EPB41L1 (NM_001258330) Human Untagged Clone

CAT#: SC332665

EPB41L1 (untagged) - Homo sapiens erythrocyte membrane protein band 4.1-like 1 (EPB41L1), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EPB41L1
• Synonyms: 4.1N; MRD11
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001258330, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTTTTCTTGGGGAGGATCAATGAGGTAGAACCTGCAAAGGGCTTAGCAGAGAGCCTAGCACCTACTG
  AGCGCTCAGTAAAGAGCCTAGACATGGAGGAGAAGGACTACAGTGAGGCCGATGGCCTTTCGGAGAGGAC
  CACGCCCAGCAAGGCCCAGAAATCGCCCCAGAAGATTGCCAAGAAATACAAGAGTGCCATCTGCCGGGTC
  ACTCTGCTTGATGCCTCGGAGTATGAGTGTGAGGTGGAGAAACATGGCCGGGGCCAGGTGCTGTTTGACC
  TGGTCTGTGAACACCTCAACCTCCTAGAGAAGGACTACTTCGGCCTGACCTTCTGTGATGCTGACAGCCA
  GAAGAACTGGCTGGACCCCTCCAAGGAGATCAAGAAGCAGATCCGGAGTAGCCCCTGGAATTTTGCCTTC
  ACAGTCAAGTTCTACCCGCCTGATCCTGCCCAGCTGACAGAAGACATCACAAGATACTACCTGTGCCTGC
  AGCTGCGGGCAGACATCATCACGGGCCGGCTGCCATGCTCCTTTGTCACGCATGCCCTACTGGGCTCCTA
  CGCTGTGCAGGCTGAGCTGGGTGACTATGATGCTGAGGAGCATGTGGGCAACTATGTCAGCGAGCTCCGC
  TTCGCCCCTAACCAGACCCGGGAGCTGGAGGAGAGGATCATGGAGCTGCATAAGACATATAGGGGGATGA
  CCCCGGGAGAAGCAGAAATCCACTTCTTAGAGAATGCCAAGAAGCTTTCCATGTACGGAGTAGACCTGCA
  CCATGCCAAGGACTCTGAGGGCATCGACATCATGTTAGGCGTTTGTGCCAATGGCCTGCTCATCTACCGG
  GACCGGCTGAGAATCAACCGCTTTGCCTGGCCCAAGATCCTCAAGATCTCCTACAAGAGGAGTAACTTCT
  ATATCAAGATCCGGCCTGGGGAGTATGAGCAATTTGAGAGCACAATTGGCTTTAAGCTCCCAAACCACCG
  GTCAGCCAAGAGACTGTGGAAGGTCTGCATCGAGCATCATACATTCTTCCGGCTGGTGTCCCCTGAGCCC
  CCACCCAAGGGCTTCCTGGTGATGGGCTCCAAGTTCCGGTACAGTGGGAGGACCCAGGCACAGACTCGCC
  AGGCCAGCGCCCTCATTGACCGGCCTGCACCCTTCTTTGAGCGTTCTTCCAGCAAACGGTACACCATGTC
  CCGCAGCCTTGATGGAGCAGAGTTCTCCCGCCCAGCCTCGGTCAGCGAGAACCATGATGCAGGGCCTGAC
  GGTGACAAGCGGGATGAGGATGGCGAGTCTGGGGGGCAACGGTCAGAGGCTGAGGAGGGAGAGGTCAGGA
  CTCCAACCAAGATCAAGGAGCTAAAGTTCTTAGACAAGCCAGAAGATGTCTTGCTGAAGCACCAGGCCAG
  CATCAATGAGCTCAAAAGGACCCTGAAGGAGCCCAACAGCAAACTCATCCACCGGGATCGAGACTGGGAA
  CGGGAGCGCAGGCTGCCCTCCTCCCCCGCCTCCCCCTCCCCCAAGGGCACCCCTGAGAAAGCCAATGAGC
  CCGTGAAAACAGAAACCATGACTGTCAGCAGTCTGGCCATTAGAAAGAAGATTGAGCCGGAGGCCGTACT
  GCAGACCAGAGTCTCCGCTATGGATAACACCCAGCAGGTTGATGGGAGTGCCTCAGTGGGGAGGGAGTTC
  ATAGCAACCACTCCCTCCATCACCACGGAGACCATATCGACCACCATGGAGAACAGTCTCAAGTCCGGGA
  AGGGGGCAGCTGCCATGATCCCAGGCCCACAGACGGTGGCCACGGAAATCCGTTCTCTTTCTCCGATCAT
  CGGGAAAGATGTCCTCACCAGCACCTACGGCGCCACTGCGGAAACCCTCTCAACCTCCACCACCACCCAT
  GTCACCAAAACTGTGAAAGGAGGGTTTTCTGAGACAAGGATCGAGAAGCGAATCATCATTACTGGGGATG
  AAGATGTCGATCAAGACCAGGCCCTGGCTTTGGCCATCAAGGAGGCCAAACTGCAGCATCCTGATATGCT
  GGTAACCAAAGCTGTCGTATACAGAGAAACAGACCCATCCCCAGAGGAGAGGGACAAGAAGCCACAGGAA
  TCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001258330
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001258330.1, NP_001245259.1
• RefSeq Size: 5745 bp
• RefSeq ORF: 2106 bp
• Locus ID: 2036
• Cytogenetics: 20q11.23
• Protein Families: Druggable Genome
• Protein Pathways: Tight junction
• Gene Summary: 'Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]'
  Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence and lacks two alternate in-frame exons compared to variant 1. The resulting isoform (d) has a shorter and distinct N-terminus and lacks two alternate internal segments compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: The 5'-most in-frame start codon is annotated for this transcript variant, which is supported by mRNA AK126875.1. It is present in a novel exon not found in other transcript variants for this gene. The annotated start codon is restricted to select higher primate species, including human, chimp, gorilla, orangutan and gibbon. It has a weak Kozak sequence and may sometimes be bypassed due to leaky scanning by ribosomes, which could result in use of a better conserved downstream start codon. There is no experimental evidence to indicate which start codon is preferentially used by this variant in vivo.