TCTN1 (NM_001173976) Human Untagged Clone

CAT#: SC328794

TCTN1 (untagged)-Human tectonic family member 1 (TCTN1) transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TCTN1
• Synonyms: JBTS13; TECT1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001173976, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATCACAGCTCACTGCAGCCTCGACCTCCTAGGCTCAGTTGCTGTTCTCTGTGTCTGTGACTTATCCC
  CAGCACAGTGTGACATCAACTGCTGCTGTGATCCCGACTGCAGCTCCGTGGATTTCAGTGTCTTTTCTGC
  CTGCTCAGTTCCAGTTGTCACGGGCGACAGCCAGTTTTGTAGTCAAAAAGCAGTCATCTATTCATTGAAT
  TTTACAGCAAACCCACCTCAAAGAGTATTTGAACTTGTTGACCAGATTAATCCATCTATTTTCTGCATTC
  ATATTACAAACTATAAACCTGCATTATCCTTTATTAATCCAGAAGTACCTGATGAAAACAATTTTGATAC
  ATTGATGAAAACATCTGATGGTTTTACATTGAATGCTGAATCATATGTTTCCTTCACAACCAAACTGGAT
  ATTCCTACTGCTGCTAAATATGAGTATGGGGTTCCTCTGCAGACTTCAGATTCGTTTCTGAGATTTCCTT
  CGTCCCTGACATCATCTCTGTGCACTGATAATAACCCTGCAGCGTTTCTGGTGAACCAGGCTGTTAAGTG
  CACCAGAAAAATAAATTTAGAACAGTGTGAAGAAATTGAAGCCCTCAGCATGGCTTTTTACAGCAGCCCG
  GAAATTCTGAGGGTACCTGATTCAAGAAAAAAGGTCCCTATCACTGTTCAGTCCATCGTCATTCAGTCTC
  TAAATAAAACGCTCACCCGACGGGAGGACACTGATGTGCTGCAGCCGACTCTCGTCAACGCTGGACACTT
  TAGCCTTTGCGTGAATGTTGTTCTTGAGGTAAAGTACAGCCTCACATACACAGATGCAGGTGAAGTCACC
  AAAGCTGATCTCTCATTCGTTCTGGGGACAGTTAGCAGCGTAGTGGTCCCACTGCAGCAAAAGTTTGAAA
  TTCATTTTCTTCAGGAAAATACCCAGCCAGTCCCTCTCAGTGGAAACCCTGGTTATGTCGTGGGGCTCCC
  ATTAGCTGCTGGATTCCAGCCTCATAAGGGTGGAGCTCTCCCGTGTCAGCTCGTAGCACAGAAGGTGAAG
  AGCCTGCTGTGGGGCCAGGGCTTCCCAGATTACGTGGCCCCTTTTGGAAATTCCCAGGCCCAGGACATGC
  TGGACTGGGTGCCCATCCACTTCATCACCCAGTCATTCAACAGGAAGCATTTTGTTTTGCAGGATTCCTG
  CCAGCTCCCAGGGGCTTTGGTTATAGAAGTGAAGTGGACTAAATACGGATCCCTGCTGAATCCACAGGCC
  AAAATAGTCAATGTAACTGCAAATCTAATTTCATCCTCCTTTCCTGAGGCCAACTCAGGAAATGAAAGGA
  CGATTCTTATTTCCACTGCGGTTACTTTTGTGGATGTGTCTGCACCTGCAGAGGCAGGCTTCAGAGCTCC
  ACCAGCCATCAATGCCAGGCTGCCCTTTAACTTCTTCTTCCCGTTTGTTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001173976
• ORF Size: 1452 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001173976.1, NP_001167447.1
• RefSeq Size: 1969
• RefSeq ORF: 1452
• Locus ID: 79600
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (5) includes an alternate exon in the 5' region, initiates translation at an alternate start codon, and lacks an in-frame exon and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting isoform (5) has a distinct N-terminus and is shorter than isoform 1.