GGA3 (NM_001172704) Human Untagged Clone

CAT#: SC328958

GGA3 (untagged)-Human golgi-associated gamma adaptin ear containing ARF binding protein 3 (GGA3) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GGA3
• Synonyms: KIAA0154
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001172704, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCTGCCAGAAGAAGCAAAGATCAAAGACGCCTACCACATGCTGAAGAGACAGGGCATAGTGCAGT
  CTGACCCACCAATTCCTGTGGATAGGACGCTGATCCCCTCTCCACCACCTCGTCCCAAAAACCCTGTTTT
  TGATGATGAGGAGAAGTCCAAGCTTTTAGCCAAGCTGCTGAAAAGCAAAAACCCAGATGACCTGCAGGAG
  GCCAACAAGCTCATCAAGTCCATGGTGAAGGAAGACGAGGCACGGATCCAGAAGGTGACCAAGCGTCTGC
  ACACGTTAGAGGAAGTTAACAACAACGTGAGACTGCTCAGTGAGATGCTGCTTCATTACAGCCAGGAGGA
  CTCTTCGGACGGGGACAGAGAGCTGATGAAGGAGCTGTTTGATCAGTGTGAGAACAAGAGGCGGACTTTA
  TTTAAACTCGCCAGTGAGACTGAGGACAATGATAACAGTTTGGGGGACATCCTGCAAGCCAGTGACAACC
  TCTCCCGGGTCATCAACTCTTACAAAACAATTATTGAAGGGCAGGTCATCAATGGCGAGGTGGCTACCTT
  AACCCTGCCTGACTCGGAAGGAAACAGTCAGTGCAGTAACCAAGGCACGCTCATCGACCTTGCGGAGCTG
  GACACGACCAACAGTTTGTCCTCCGTGTTGGCCCCAGCACCTACTCCACCCTCCTCAGGCATCCCAATCC
  TCCCTCCACCACCCCAGGCCTCAGGACCTCCACGGAGCCGCTCCTCTAGCCAGGCCGAGGCCACCCTGGG
  GCCCAGCAGCACAAGCAACGCCCTCTCCTGGCTGGACGAGGAGCTACTCTGCTTGGGCCTCGCCGACCCA
  GCCCCTAATGTTCCTCCCAAAGAGTCAGCTGGGAACAGCCAGTGGCACCTGCTCCAGAGGGAACAGTCCG
  ACCTGGACTTCTTCAGCCCCAGGCCGGGGACCGCTGCCTGTGGCGCCTCCGATGCTCCTCTGCTCCAGCC
  CTCAGCCCCCTCCTCAAGCAGCTCCCAAGCTCCACTGCCGCCTCCCTTCCCAGCTCCTGTGGTCCCAGCC
  AGTGTTCCTGCCCCCAGTGCGGGCTCCTCCTTGTTTTCTACTGGAGTGGCCCCAGCCTTGGCCCCAAAAG
  TTGAGCCCGCAGTCCCTGGGCACCATGGCTTGGCGTTGGGCAACAGCGCGCTGCACCACCTGGATGCCCT
  CGATCAGCTTCTAGAAGAGGCCAAAGTGACCTCGGGCTTGGTGAAACCCACTACCTCCCCTCTCATCCCC
  ACCACCACCCCAGCCAGGCCCCTCCTGCCCTTCTCCACGGGGCCCGGCAGCCCGCTCTTCCAGCCACTGA
  GTTTCCAGTCCCAGGGCAGCCCCCCGAAGGGGCCTGAGCTCTCCCTGGCCAGCATCCACGTGCCCCTGGA
  ATCGATCAAGCCTAGCAGTGCCCTTCCTGTGACAGCCTACGATAAAAACGGCTTCCGCATCCTCTTCCAC
  TTTGCCAAGGAGTGTCCCCCAGGACGACCTGACGTGCTGGTGGTGGTGGTGTCCATGCTGAACACGGCTC
  CCTTACCTGTCAAGAGCATCGTGCTGCAGGCTGCAGTGCCCAAGTCAATGAAAGTGAAGTTGCAGCCACC
  TTCTGGGACAGAACTCTCTCCATTTAGCCCCATCCAGCCACCTGCAGCCATCACCCAGGTCATGTTGCTG
  GCCAATCCACTGAAGAAGCAGGTACTCAGCTTTCTGGGAAAAGCGTGCCTCCAGCCGTGGGGACAGGCCA
  TCCTACTGACTACCTCTTGCTTGGCATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001172704
• ORF Size: 1779 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001172704.2, NP_001166175.1
• RefSeq Size: 2991
• RefSeq ORF: 1779
• Locus ID: 23163
• Protein Families: Druggable Genome
• Protein Pathways: Lysosome
• Gene Summary: This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
  Transcript Variant: This variant (2) contains alternate 5' exon structure and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, and it also contains an alternate 3' terminal exon that results in an alternate 3' coding region, compared to variant long. The encoded isoform (2) is shorter at the N-terminus and has a distinct C-terminus, compared to isoform long.