KDM4C (NM_001146694) Human Untagged Clone

CAT#: SC327268

KDM4C (untagged)-Human lysine (K)-specific demethylase 4C (KDM4C) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KDM4C
• Synonyms: bA146B14.1; GASC1; JHDM3C; JMJD2C; TDRD14C
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001146694, the custom clone sequence may differ by one or more nucleotides
  ATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCAGCTGTAAGATAATGACCTTCAGA
  CCCTCCATGGAGGAGTTCCGGGAGTTCAACAAATACCTTGCATACATGGAGTCTAAAGGA
  GCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCCTAAGGAGTGGAAGCCAAGACAGTGC
  TATGATGACATTGATAATTTGCTCATTCCAGCACCAATTCAGCAGATGGTCACAGGGCAG
  TCAGGACTGTTCACTCAGTACAACATCCAGAAAAAAGCGATGACTGTGAAGGAGTTCAGG
  CAGCTGGCCAACAGTGGCAAATATTGTACTCCAAGATACTTGGATTACGAAGATTTGGAG
  CGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTATCTATGGTGCAGATATTAATGGG
  AGCATATATGATGAGGGTGTGGATGAATGGAACATAGCTCGCCTCAATACAGTCTTGGAT
  GTGGTTGAAGAAGAGTGTGGCATTTCTATTGAGGGTGTAAATACCCCATATCTCTATTTT
  GGCATGTGGAAGACCACGTTTGCATGGCACACCGAAGACATGGACCTCTATAGCATTAAT
  TATCTCCACTTTGGAGAGCCCAAGTCTTGGTATGCTATACCTCCGGAGCATGGAAAACGA
  CTTGAAAGACTAGCTCAAGGTTTTTTCCCAAGCAGCTCCCAAGGGTGTGATGCATTTCTT
  CGCCACAAGATGACATTGATTTCTCCATCAGTATTGAAGAAATATGGTATTCCCTTTGAC
  AAGATAACCCAGGAGGCTGGAGAATTCATGATCACTTTCCCATATGGCTACCATGCTGGT
  TTTAATCATGGTTTCAACTGTGCAGAATCTACAAATTTTGCTACTGTCAGATGGATTGAC
  TATGGAAAAGTTGCCAAATTGTGCACTTGCAGGAAAGACATGGTGAAGATTTCAATGGAT
  ATCTTTGTGAGGAAATTTCAGCCAGACAGATATCAGCTTTGGAAACAAGGAAAGGATATA
  TACACCATTGATCACACGAAGCCTACTCCAGCATCCACCCCTGAAGTAAAAGCATGGCTG
  CAGAGGAGGAGGAAAGTAAGAAAAGCATCCCGAAGCTTCCAGTGTGCTAGGTCTACCTCT
  AAAAGGCCTAAGGCTGATGAGGAAGAGGAAGTGTCAGATGAAGTCGATGGGGCAGAGGTC
  CCTAACCCCGACTCAGTCACAGATGACCTCAAGGTCAGTGAAAAGTCAGAAGCAGCAGTG
  AAGCTGAGGAACACAGAAGCATCTTCAGAAGAAGAGTCATCTGCTAGCAGGATGCAGGTG
  GAGCAGAATTTATCAGATCATATCAAACTCTCAGGAAACAGCTGCTTAAGTACATCTGTA
  ACAGAAGACATAAAAACTGAGGATGACAAAGCTTATGCATATAGAAGTGTACCTTCTATA
  TCCAGTGAGGCTGATGATTCCATTCCATTGTCTAGTGGCTATGAGAAGCCCGAGAAATCA
  GACCCATCCGAGCTTTCATGGCCAAAGTCACCTGAGTCATGCTCATCAGTGGCAGAGAGT
  AATGGTGTGTTAACAGAGGGAGAAGAGAGTGATGTGGAGAGCCATGGGAATGGCCTTGAA
  CCTGGGGAAATCCCAGCGGTCCCCAGTGGAGAGAGAAATAGCTTCAAAGTCCCCAGTATA
  GCAGAGGGAGAGAACAAAACCTCTAAGAGTTGGCGCCATCCACTTAGCAGGCCTCCAGCA
  AGATCTCCGATGACTCTTGTGAAGCAGCAGGCGCCAAGTGATGAAGAATTGCCTGAGGTT
  CTGTCCATTGAGGAGGAAGTGGAAGAAACAGAGTCTTGGGCGAAACCTCTCATCCACCTT
  TGGCAGACGAAGTCCCCTAACTTCGCAGCTGAGCAAGAGTATAATGCAACAGTGGCCAGG
  ATGAAGCCACACTGTGCCATCTGCACTCTGCTCATGCCGTACCACAAGCCAGATAGCAGC
  AATGAAGAAAATGATGCTAGATGGGAGACAAAATTAGATGAAGTCGTTACATCGGAGGGA
  AAGACTAAGCCCCTCATACCAGAGATGTGTTTTATTTATAGTGAAGAAAATATAGAATAT
  TCTCCACCCAATGCCTTCCTTGAAGAGGATGGAACAAGTCTCCTTATTTCCTGTGCAAAG
  TGCTGCGTACGGGTTCATGCAAGTTGTTATGGTATTCCTTCTCATGAGATCTGTGATGGA
  TGGCTGTGTGCCCGGTGCAAAAGAAATGCGTGGACAGCAGAATGCTGTCTCTGCAATTTG
  AGAGGAGGTGCTCTTAAGCAAACGAAGAACAATAAGTGGGCCCATGTCATGTGCGCCGTT
  GCGGTCCCAGAAGTTCGATTCACTAATGTCCCAGAAAGGACACAAATAGATGTAGGCAGA
  ATACCTTTACAGAGGTTAAAATTGAAATGCATCTTCTGCAGACACCGGGTTAAGAGGGTC
  TCTGGAGCCTGCATCCAGTGTTCCTACGGTCGCTGCCCGGCCTCCTTCCATGTCACTTGT
  GCCCATGCTGCTGGGGTACTGATGGAGCCTGATGACTGGCCTTATGTGGTGAACATTACA
  TGCTTTCGACATAAGGTCAACCCCAACGTGAAGTCCAAGGCTTGCGAGAAGGTCATTTCC
  GTGGGTCAAACGGTCATCACGAAGCATCGGAACACCCGGTATTACAGTTGCAGAGTGATG
  GCTGTGACATCGCAGACCTTCTATGAGGTCATGTTTGATGATGGCTCCTTTAGCAGAGAC
  ACATTTCCTGAGGATATCGTGAGCCGAGACTGTCTGAAGCTGGGCCCACCTGCTGAGGGA
  GAAGTCGTCCAAGTCAAGTGGCCCGATGGCAAACTCTATGGAGCAAAATATTTTGGATCA
  AATATTGCCCACATGTACCAGGTTGAGTTTGAAGATGGATCCCAGATAGCAATGAAGAGA
  GAGGACATCTACACTTTAGATGAAGAGTTACCCAAGAGAGTGAAAGCTCGATTTGTAAGT
  GCTGGCAGATGCCACTTGGGGACCTGCCAAGTGAATTCCTTGTCCTCACCTCATGTTTCC
  CAAGCCCAGCAGGAAACATACTTGGGCTTTTGGATTAATTCTAAAAAAAGCCAATGCAAC
  ATTTTCCTTAGTGGAACCTAT
  
• Restriction Sites: Please inquire
• ACCN: NM_001146694
• ORF Size: 3144 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001146694.1, NP_001140166.1
• RefSeq Size: 4616
• RefSeq ORF: 3144
• Locus ID: 23081
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1, that results in a frameshift. It encodes isoform 2, which has a shorter and distinct C-terminus compared to isoform 1.