FKLF / KLF11 (KLF11) (NM_001177716) Human Untagged Clone

CAT#: SC328812

KLF11 (untagged)-Human Kruppel-like factor 11 (KLF11) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KLF11
• Synonyms: FKLF; FKLF1; MODY7; TIEG2; Tieg3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001177716, the custom clone sequence may differ by one or more nucleotides
  ATGGACATATGTGAGTCCATCCTGGAGAGGAAGCGGCATGACAGCGAAAGGTCTACTTGC
  AGCATCTTGGAGCAGACAGACATGGAAGCTGTCGAGGCTCTTGTTTGTATGAGCTCCTGG
  GGTCAAAGATCCCAGAAAGGTGACCTGTTGCGGATAAGACCCCTCACGCCTGTCTCTGAC
  TCTGGGGATGTCACCACCACTGTGCATATGGATGCAGCCACACCTGAACTACCAAAAGAC
  TTCCATTCTTTATCGACTCTGTGCATAACTCCTCCTCAGAGCCCTGATCTCGTGGAGCCA
  TCGACAAGGACACCTGTTTCTCCCCAAGTAACAGATTCCAAAGCATGTACAGCCACGGAT
  GTTCTCCAGTCCTCTGCCGTAGTGGCCAGAGCTCTGAGCGGGGGCGCGGAGAGGGGCTTG
  CTGGGTTTGGAGCCAGTGCCCAGCTCTCCCTGCAGGGCCAAGGGGACTAGCGTGATCCGA
  CACACTGGGGAGAGCCCTGCTGCCTGCTTTCCCACCATCCAGACTCCAGATTGCCGGCTT
  TCTGACAGCAGAGAAGGAGAAGAGCAGCTTCTGGGACACTTTGAAACTTTGCAGGACACA
  CACCTCACGGACAGTTTACTCAGCACTAACTTGGTGTCCTGTCAGCCCTGCTTGCACAAG
  TCTGGTGGCCTGCTGCTCACTGACAAAGGCCAGCAGGCAGGGTGGCCTGGTGCAGTTCAG
  ACTTGCTCACCAAAGAATTATGAAAATGACCTGCCCAGGAAAACCACCCCTCTGATTTCT
  GTCTCTGTCCCTGCTCCCCCTGTCCTTTGCCAGATGATCCCTGTGACTGGACAAAGTAGC
  ATGTTACCAGCTTTTTTGAAGCCCCCTCCCCAGTTGTCTGTGGGGACTGTGAGACCCATC
  CTAGCTCAGGCTGCTCCAGCGCCTCAACCTGTGTTCGTGGGACCTGCTGTGCCTCAGGGA
  GCTGTGATGTTGGTCCTGCCCCAGGGAGCCCTCCCTCCGCCTGCCCCCTGTGCAGCCAAT
  GTCATGGCTGCCGGGAATACCAAGTTGTTGCCCCTTGCCCCTGCTCCAGTGTTCATCACC
  TCTAGCCAAAACTGTGTCCCTCAGGTAGACTTTTCCCGAAGGAGGAACTATGTTTGCAGC
  TTCCCAGGTTGCCGGAAGACCTACTTCAAAAGTTCCCACCTTAAGGCCCATCTTCGCACT
  CACACAGGGGAGAAGCCTTTCAACTGCAGCTGGGATGGCTGTGATAAAAAGTTTGCTCGT
  TCGGATGAGCTGTCACGCCACCGCAGAACTCACACAGGGGAGAAGAAGTTTGTGTGCCCG
  GTGTGTGACCGACGTTTCATGCGCAGTGACCACCTGACGAAGCATGCCCGGCGCCACATG
  ACGACCAAGAAGATCCCAGGCTGGCAGGCAGAGGTTGGCAAGCTGAACAGAATCGCCTCT
  GCAGAGAGCCCGGGGAGCCCACTGGTGAGCATGCCAGCCTCTGCCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001177716
• ORF Size: 1488 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001177716.1, NP_001171187.1
• RefSeq Size: 3906
• RefSeq ORF: 1488
• Locus ID: 8462
• Protein Families: Transcription Factors
• Gene Summary: The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
  Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.