CRMP2 (DPYSL2) (NM_001244604) Human Untagged Clone

CAT#: SC330213

DPYSL2 (untagged) - Homo sapiens dihydropyrimidinase-like 2 (DPYSL2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DPYSL2
• Synonyms: CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001244604, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAAGATGGGTTGATCAAGCAAATAGGAGAAAATCTGATTGTGCCAGGAGGAGTGAAGACCATCGAGG
  CCCACTCCCGGATGGTGATCCCCGGAGGAATTGACGTCCACACTCGTTTCCAGATGCCTGATCAGGGAAT
  GACGTCTGCTGATGATTTCTTCCAAGGAACCAAGGCGGCCCTGGCTGGGGGAACCACTATGATCATTGAC
  CACGTTGTTCCTGAGCCTGGGACAAGCCTGCTCGCTGCCTTTGACCAGTGGAGGGAATGGGCCGACAGCA
  AGTCCTGCTGTGACTACTCTCTGCATGTGGACATCAGTGAGTGGCATAAGGGCATCCAGGAGGAGATGGA
  AGCGCTTGTGAAGGATCACGGGGTAAATTCCTTCCTCGTGTACATGGCTTTCAAAGATCGCTTCCAGCTA
  ACGGATTGCCAGATTTATGAAGTACTGAGTGTGATCCGGGATATTGGCGCCATAGCCCAAGTCCACGCAG
  AAAATGGCGACATCATTGCAGAGGAGCAGCAGAGGATCCTGGATCTGGGCATCACGGGCCCCGAGGGACA
  TGTGCTGAGCCGACCTGAGGAGGTCGAGGCCGAAGCCGTGAATCGTGCCATCACCATCGCCAACCAGACC
  AACTGCCCGCTGTATATCACCAAGGTGATGAGCAAAAGCTCTGCTGAGGTCATCGCCCAGGCACGGAAGA
  AGGGAACTGTGGTGTATGGCGAGCCCATCACTGCCAGCTTGGGAACGGACGGCTCCCATTACTGGAGCAA
  GAACTGGGCCAAGGCTGCTGCCTTTGTCACCTCCCCACCCTTGAGCCCTGATCCAACCACTCCAGACTTT
  CTCAACTCCTTGCTGTCCTGTGGAGACCTCCAGGTCACGGGCAGTGCCCATTGCACGTTTAACACTGCCC
  AGAAGGCTGTAGGAAAGGACAACTTCACCCTGATTCCGGAGGGCACCAATGGCACTGAGGAGCGGATGTC
  CGTCATCTGGGACAAGGCTGTGGTCACTGGGAAGATGGATGAGAACCAGTTTGTGGCTGTGACCAGCACC
  AATGCAGCCAAAGTCTTCAACCTTTACCCCCGGAAAGGCCGCATTGCTGTGGGATCCGATGCCGACCTGG
  TCATCTGGGACCCCGACAGCGTTAAAACCATCTCTGCCAAGACACACAACAGCTCTCTCGAGTACAACAT
  CTTTGAAGGCATGGAGTGCCGCGGCTCCCCACTGGTGGTCATCAGCCAGGGGAAGATTGTCCTGGAGGAC
  GGCACCCTGCATGTCACCGAAGGCTCTGGACGCTACATTCCCCGGAAGCCCTTCCCTGATTTTGTTTACA
  AGCGTATCAAGGCAAGGAGCAGGCTGGCTGAGCTGAGAGGGGTTCCTCGTGGCCTGTATGACGGACCTGT
  GTGTGAAGTGTCTGTGACGCCCAAGACAGTCACTCCAGCCTCCTCGGCCAAGACGTCTCCTGCCAAGCAG
  CAGGCCCCACCTGTCCGGAACCTGCACCAGTCTGGATTCAGTTTGTCTGGTGCTCAGATTGATGACAACA
  TTCCCCGCCGCACCACCCAGCGTATCGTGGCGCCCCCCGGTGGCCGTGCCAACATCACCAGCCTGGGCTA
  G
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001244604
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001244604.1, NP_001231533.1
• RefSeq Size: 4297 bp
• RefSeq ORF: 1611 bp
• Locus ID: 1808
• Cytogenetics: 8p21.2
• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance
• Gene Summary: 'This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]'
  Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.