VPS45A (VPS45) (NM_001279355) Human Untagged Clone

CAT#: SC336179

VPS45 (untagged) - Human vacuolar protein sorting 45 homolog (S. cerevisiae) (VPS45), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VPS45
• Synonyms: H1; H1VPS45; SCN5; VPS45A; VPS45B; VPS54A; VSP45; VSP45A
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001279355, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAACGTGGTTTTTGCTGTGAAGCAGTACCCACATTTGTTTTCCCTCAATATTTTGGGTTGCTGCCAGG
  GTCGAAATTGGGATCCAGCCCAGCTATCTAGAACAACTCAAGGGCTTACAGCTCTCCTTTTATCTCTGAA
  GAAGTGTCCCATGATTCGTTATCAGCTCTCATCAGAGGCAGCAAAGAGACTTGCAGAGTGCGTTAAGCAA
  GTGATAACTAAAGAATATGAACTGTTTGAATTCCGTCGGACAGAGGTTCCTCCATTGCTCCTTATTTTAG
  ATCGCTGTGATGATGCCATCACCCCATTGCTAAACCAGTGGACATATCAGGCCATGGTCCACGAACTACT
  AGGCATAAACAACAATCGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGACTTAAGAGAAGTGGTC
  CTATCTGCTGAAAATGATGAATTCTATGCTAATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATA
  TAAAGAATCTCATGGAAGATTTTCAGAAGAAGAAACCAAAAGAACAGCAAAAACTAGAATCAATAGCAGA
  CATGAAGGCGTTTGTTGAGAATTATCCACAGTTCAAGAAAATGTCTGGGACTGTTTCAAAGCATGTGACA
  GTGGTTGGAGAACTGTCTCGATTGGTCAGTGAACGGAATCTGCTGGAGGTTTCAGAGGTTGAGCAAGAAC
  TGGCCTGTCAAAATGACCATTCTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAAAGTGAC
  AGAGTTTGATGCTGCCCGCCTGGTGATGCTTTATGCTTTACATTATGAGCGACACAGCAGCAATAGCCTG
  CCAGGACTAATGATGGACCTCAGGAATAAAGGTGTTTCTGAGAAGTATCGAAAGCTCGTGTCTGCAGTTG
  TTGAATATGGTGGTAAACGAGTCAGAGGAAGTGACCTCTTCAGCCCCAAAGATGCTGTGGCTATCACCAA
  ACAATTCCTCAAAGGACTGAAGGGAGTAGAAAATGTATATACACAGCATCAACCTTTCCTACATGAAACC
  CTGGATCATCTCATCAAAGGAAGGCTTAAGGAAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAG
  ACAGACCTCAGGATATCATTGTGTTTGTAATTGGAGGAGCCACCTATGAAGAGGCTCTAACAGTTTATAA
  CCTGAACCGCACCACTCCTGGAGTGAGGATTGTCCTGGGAGGCACCACAGTGCACAACACGAAAAGTTTC
  CTAGAGGAAGTTCTGGCTTCTGGACTGCACAGCCGAAGCAAGGAGAGCTCTCAAGTCACATCAAGGTCAG
  CGAGCAGAAGATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001279355
• ORF Size: 1344 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001279355.1, NP_001266284.1
• RefSeq Size: 2080
• RefSeq ORF: 1344
• Locus ID: 11311
• Protein Pathways: Endocytosis
• Gene Summary: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (4) lacks three consecutive exons and has an alternate splice junction in the 5' coding region, compared to variant 1. The resulting isoform (4) lacks an internal segment in the N-terminal region, compared to isoform 1.