Axotrophin (MARCH7) (NM_001282806) Human Untagged Clone

CAT#: SC337060

MARCH7 (untagged) - Human membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase (MARCH7), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MARCH7
• Synonyms: AXO; AXOT; MARCH-VII; RNF177
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282806, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGTCTAAACCTTCAAGGATTCCAAGAAGAATTTCTGTTCAACCTTCCAGCTCCTTAAGTGCTAGGA
  TGATGTCTGGAAGCAGAGGAAGTAGTTTAAATGATACCTATCACTCAAGAGACTCTTCATTTAGATTGGA
  TTCTGAATATCAGTCTACATCAGCATCAGCATCTGCGTCACCATTTCAATCTGCATGGTATAGTGAATCT
  GAGATAACTCAGGGAGCACGCTCAAGATCGCAGAACCAGCAACGGGATCATGATTCAAAAAGACCTAAAC
  TTTCCTGTACAAACTGTACTACCTCAGCTGGGAGAAATGTTGGAAATGGTTTAAACACATTATCAGATGT
  TCAAGACAGAGTTCCTTCATATTCACAAGGAGCAAGACCAAAAGAAAACTCAATGAGCACTTTACAGTTG
  AATACATCATCCACAAACCACCAATTGCCTTCTGAACATCAGACCATACTAAGTTCTAGGGACTCCAGAA
  ATTCTTTAAGATCAAATTTTTCTTCAAGAGAATCAGAATCTTCCCGAAGCAATACGCAGCCTGGATTTTC
  TTACAGTTCAAGTAGAGATGAAGCCCCAATCATAAGCAATTCAGAAAGGGTTGTTTCATCTCAAAGACCA
  TTTCAAGAATCTTCTGACAATGAAGGTAGGCGGACAACGAGGAGATTGCTGTCACGCATAGCTTCTAGCA
  TGTCATCTACTTTTTTTTCACGAAGATCTAGTCAGGATTCCTTGAATACAAGATCATTGAATTCTGAAAA
  TTCTTACGTTTCTCCAAGAATCTTGACAGCTTCACAGTCCCGTAGTAATGTACCATCAGCTTCTGAAGTT
  CCCGATAATAGGGCATCTGAAGCTTCTCAGGGATTTCGATTTCTTAGGCGAAGATGGGGTTTGTCATCTC
  TTAGCCACAATCATAGCTCTGAGTCAGATTCAGAAAATTTTAACCAAGAATCTGAAGGTAGAAATACAGG
  ACCATGGTTATCTTCCTCACTTAGAAATAGATGCACACCTTTGTTCTCTAGAAGGAGGCGAGAGGGAAGA
  GATGAATCTTCAAGGATACCTACCTCTGATACATCATCTAGATCTCATATTTTTAGAAGAGAATCAAATG
  AAGTGGTTCACCTTGAAGCACAGAATGATCCTCTTGGAGCTGCTGCCAACAGACCACAAGCATCTGCAGC
  ATCAAGCAGTGCCACAACAGGTGGCTCTACATCAGATTCGGCTCAAGGTGGAAGAAATACAGGAATATCA
  GGGATTCTTCCTGGTTCCTTATTCCGGTTTGCAGTCCCTCCAGCACTTGGGAGTAATTTGACCGACAATG
  TCATGATCACAGTAGATATTATTCCTTCAGGTTGGAATTCAGCTGATGGTAAAAGTGATAAAACTAAAAG
  TGCGCCTTCAAGAGATCCAGAAAGATTGCAGAAAATAAAAGAGAGCCTCCTTTTAGAGGACTCAGAAGAA
  GAAGAAGGTGACTTATGTAGAATTTGTCAAATGGCAGCTGCATCATCATCTAATTTGCTGATAGAGCCAT
  GCAAGTGCACAGGAAGTTTGCAGTATGTCCACCAAGACTGTATGAAAAAGTGGTTACAGGCCAAAATTAA
  CTCTGGTTCTTCATTAGAAGCTGTAACCACCTGTGAACTATGTAAAGAGAAGTTGGAGCTTAACCTGGAG
  GATTTTGATATTCATGAACTACATAGAGCTCATGCAAATGAACAAGCTGAGTATGAGTTTATCAGCTCTG
  GTCTCTACCTAGTGGTGTTATTGCACTTGTGCGAACAAAGCTTTTCTGATATGATGGGAAATACAAATGA
  ACCAAGCACACGTGTCCGACTTCAGAGGATGATTCCGAAGAAGACGGAGACCATAACAGGACATTTGATA
  TTGCCTAACTTCATATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282806
• ORF Size: 1908 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282806.1, NP_001269735.1
• RefSeq Size: 3319
• RefSeq ORF: 1908
• Locus ID: 64844
• Gene Summary: MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]). [supplied by OMIM, Mar 2010]
  Transcript Variant: This variant (3) differs in the 5' UTR, lacks an alternate in-frame exon in the 5' coding region, and lacks an exon that results in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a.