ARA9 (AIP) (NM_001302960) Human Untagged Clone

CAT#: SC335064

AIP (untagged) - Human aryl hydrocarbon receptor interacting protein (AIP), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AIP
• Synonyms: ARA9; FKBP16; FKBP37; PITA1; SMTPHN; XAP-2; XAP2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC335064 representing NM_001302960.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGCGGATATCATCGCAAGACTCCGGGAGGACGGGATCCAAAAACGTGTGATACAGGAAGGCCGAGGA
  GAGCTCCCGGACTTTCAAGATGGGACCAAGGCCACGTTCCACTACCGGACGCTGCACAGTGACGACGAG
  GGCACCGTGCTGGACGACAGCCGGGCTCGTGGCAAGCCCATGGAGCTCATCATTGGCAAGAAGTTCAAG
  CTGCCTGTGTGGGAGACCATCGTGTGCACCATGCGAGAAGGGGAGATTGCCCAGTTCCTCTGTGACATC
  AAGCATGTGGTCCTGTACCCGCTGGTGGCCAAGAGTCTCCGCAACATCGCGGTGGGCAAGGACCCCCTG
  GAGGGCCAGCGGCACTGCTGCGGTGTTGCACAGATGCGTGAACACAGCTCCCTGGGCCATGCTGACCTG
  GACGCCCTGCAGCAGAACCCCCAGCCCCTCATCTTCCACATGGAGATGCTGAAGGTGGAGAGCCCTGGC
  ACGTACCAGCAGGACCCATGGGCCATGACAGACGAAGAGAAGGCAAAGGCAGTGCCACTTATCCACCAG
  GAGGGCAACCGGTTGTACCGCGAGGGGCATGTGAAGGAGGCTGCTGCCAAGTACTACGATGCCATTGCC
  TGCCTCAAGAACCTGCAGATGAAGGAACAGCCTGGGTCCCCTGAATGGATCCAGCTGGACCAGCAGATC
  ACGCCGCTGCTGCTCAACTACTGCCAGTGCAAGCTGGTGGTCGAGGAGTACTACGAGGTGCTGGACCAC
  TGCTCTTCCATCCTCAACAAACAACGTCAAGGCCTACTTCAAGCGGGGCAAGGCCCACGCGGCCGTGTG
  GAATGCCCAGGAGGCCCAGGCTGA
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI Plasmid Map
• ACCN: NM_001302960
• Insert Size: 852 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001302960.1
• RefSeq Size: 1247 bp
• RefSeq ORF: 852 bp
• Locus ID: 9049
• UniProt ID: O00170
• Cytogenetics: 11q13.2
• Protein Families: Druggable Genome, Transcription Factors
• MW: 32 kDa
• Gene Summary: The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
  Transcript Variant: This variant (3) uses an alternate splice junction in the 3' end of the coding sequence compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1.