RASGRP3 (NM_015376) Human Untagged Clone

CAT#: SC327632

RASGRP3 (untagged)-Human RAS guanyl releasing protein 3 (calcium and DAG-regulated) (RASGRP3) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RASGRP3
• Synonyms: GRP3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015376, the custom clone sequence may differ by one or more nucleotides
  ATGGGATCAAGTGGCCTTGGGAAAGCAGCAACATTAGATGAACTGCTGTGCACTTGCATT
  GAGATGTTTGATGACAATGGAGAGCTGGATAATAGTTATTTGCCAAGAATAGTTCTACTG
  ATGCACCGATGGTATTTATCTTCCACTGAATTGGCAGAAAAACTTCTCTGCATGTATCGA
  AATGCCACTGGAGAAAGCTGCAATGAATTTCGATTAAAGATCTGCTACTTCATGAGGTAC
  TGGATTCTGAAGTTTCCTGCAGAGTTTAATTTGGATCTTGGTTTGATTCGTATGACTGAG
  GAATTTCGGGAAGTAGCTAGTCAACTAGGATATGAAAAACACGTCAGCCTCATCGACATA
  TCCAGCATTCCTTCCTATGACTGGATGAGAAGAGTCACACAGAGGAAAAAAGTATCCAAG
  AAGGGAAAAGCCTGTCTGCTGTTTGACCATCTGGAGCCCATTGAATTGGCTGAGCACCTC
  ACTTTTCTGGAGCATAAATCTTTTAGAAGGATCTCATTCACTGATTACCAAAGCTATGTC
  ATCCATGGCTGCCTGGAGAATAATCCAACCTTGGAAAGATCGATTGCTTTATTTAATGGA
  ATCTCTAAGTGGGTCCAGTTGATGGTTCTTAGCAAACCAACCCCCCAGCAAAGGGCAGAA
  GTCATCACAAAGTTTATCAATGTTGCAAAGAAGCTCCTTCAGCTCAAAAATTTTAACACC
  CTGATGGCAGTGGTGGGAGGCCTCAGTCATAGTTCCATTTCACGCCTCAAAGAGACCCAT
  TCTCATCTTTCTTCAGAAGTTACAAAGAACTGGAATGAAATGACAGAGTTGGTCTCCTCC
  AACGGCAATTACTGCAATTACCGCAAGGCCTTTGCCGACTGCGATGGCTTCAAAATCCCC
  ATCCTTGGAGTACACTTGAAAGACTTGATAGCTGTCCATGTCATTTTCCCAGACTGGACA
  GAGGAGAACAAAGTGAACATTGTGAAAATGCACCAGCTCTCCGTTACCCTGAGTGAACTA
  GTCTCCCTGCAGAATGCCTCTCACCACTTAGAACCCAACATGGATTTGATCAACCTGCTC
  ACGCTTTCCCTGGACCTCTATCACACTGAAGATGATATTTACAAACTGTCACTGGTGCTG
  GAGCCTAGAAATTCTAAATCGCCTACCTCCCCTACGACGCCCAACAAGCCTGTGGTACCC
  CTGGAGTGGGCATTAGGGGTGATGCCAAAGCCAGACCCCACGGTCATCAACAAGCACATA
  AGGAAATTAGTGGAGTCTGTATTTAGAAACTATGATCACGACCATGATGGGTACATTTCC
  CAAGAGGACTTTGAAAGTATAGCTGCCAATTTTCCCTTCTTGGATTCCTTCTGTGTTCTG
  GACAAAGATCAGGATGGCCTAATTAGTAAAGATGAAATGATGGCTTACTTCCTGAGAGCT
  AAATCCCAACTACACTGTAAAATGGGACCAGGATTTATCCATAATTTTCAGGAGATGACC
  TATCTCAAGCCAACCTTCTGCGAACACTGTGCGGGATTTCTCTGGGGCATAATCAAGCAA
  GGATACAAATGCAAAGACTGTGGAGCCAATTGTCACAAACAGTGCAAAGACCTCCTGGTT
  CTGGCCTGCAGGAGATTTGCCCGGGCGCCCTCCTTGAGCAGTGGTCATGGGTCACTGCCT
  GGAAGCCCCTCGCTGCCCCCAGCGCAGGATGAGGTGTTTGAGTTCCCTGGAGTCACTGCT
  GGACACAGGGATTTAGACAGCAGAGCCATCACACTGGTTACAGGCTCTTCTCGCAAGATC
  TCTGTGAGGCTACAGAGGGCCACCACCAGCCAGGCCACCCAGACTGAACCTGTCTGGTCA
  GAGGCTGGCTGGGGGGACTCGGGGTCCCACACCTTCCCTAAAATGAAATCCAAGTTCCAT
  GACAAAGCAGCAAAGGACAAAGGCTTTGCCAAATGGGAAAATGAGAAGCCCAGGGTGCAT
  GCTGGTGTGGATGTTGTAGACCGGGGCACGGAGTTTGAACTTGACCAGGATGAAGGAGAA
  GAGACCAGACAGGATGGTGAGGATGGC
  
• Restriction Sites: Please inquire
• ACCN: NM_015376
• ORF Size: 2070 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015376.2, NP_056191.1
• RefSeq Size: 4353
• RefSeq ORF: 2070
• Locus ID: 25780
• Domains: RasGEFN, RasGEF, EFh, DAG_PE-bind
• Protein Pathways: B cell receptor signaling pathway, MAPK signaling pathway
• Gene Summary: The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]
  Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame acceptor splice site at an internal coding exon compared to variant 1. This results in an isoform (2) which is 1 aa shorter than isoform 1. Variants 3 and 7-10 all encode the same isoform (2).