PMPCA (NM_001282946) Human Untagged Clone

CAT#: SC336047

PMPCA (untagged) - Human peptidase (mitochondrial processing) alpha (PMPCA), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PMPCA
• Synonyms: Alpha-MPP; CLA1; CPD3; INPP5E; P-55; SCAR2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282946, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGCGAAATACCTTAGTGGAATTGCTCACTTTTTGGAAAAATTGGCATTTTCGTCTACTGCTCGATT
  TGACAGCAAAGATGAAATTCTGCTTACGTTGGAAAAGCATGGGGGTATCTGTGACTGCCAGACATCAAGA
  CACCACCATGTATGCTGTGTCTGCTGATAGCAAAGGCTTGGACACGGTGGTTGCCTTACTGGCTGATGTG
  GTTCTGCAGCCCCGGCTAACAGATGAAGAAGTCGAGATGACGCGGATGGCGGTCCAGTTTGAGCTGGAGG
  ACCTGAACCTGCGGCCTGACCCAGAGCCACTTCTCACCGAGATGATTCATGAAGCGGCTTACAGGGAGAA
  CACAGTTGGCCTCCACCGTTTCTGCCCCACAGAAAACGTAGCAAAGATCAACCGAGAGGTGCTGCATTCC
  TACCTGAGGAACTACTACACTCCCGACCGCATGGTGCTGGCCGGCGTGGGCGTGGAGCACGAGCATCTGG
  TGGACTGTGCCCGGAAGTACCTCCTGGGGGTCCAGCCGGCCTGGGGGAGCGCAGAGGCCGTGGATATTGA
  CAGATCTGTGGCCCAGTACACTGGGGGGATTGCCAAGCTAGAAAGAGACATGTCCAATGTCAGCCTGGGC
  CCGACCCCCATCCCCGAGCTCACGCACATCATGGTTGGACTGGAGAGCTGCTCCTTCCTGGAGGAGGACT
  TCATCCCCTTTGCAGTGTTGAACATGATGATGGGCGGAGGTGGCTCCTTCTCGGCTGGTGGGCCCGGCAA
  GGGCATGTTCTCCAGGCTCTACCTCAACGTGCTCAACAGGCACCACTGGATGTATAACGCGACCTCCTAC
  CACCACAGCTACGAGGACACTGGCCTCCTTTGCATCCATGCCAGCGCCGACCCAAGACAGGTTCGAGAAA
  TGGTAGAAATCATCACAAAGGAGTTTATTTTAATGGGCGGAACCGTGGACACGGTGGAGCTGGAACGAGC
  CAAGACGCAGCTGACATCAATGCTCATGATGAACCTGGAATCCAGGCCTGTGATCTTCGAGGATGTGGGG
  AGGCAGGTGCTGGCCACTCGCTCCAGAAAGCTGCCGCACGAGCTGTGCACGCTCATCCGCAACGTGAAGC
  CGGAAGATGTGAAGAGAGTCGCTTCTAAGATGCTCCGAGGGAAGCCGGCAGTGGCCGCCCTGGGTGACCT
  GACTGACCTGCCCACGTATGAGCACATCCAGACCGCCCTGTCGAGTAAGGACGGGCGCCTGCCCAGGACG
  TACCGGCTCTTCCGGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282946
• ORF Size: 1278 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282946.1, NP_001269875.1
• RefSeq Size: 2180
• RefSeq ORF: 1278
• Locus ID: 23203
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (3) uses an alternate splice site in the 5' coding region which results in the use of an alternate start codon compared to variant 1. The encoded isoform (3) is shorter and has a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.