TJP2 (NM_001170414) Human Untagged Clone

CAT#: SC329259

TJP2 (untagged)-Human tight junction protein 2 (zona occludens 2) (TJP2) transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TJP2
• Synonyms: C9DUPq21.11; DFNA51; DUP9q21.11; PFIC4; X104; ZO2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001170414, the custom clone sequence may differ by one or more nucleotides
  ATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGA
  TTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCA
  ATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGAC
  AGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAG
  CAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAG
  GTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATG
  GACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGC
  CATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGG
  GCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGG
  GGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGG
  GGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGG
  AGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGG
  GCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGA
  AGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCG
  GGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTT
  GGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAAC
  CTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTA
  ACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGA
  GACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAA
  GATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTAT
  TCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAG
  GACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGG
  GATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCC
  CCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAA
  GCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTC
  CGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCG
  GCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACACAGGATTTC
  AGAGGATTAGTGCGGGAGGATGCCGTTCTCTACCTGTTAGAAATCCCTAAAGGTGAAATG
  GTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGAGACATCCTGGCTTGTGGCAGA
  GGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCACAGAGCCTG
  GCCTTCACCAGAGGGGAGGTCTTCCGAGTGGTAGACACACTGTATGACGGCAAGCTGGGC
  AACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAAGGCTTAATCCCCAACAAGAGC
  AGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGACCGGGCA
  GATTTCTGGAGAATGCGTGGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGGAAAAGTCGG
  GAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTCCCAGCTTATGAGAGGGTTTTG
  CTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGATATAGCA
  ATGGAAAAATTGGCTAATGAGTTACCTGACTGGTTTCAAACTGCTAAAACGGAACCAAAA
  GATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTAAATACCGTGAGGCAAATTATT
  GAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTGTTGAATTAC
  ACCCAGTGGTTCCCAATTGTGATTTTTTTCAACCCAGACTCCAGACAAGGTGTCAAAACC
  ATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCTCGAAAGTTATTTGATCAAGCC
  AACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCTACAATCAACCTAAATTCAGCC
  AATGATAGCTGGTTTGGCAGCTTAAAGGACACTATTCAGCATCAGCAAGGAGAAGCGGTT
  TGGGTCTCTGAAGGAAAGATGGAAGGGATGGATGATGACCCCGAAGACCGCATGTCCTAC
  TTAACCGCCATGGGCGCGGACTATCTGAGTTGCGACAGCCGCCTCATCAGTGACTTTGAA
  GACACGGACGGTGAAGGAGGCGCCTACACTGACAATGAGCTGGATGAGCCAGCCGAGGAG
  CCGCTGGTGTCGTCCATCACCCGCTCCTCGGAGCCGGTGCAGCACGAGGAGATCGAAATT
  GCCCAGAAGCATCCTGATATCTATGCAGTTCCAATCAAAACGCACAAGCCAGACCCTGGC
  ACGCCCCAGCACACGAGTTCCAGACCCCCTGAGCCACAGAAAGCTCCTTCCAGACCTTAT
  CAGGATACCAGAGGAAGTTATGGCAGTGATGCCGAGGAGGAGGAGTACCGCCAGCAGCTG
  TCAGAACACTCCAAGCGCGGTTACTATGGCCAGTCTGCCCGATACCGGGACACAGAATTA
  TAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001170414
• ORF Size: 3063 bp
• Insert Size: 4129
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001170414.1, NP_001163885.1
• RefSeq Size: 4129
• RefSeq ORF: 3063
• Locus ID: 9414
• Protein Pathways: Tight junction, Vibrio cholerae infection
• Gene Summary: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
  Transcript Variant: This variant (5) has multiple differences, compared to variant 1. These differences include a distinct 5' UTR and translation initiation at a downstream start codon, compared to variant 1. The encoded isoform (5) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.