GGCT (NM_001199815) Human Untagged Clone

CAT#: SC329569

GGCT (untagged) - Homo sapiens gamma-glutamylcyclotransferase (GGCT), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GGCT
• Synonyms: C7orf24; CRF21; GCTG; GGC
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001199815, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCAACTCGGGCTGCAAGGACGTCACGGGTCCAGATGAGGAGAGTTTTCTGTACTTTGCCTACGGCA
  GCAACCTGCTGACAGAGAGGATCCACCTCCGAAACCCCTCGGCGGCGTTCTTCTGTGTGGCCCGCCTGCA
  GGATTTTAAGCTTGACTTTGGCAATTCCCAAGGCAAAACAAGTCAAACTTGGCATGGAGGGATAGCCACC
  ATTTTTCAGAGTCCTGGCGATGAAGTGTGGGGAGTAGTATGGAAAATGAACAAAAGCAATTTAAATTCTC
  TGGATGAGTGGAGAAAGAAACGTCACACTGCCTTTCAGAATCAGGGAAATCACCCTTGCAAGCACAAGAC
  AAGAATGTGGGATAGAGACCCCAAAATTCCTGTTCAGAACCTAAGCTTAGCTCTCTGTTGGCAGGCCCAA
  TCAGGTCATGGCACCTGTAATAGATTATTTGCATGGGTGCAAAAGAAAATGGTTTGCCGCTGGAGTATCA
  AGAGAAGTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001199815
• ORF Size: 501 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001199815.1, NP_001186744.1
• RefSeq Size: 1217
• RefSeq ORF: 501
• Locus ID: 79017
• Protein Pathways: Glutathione metabolism
• Gene Summary: The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.