L Kynurenine Hydrolase (KYNU) (NM_001199241) Human Untagged Clone

CAT#: SC329501

KYNU (untagged) - Homo sapiens kynureninase (KYNU), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KYNU
• Synonyms: KYNUU; VCRL2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001199241, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGCCTTCATCTCTTGAGCTGCCGGCTGACACAGTGCAGCGCATTGCGGCTGAACTCAAATGCCACC
  CAACGGATGAGAGGGTGGCTCTCCACCTAGATGAGGAAGATAAGCTGAGGCACTTCAGGGAGTGCTTTTA
  TATTCCCAAAATACAGGATCTGCCTCCAGTTGATTTATCATTAGTGAATAAAGATGAAAATGCCATCTAT
  TTCTTGGGAAATTCTCTTGGCCTTCAACCAAAAATGGTTAAAACATATCTTGAAGAAGAACTAGATAAGT
  GGGCCAAAATAGCAGCCTATGGTCATGAAGTGGGGAAGCGTCCTTGGATTACAGGAGATGAGAGTATTGT
  AGGCCTTATGAAGGACATTGTAGGAGCCAATGAGAAAGAAATAGCCCTAATGAATGCTTTGACTGTAAAT
  TTACATCTTCTAATGTTATCATTTTTTAAGCCTACGCCAAAACGATATAAAATTCTTCTAGAAGCCAAAG
  CCTTCCCTTCTGATCATTATGCTATTGAGTCACAACTACAACTTCACGGACTTAACATTGAAGAAAGTAT
  GCGGATGATAAAGCCAAGAGAGGGGGAAGAAACCTTAAGAATAGAGGATATCCTTGAAGTAATTGAGAAG
  GAAGGAGACTCAATTGCAGTGATCCTGTTCAGTGGGGTGCATTTTTACACTGGACAGCACTTTAATATTC
  CTGCCATCACAAAAGCTGGACAAGCGAAGGGTTGTTATGTTGGCTTTGATCTAGCACATGCAGTTGGAAA
  TGTTGAACTCTACTTACATGACTGGGGAGTTGATTTTGCCTGCTGGTGTTCCTACAAGTATTTAAATGCA
  GGAGCAGGAGGAATTGCTGGTGCCTTCATTCATGAAAAGCATGCCCATACGATTAAACCTGCATTAGTGG
  GATGGTTTGGCCATGAACTCAGCACCAGATTTAAGATGGATAACAAACTGCAGTTAATCCCTGGGGTCTG
  TGGATTCCGAATTTCAAATCCTCCCATTTTGTTGGTCTGTTCCTTGCATGCTAGTTTAGAGATCTTTAAG
  CAAGCGACAATGAAGGCATTGCGGAAAAAATCTGTTTTGCTAACTGGCTATCTGGAATACCTGATCAAGC
  ATAACTATGGCAAAGATAAAGCAGCAACCAAGAAACCAGTTGTGAACATAATTACTCCGTCTCATGTAGA
  GGAGCGGGGGTGCCAGCTAACAATAACATTTTCTGTTCCAAACAAAGATGTTTTCCAAGAACTAGAAAAA
  AGAGGAGTGGTTTGTGACAAGCGGAATCCAAATGGCATTCGAGTGGCTCCAGTTCCTCTCTATAATTCTT
  TCCATGATGTTTATAAATTTACCAATCTGCTCACTTCTATACTTGACTCTGCAGAAACAAAAAATTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001199241
• ORF Size: 1398 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001199241.1, NP_001186170.1
• RefSeq Size: 1774
• RefSeq ORF: 1398
• Locus ID: 8942
• Protein Families: Protease
• Protein Pathways: Metabolic pathways, Tryptophan metabolism
• Gene Summary: Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
  Transcript Variant: This variant (3) represents the longest transcript variant. Variants 1 and 3 encode isoform a.