SP140 (NM_001278451) Human Untagged Clone

CAT#: SC337556

SP140 (untagged) - Human SP140 nuclear body protein (SP140), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SP140
• Synonyms: LYSP100; LYSP100-A; LYSP100-B
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001278451, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCAGCAGGGCCAGCAGGGGCAGATGGCAAGTGGAGACAGCAATCTCAACTTCAGGATGGTCGCAG
  AGATCCAGAACGTAGAGGGTCAGAACCTGCAGGAGCAGGTTTGCCCTGAGCCCATTTTCAGGTTCTTCAG
  AGAAAACAAGGTGGAGATTGCAAGTGCAATAACAAGGCCATTTCCTTTCCTTATGGGCCTCCGAGACCGC
  TCCTTCATCTCCGAGCAGATGTATGAACATTTTCAAGAAGCTTTTAGAAACCTGGTCCCAGTGACAAGAG
  TGATGTATTGTGTACTCAGTGAACTGGAGAAGACATTTGGCTGGTCACATCTGGAAGCATTGTTCAGCAG
  GATTAACCTGATGGCCTATCCTGATTTAAACGAGATTTACAGAAGCTTCCAGAATGTATGCTATGAACAC
  TCACCTCTCCAAATGAATAATGTAAACGATTTAGAAGATAGACCCAGATTACTACCATATGGTAAACAAG
  AGAACAGCAATGCCTGTCATGAAATGGATGATATAGCAGTGCCTCAGGAAGCCTTGAGCTCCTCGCCAAG
  GTGTGAGCCAGGTTTCTCTTCAGAGTCTTGTGAGCAGTTAGCTCTCCCAAAGGCTGGTGGAGGAGATGCT
  GAAGATGCACCCAGCCTACTACCAGGTGGGGGAGTGTCCTGTAAACTTGCTATACAAATAGATGAAGGAG
  AATCAGAAGAAATGCCCAAGTTACTGCCTTATGATACAGAAGTTCTAGAAAGCAACGGGATGATAGATGC
  GGCAAGGACATACAGCACAGCACCAGGGGAGAAACAGGGAGAGGAGGAAGGCAGGAACAGTCCCAGAAAA
  AGAAACCAAGACAAGGAGAAGTACCAAGAGAGTCCAGAGGGAAGAGACAAAGAGACCTTTGATCTAAAAA
  CTCCCCAAGTCACTAATGAAGGAGAACCAGAGAAGGGGCTCTGTCTACTACCAGGTGAAGGAGAAGAGGG
  CAGTGATGACTGTTCAGAAATGTGTGATGGAGAAGAGCCCCAGGAAGCCTCTAGCTCCCTAGCAAGATGT
  GGGTCAGTTTCTTGTTTATCTGCAGAGACCTTTGATCTAAAGACTCCCCAAGTCACTAATGAAGGAGAAC
  CAGAGAAGGAGCTCAGTCTACTACCAGGTGAAGGAGAAGTGTCTAGTGAACTAGAAAATCACCCAATGAA
  TGAAGAAGGAGAATCAGAAGAGCTTGCTTCTAGCCTGCTATATGATAATGTACCAGGAGCGGAGCAATCA
  GCATATGAAAATGAGAAGTGTTCCTGTGTCATGTGTTTCTCAGAAGAGGTGCCAGGAAGCCCAGAAGCAA
  GGACGGAAAGTGATCAAGCGTGTGGCACAATGGATACTGTGGATATTGCAAACAACTCCACTTTGGGAAA
  ACCCAAGAGGAAAAGAAGAAAAAAGAGGGGGCATGGCTGGAGCAGAATGAGAATGAGAAGGCAGGAAAAC
  AGCCAACAAAATGATAATAGCAAAGCCGACGGCCAGGTGGTCTCCAGTGAAAAGAAGGCGAACGTGAATC
  TGAAAGACCTTTCCAAGATTAGGGGGAGAAAGAGAGGCAAACCTGGAACCCGCTTCACTCAGAGTGACAG
  AGCTGCACAGAAAAGAGTCCGATCAAGAGCTTCAAGAAAGCACAAAGATGAAACTGTGGATTTTAAGGCT
  CCTTTGCTTCCAGTGACCTGTGGTGGGGTGAAGGGAATTTTACATAAGAAGAAATTGCAGCAAGGAATCT
  TGGTGAAGTGTATACAGACTGAGGATGGAAAATGGTTCACCCCCACGGAATTTGAAATCAAAGGAGGCCA
  TGCAAGATCAAAGAACTGGAGGCTGAGTGTGCGCTGTGGCGGGTGGCCCCTACGATGGCTGATGGAGAAT
  GGATTTCTGCCTGATCCTCCAAGAATACGTTACAGGAAAAAAAAGAGAATACTGAAGTCTCAAAACAATA
  GCTCAGTTGACCCTTGTATGAGAAACCTGGATGAGTGTGAGGTGTGCCGGGACGGAGGGGAGCTGTTCTG
  TTGCGACACTTGTTCAAGAGTCTTCCATGAGGACTGTCACATCCCGCCTGTGGAAGCTGAGAGGACCCCG
  TGGAATTGCATCTTCTGCAGGATGAAGGAGTCTCCGGGAAGCCAACAGTGTTGTCAGGAATCTGAGGTCC
  TGGAGAGGCAGATGTGTCCTGAGGAACAGTTGAAATGTGAGTTCCTCCTCTTGAAAGTCTATTGCTGTTC
  TGAGAGCTCCTTTTTTGCCAAGATTCCATACTATTATTATATTAGAGAGGCGTGTCAAGGCCTGAAGGAG
  CCCATGTGGTTGGATAAAATCAAGAAAAGGCTGAATGAGCACGGTTACCCCCAAGTGGAGGGGTTTGTAC
  AAGACATGCGCCTCATCTTCCAGAACCACAGGGCCTCTTACAAGTACAAGGATTTTGGCCAAATGGGATT
  TAGACTGGAGGCTGAGTTTGAGAAGAATTTCAAGGAAGTGTTTGCTATTCAGGAAACAAATGGGAACAAT
  TGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001278451
• ORF Size: 2523 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001278451.1, NP_001265380.1
• RefSeq Size: 3189
• RefSeq ORF: 2523
• Locus ID: 11262
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
  Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.