FOXP2 (NM_001172766) Human Untagged Clone

CAT#: SC329089

FOXP2 (untagged)-Human forkhead box P2 (FOXP2) transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FOXP2
• Synonyms: CAGH44; SPCH1; TNRC10
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001172766, the custom clone sequence may differ by one or more nucleotides
  ATGATGCAGGAATCTGCGACAGAGACAATAAGCAACAGTTCAATGAATCAAAATGGAATG
  AGCACTCTAAGCAGCCAATTAGATGCTGGCAGCAGAGATGGAAGATCAAGTGGTGACACC
  AGCTCTGAAGTAAGCACAGTAGAACTGCTGCATCTGCAACAACAGCAGGCTCTCCAGGCA
  GCAAGACAACTTCTTTTACAGCAGCAAACAAGTGGATTGAAATCTCCTAAGAGCAGTGAT
  AAACAGAGACCACTGCAGGTGCCTGTGTCAGTGGCCATGATGACTCCCCAGGTGATCACC
  CCTCAGCAAATGCAGCAGATCCTTCAGCAACAAGTCCTGTCTCCTCAGCAGCTACAAGCC
  CTTCTCCAACAACAGCAGGCTGTCATGCTGCAGCAGCAACAACTACAAGAGTTTTACAAG
  AAACAGCAAGAGCAGTTACATCTTCAGCTTTTGCAGCAGCAGCAGCAACAGCAGCAGCAG
  CAACAACAGCAGCAACAACAGCAGCAGCAACAACAACAACAACAGCAGCAACAACAGCAG
  CAGCAGCAGCAACAGCAGCAGCAGCAGCAACAGCATCCTGGAAAGCAAGCGAAAGAGCAG
  CAGCAGCAGCAGCAGCAACAGCAATTGGCAGCCCAGCAGCTTGTCTTCCAGCAGCAGCTT
  CTCCAGATGCAACAACTCCAGCAGCAGCAGCATCTGCTCAGCCTTCAGCGTCAGGGACTC
  ATCTCCATTCCACCTGGCCAGGCAGCACTTCCTGTCCAATCGCTGCCTCAAGCTGGCTTA
  AGTCCTGCTGAGATTCAGCAGTTATGGAAAGAAGTGACTGGAGTTCACAGTATGGAAGAC
  AATGGCATTAAACATGGAGGGCTAGACCTCACTACTAACAATTCCTCCTCGACTACCTCC
  TCCAACACTTCCAAAGCATCACCACCAATAACTCATCATTCCATAGTGAATGGACAGTCT
  TCAGTTCTAAGTGCAAGACGAGACAGCTCGTCACATGAGGAGACTGGGGCCTCTCACACT
  CTCTATGGCCATGGAGTTTGCAAATGGCCAGGCTGTGAAAGCATTTGTGAAGATTTTGGA
  CAGTTTTTAAAGCACCTTAACAATGAACACGCATTGGATGACCGAAGCACTGCTCAGTGT
  CGAGTGCAAATGCAGGTGGTGCAACAGTTAGAAATACAGCTTTCTAAAGAACGCGAACGT
  CTTCAAGCAATGATGACCCACTTGCACATGCGACCCTCAGAGCCCAAACCATCTCCCAAA
  CCTCTAAATCTGGTGTCTAGTGTCACCATGTCGAAGAATATGTTGGAGACATCCCCACAG
  AGCTTACCTCAAACCCCTACCACACCAACGGCCCCAGTCACCCCGATTACCCAGGGACCC
  TCAGTAATCACCCCAGCCAGTGTGCCCAATGTGGGAGCCATACGAAGGCGACATTCAGAC
  AAATACAACATTCCCATGTCATCAGAAATTGCCCCAAACTATGAATTTTATAAAAATGCA
  GATGTCAGACCTCCATTTACTTATGCAACTCTCATAAGGCAGGCTATCATGGAGTCATCT
  GACAGGCAGTTAACACTTAATGAAATTTACAGCTGGTTTACACGGACATTTGCTTACTTC
  AGGCGTAATGCAGCAACTTGGAAGAATGCAGTACGTCATAATCTTAGCCTGCACAAGTGT
  TTTGTTCGAGTAGAAAATGTTAAAGGAGCAGTATGGACTGTGGATGAAGTAGAATACCAG
  AAGCGAAGGTCACAAAAGATAACAGGAAGTCCAACCTTAGTAAAAAATATACCTACCAGT
  TTAGGCTATGGAGCAGCTCTTAATGCCAGTTTGCAGGCTGCCTTGGCAGAGAGCAGTTTA
  CCTTTGCTAAGTAATCCTGGACTGATAAATAATGCATCCAGTGGCCTACTGCAGGCCGTC
  CACGAAGACCTCAATGGTTCTCTGGATCACATTGACAGCAATGGAAACAGTAGTCCGGGC
  TGCTCACCTCAGCCGCACATACATTCAATCCACGTCAAGGAAGAGCCAGTGATTGCAGAG
  GATGAAGACTGCCCAATGTCCTTAGTGACAACAGCTAATCACAGTCCAGAATTAGAAGAC
  GACAGAGAGATTGAAGAAGAGCCTTTATCTGAAGATCTGGAATGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001172766
• ORF Size: 2145 bp
• Insert Size: 6370
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001172766.1, NP_001166237.1
• RefSeq Size: 6370
• RefSeq ORF: 2145
• Locus ID: 93986
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
  Transcript Variant: This variant (5) lacks an in-frame exon and uses an alternate in-frame splice site in the coding region, compared to variant 2. The resulting isoform (V) is shorter than isoform II. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.