGACTGTCTTCTCTCAGATGATTGCATTTCATGATCCAGA
  GCTGAGTAATCATCTCAATGAGATTGGTTTCATTCCAGATCTCTATGCCATCCCTTGGTTTCTTACCATG
  TTTACTCATGTATTTCCACTACACAAAATTTTCCACCTCTGGGATACCTTACTACTTGGGAATTCCTCTT
  TCCCATTCTGTATTGGAGTAGCAATTCTTCAGCAGCTGCGGGACCGGCTTTTGGCTAATGGCTTTAATGA
  GTGTATTCTTCTCTTCTCCGATTTACCAGAAATTGACATTGAACGCTGTGTGAGAGAATCTATCAACCTG
  TTTTGTTGGACTCCTAAAAGTGCTACTTACAGACAGCATGCTCAACCTCCAAAGCCATCTTCTGACAGCA
  GTGGAGGCAGAAGTTCGGCACCTTATTTCTCTGCTGAGTGTCCAGATCCTCCAAAGACAGATCTGTCAAG
  AGAATCCATCCCATTAAATGACCTGAAGTCAGAAGTATCACCACGGATTTCAGCAGAGGACCTGATTGAC
  TTGTGTGAGCTCACAGTGACAGGCCACTTCAAAACACCCAGCAAGAAAACAAAGTCCAGTAAACCAAAGC
  TCCTGGTGGTTGACATCCGGAATAGTGAAGACTTTATTCGTGGTCACATTTCAGGAAGCATCAACATTCC
  ATTCAGTGCTGCCTTCACTGCAGAAGGGGAGCTTACCCAGGGCCCTTACACTGCTATGCTCCAGAACTTC
  AAAGGGAAGGTCATTGTCATCGTGGGGCATGTGGCAAAACACACAGCTGAGTTTGCAGCTCACCTTGTGA
  AGATGAAATATCCAAGAATCTGTATTCTAGATGGTGGCATTAATAAAATAAAGCCAACAGGCCTCCTCAC
  CATCCCATCTCCTCAAATATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001163435
• ORF Size: 2682 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001163435.2, NP_001156907.1
• RefSeq Size: 5309
• RefSeq ORF: 2682
• Locus ID: 93627
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a protein that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. The encoded protein is thought to play a role in actin organization, cell growth and cell proliferation by regulating the mammalian target of the rapamycin (mTOR) signaling pathway. This protein may also be involved in the transcriptional regulation of the components of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
  Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 2 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.