HIP1 (NM_001243198) Human Untagged Clone

CAT#: SC331969

HIP1 (untagged) - Homo sapiens huntingtin interacting protein 1 (HIP1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HIP1
• Synonyms: HIP-I; ILWEQ; SHON; SHONbeta; SHONgamma
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001243198, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGG
  TCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGACTGTCAGCATCAATAAGGC
  CATTAATACGCAGGAAGTGGCTGTAAAGGAAAAACACGCCAGAACGTGCATACTGGGCACCCACCATGAG
  AAAGGGGCACAGACCTTCTGGTCTGTTGTCAACCGCCTGCCTCTGTCTAGCAACGCAGTGCTCTGCTGGA
  AGTTCTGCCATGTGTTCCACAAACTCCTCCGAGATGGACACCCGAACGTCCTGAAGGACTCTCTGAGATA
  CAGAAATGAATTGAGTGACATGAGCAGGATGTGGGGCCACCTGAGCGAGGGGTATGGCCAGCTGTGCAGC
  ATCTACCTGAAACTGCTAAGAACCAAGATGGAGTACCACACCAAAAATCCCAGGTTCCCAGGCAACCTGC
  AGATGAGTGACCGCCAGCTGGACGAGGCTGGAGAAAGTGACGTGAACAACTTTTTCCAGTTAACAGTGGA
  GATGTTTGACTACCTGGAGTGTGAACTCAACCTCTTCCAAACAGTATTCAACTCCCTGGACATGTCCCGC
  TCTGTGTCCGTGACGGCAGCAGGGCAGTGCCGCCTCGCCCCGCTGATCCAGGTCATCTTGGACTGCAGCC
  ACCTTTATGACTACACTGTCAAGCTTCTCTTCAAACTCCACTCCTGCCTCCCAGCTGACACCCTGCAAGG
  CCACCGGGACCGCTTCATGGAGCAGTTTACAAAGTTGAAAGATCTGTTCTACCGCTCCAGCAACCTGCAG
  TACTTCAAGCGGCTCATTCAGATCCCCCAGCTGCCTGAGAACCCACCCAACTTCCTGCGAGCCTCAGCCC
  TGTCAGAACATATCAGCCCTGTGGTGGTGATCCCTGCAGAGGCCTCATCCCCCGACAGCGAGCCAGTCCT
  AGAGAAGGATGACCTCATGGACATGGATGCCTCTCAGCAGAATTTATTTGACAACAAGTTTGATGACATC
  TTTGGCAGTTCATTCAGCAGTGATCCCTTCAATTTCAACAGTCAAAATGGTGTGAACAAGGATGAGAAGG
  ACCACTTAATTGAGCGACTATACAGAGAGATCAGTGGATTGAAGGCACAGCTAGAAAACATGAAGACTGA
  GAGCCAGCGGGTTGTGCTGCAGCTGAAGGGCCACGTCAGCGAGCTGGAAGCAGATCTGGCCGAGCAGCAG
  CACCTGCGGCAGCAGGCGGCCGACGACTGTGAATTCCTGCGGGCAGAACTGGACGAGCTCAGGAGGCAGC
  GGGAGGACACCGAGAAGGCTCAGCGGAGCCTGTCTGAGATAGAAAGGAAAGCTCAAGCCAATGAACAGCG
  ATATAGCAAGCTAAAGGAGAAGTACAGCGAGCTGGTTCAGAACCACGCTGACCTGCTGCGGAAGAATGCA
  GAGGTGACCAAACAGGTGTCCATGGCCAGACAAGCCCAGGTAGATTTGGAACGAGAGAAAAAAGAGCTGG
  AGGATTCGTTGGAGCGCATCAGTGACCAGGGCCAGCGGAAGACTCAAGAACAGCTGGAAGTTCTAGAGAG
  CTTGAAGCAGGAACTTGCCACAAGCCAACGGGAGCTTCAGGTTCTGCAAGGCAGCCTGGAAACTTCTGCC
  CAGTCAGAAGCAAACTGGGCAGCCGAGTTCGCCGAGCTAGAGAAGGAGCGGGACAGCCTGGTGAGTGGCG
  CAGCTCATAGGGAGGAGGAATTATCTGCTCTTCGGAAAGAACTGCAGGACACTCAGCTCAAACTGGCCAG
  CACAGAGGAATCTATGTGCCAGCTTGCCAAAGACCAACGAAAAATGCTTCTGGTGGGGTCCAGGAAGGCT
  GCGGAGCAGGTGATACAAGACGCCCTGAACCAGCTTGAAGAACCTCCTCTCATCAGCTGCGCTGGGTCTG
  CAGATCACCTCCTCTCCACGGTCACATCCATTTCCAGCTGCATCGAGCAACTGGAGAAAAGCTGGAGCCA
  GTATCTGGCCTGCCCAGAAGACATCAGTGGACTTCTCCATTCCATAACCCTGCTGGCCCACTTGACCAGC
  GACGCCATTGCTCATGGTGCCACCACCTGCCTCAGAGCCCCACCTGAGCCTGCCGACTCACTGACCGAGG
  CCTGTAAGCAGTATGGCAGGGAAACCCTCGCCTACCTGGCCTCCCTGGAGGAAGAGGGAAGCCTTGAGAA
  TGCCGACAGCACAGCCATGAGGAACTGCCTGAGCAAGATCAAGGCCATCGGCGAGGAGCTCCTGCCCAGG
  GGACTGGACATCAAGCAGGAGGAGCTGGGGGACCTGGTGGACAAGGAGATGGCGGCCACTTCAGCTGCTA
  TTGAAACTGCCACGGCCAGAATAGAGGGTACAGCATCCCCTAAAGAGTTTTATGCCAAGAACTCTCGATG
  GACAGAAGGACTTATCTCAGCCTCCAAGGCTGTGGGCTGGGGAGCCACTGTCATGGTGGATGCAGCTGAT
  CTGGTGGTACAAGGCAGAGGGAAATTTGAGGAGCTAATGGTGTGTTCTCATGAAATTGCTGCTAGCACAG
  CCCAGCTTGTGGCTGCATCCAAGGTGAAAGCTGATAAGGACAGCCCCAACCTAGCCCAGCTGCAGCAGGC
  CTCTCGGGGAGTGAACCAGGCCACTGCCGGCGTTGTGGCCTCAACCATTTCCGGCAAATCACAGATCGAA
  GAGACAGACAACATGGACTTCTCAAGCATGACGCTGACACAGATCAAACGCCAAGAGATGGATTCTCAGG
  TTAGGGTGCTAGAGCTAGAAAATGAATTGCAGAAGGAGCGTCAAAAACTGGGAGAGCTTCGGAAAAAGCA
  CTACGAGCTTGCTGGTGTTGCTGAGGGCTGGGAAGAAGGAACAGAGGCATCTCCACCTACACTGCAAGAA
  GTGGTAACCGAAAAAGAATAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001243198
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001243198.2, NP_001230127.1
• RefSeq Size: 7903 bp
• RefSeq ORF: 2961 bp
• Locus ID: 3092
• Cytogenetics: 7q11.23
• Protein Families: Druggable Genome
• Protein Pathways: Huntington's disease
• Gene Summary: 'The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain; this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]'
  Transcript Variant: This variant (2) lacks two alternate in-frame exons, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.