Lipin 1 (LPIN1) (NM_001261428) Human Untagged Clone
CAT#: SC332775
LPIN1 (untagged) - Homo sapiens lipin 1 (LPIN1), transcript variant 3
"NM_001261428" in other vectors (2)
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Specifications
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Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | LPIN1 |
Synonyms | PAP1 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_001261428, the custom clone sequence may differ by one or more nucleotides
ATGGGGGAACAGGACGGCATTCGCAGCTCCAGCTGGGAGACCTCGCAGGGCAAGAGCTCCCCAGACTCGG CTTGGTCATGGATTCCAATAATGAGAGACCCTGGGTGGATTCGAAATGTATGGTCTTCAAACATTAACGT GCAGACCATGAATTACGTGGGGCAGTTAGCCGGCCAGGTGTTTGTCACCGTGAAGGAGCTCTACAAGGGG CTGAATCCCGCCACACTCTCAGGGTGCATTGACATCATTGTCATCCGCCAGCCCAATGGAAACCTCCAAT GCTCCCCTTTCCACGTCCGCTTTGGGAAGATGGGGGTCCTGCGCTCCCGAGAGAAAGTGGTTGACATAGA AATCAATGGGGAATCTGTGGATTTGCATATGAAATTGGGAGATAATGGAGAAGCATTTTTTGTTCAAGAA ACAGATAATGATCAGGAAGTTATCCCTATGCACCTGGCCACCTCCCCCATCCTGTCAGAAGGAGCTTCGA GAATGGAATGCCAGCTGAAAAGGGGCTCTGTGGACAGGATGAGAGGCCTGGACCCCAGCACGCCAGCCCA AGTGATCGCTCCCAGCGAGACGCCGTCAAGCAGCTCTGTAGTAAAGAAGAGAAGAAAAAGGAGGAGAAAG TCACAGCTGGACAGCCTGAAGAGAGATGACAACATGAACACATCTGAGGATGAGGACATGTTCCCCATCG AGATGAGCTCGGATGAGGCCATGGAGCTGCTGGAGAGCAGCAGAACTCTTCCTAATGATATACCTCCATT CCAAGATGATATTCCTGAGGAAAACCTCTCCCTGGCTGTGATTTACCCTCAGTCAGCCTCATACCCTAAT TCGGATAGAGAGTGGTCACCCACTCCCAGTAGCCTGGTAGATTGCAAAAGGACTGCCCCTCATCTTGCAG TTGCGGCCGAGGGAGGTCTGTCTAGTTCTTGCCCTCCACAGTCTTCCCTGTTCCATCCTTCGGAAAGTCC TTCCGGTTCCCGACCTTCAACACCTAAAAGTGATTCAGAATTGGTCAGCAAGTCCACGGAAAGGACAGGG CAGAAGAACCCAGAAATGCTTTGGCTGTGGGGAGAGCTGCCGCAGGCTGCTAAGTCTTCTTCTCCACACA AGATGAAAGAGTCCAGCCCATTGAGCAGTAGAAAAATTTGTGATAAAAGTCACTTTCAGGCCATTCACAG CGAATCTTCAGACACTTTTAGTGACCAATCGCCAACTCTGGTCGGTGGGGCACTTTTGGACCAGAACAAG CCTCAGACAGAAATGCAGTTTGTGAATGAAGAAGACCTGGAGACCTTAGGAGCAGCAGCGCCACTCTTGC CCATGATCGAGGAGCTCAAACCCCCCTCTGCCAGTGTAGTCCAGACAGCAAACAAGACGGATTCTCCTTC CAGGAAAAGAGATAAACGAAGCCGACATCTTGGTGCTGACGGCGTCTACTTGGATGACCTCACAGACATG GATCCTGAAGTGGCGGCCCTGTATTTTCCCAAAAACGGAGATCCTTCCGGACTCGCAAAACATGCAAGCG ACAACGGAGCCCGGTCAGCCAACCAGTCCCCGCAGTCGGTGGGCAGCTCGGGCGTGGACAGTGGCGTGGA GAGCACCTCGGACGGGCTGAGGGACCTCCCTTCCATCGCCATCTCCCTCTGCGGGGGCCTCAGCGACCAC CGGGAGATCACGAAAGATGCATTCCTGGAGCAAGCTGTGTCATATCAACAGTTTGTGGACAACCCCGCTA TTATCGATGACCCCAATCTCGTGGTAAAGATTGGGAGTAAATATTATAACTGGACAACAGCAGCACCCCT CCTCCTGGCAATGCAGGCCTTCCAGAAACCTTTGCCAAAGGCCACTGTGGAATCTATCATGAGGGATAAA ATGCCCAAAAAGGGAGGAAGATGGTGGTTTTCATGGAGGGGAAGAAACACCACAATCAAGGAGGAAAGTA AGCCAGAGCAGTGCTTGGCTGGCAAGGCCCATAGCACCGGAGAGCAACCGCCGCAGCTCAGCTTGGCCAC CAGGGTAAAGCATGAATCATCCTCCAGTGATGAGGAGCGCGCAGCTGCCAAGCCATCAAACGCAGGCCAC CTCCCTCTTCTGCCTAATGTCAGCTACAAGAAGACTCTCCGGCTGACTTCCGAGCAGCTTAAAAGCTTGA AGTTGAAGAATGGCCCCAACGACGTGGTTTTCAGTGTCACCACGCAGTACCAAGGCACGTGCCGCTGTGA GGGCACCATCTATCTGTGGAACTGGGATGATAAAGTCATCATTTCTGATATTGATGGGACAATTACCAGA TCAGATACTCTTGGCCACATTTTGCCCACCCTTGGGAAGGATTGGACCCATCAGGGCATCGCTAAGCTGT ACCATAAAGTGAGCCAGAATGGATATAAATTTCTCTACTGTTCTGCCCGTGCCATCGGGATGGCGGACAT GACGCGGGGCTACCTGCACTGGGTCAACGAGAGGGGCACGGTGCTGCCCCAGGGGCCCCTGCTGCTGAGT CCCAGCAGCCTCTTCTCTGCCCTGCACAGAGAAGTGATTGAAAAGAAGCCAGAAAAGTTTAAAGTCCAGT GTTTGACAGACATCAAAAACCTGTTTTTCCCCAACACAGAACCCTTTTATGCTGCTTTTGGAAACCGACC AGCTGATGTGTATTCATACAAGCAAGTAGGAGTGTCTTTGAATAGAATATTTACCGTCAACCCTAAAGGA GAGCTGGTACAGGAACATGCAAAGACCAACATCTCTTCGTATGTGAGACTCTGTGAAGTAGTCGACCACG TTTTCCCGTTGCTGAAAAGAAGCCATTCTTCAGACTTTCCCTGTTCGGATACCTTCAGTAACTTCACCTT TTGGAGAGAGCCACTGCCACCTTTTGAAAACCAGGACATTCATTCTGCCTCAGCGTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001261428 |
ORF Size | 2928 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Reference Data | |
RefSeq | NM_001261428.1, NP_001248357.1 |
RefSeq Size | 5620 |
RefSeq ORF | 2928 |
Locus ID | 23175 |
Gene Summary | This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017] Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The encoded isoform (3) is longer compared to isoform 1. |
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