NMDAR2C (GRIN2C) (NM_001278553) Human Untagged Clone

CAT#: SC337610

GRIN2C (untagged) - Human glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), transcript variant 2


  "NM_001278553" in other vectors (1)

Reconstitution Protocol

USD 890.00

4 Weeks*

Size
    • 10 ug

Product Images

Other products for "GRIN2C"

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol GRIN2C
Synonyms GluN2C; NMDAR2C; NR2C
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>NCBI ORF sequence for NM_001278553, the custom clone sequence may differ by one or more nucleotides


ATGGGTGGGGCCCTGGGGCCGGCCCTGTTGCTCACCTCGCTCTTCGGTGCCTGGGCAGGGCTGGGTCCGG
GGCAGGGCGAGCAGGGCATGACGGTGGCCGTGGTGTTTAGCAGCTCAGGGCCGCCCCAGGCCCAGTTCCG
TGCCCGCCTCACCCCCCAGAGCTTCCTGGACCTACCCCTGGAGATCCAGCCGCTCACAGTTGGGGTCAAC
ACCACCAACCCCAGCAGCCTCCTCACCCAGATCTGCGGCCTCCTGGGTGCTGCCCACGTCCACGGCATTG
TCTTTGAGGACAACGTGGACACCGAGGCGGTGGCCCAGATCCTTGACTTCATCTCCTCCCAGACCCATGT
GCCCATCCTCAGCATCAGCGGAGGCTCTGCTGTGGTCCTCACCCCCAAGGAGCCGGGCTCCGCCTTCCTG
CAGCTGGGCGTGTCCCTGGAGCAGCAGCTGCAGGTGCTGTTCAAGGTGCTGGAAGAGTACGACTGGAGCG
CCTTCGCCGTCATCACCAGCCTGCACCCGGGCCACGCGCTCTTCCTGGAGGGCGTGCGCGCCGTCGCCGA
CGCCAGCCACGTGAGTTGGCGGCTGCTGGACGTGGTCACGCTGGAGCTGGGCCCGGGAGGGCCGCGCGCG
CGCACGCAGCGCCTGCTGCGCCAGCTCGACGCGCCCGTGTTTGTGGCCTACTGCTCGCGCGAGGAGGCCG
AGGTGCTCTTCGCCGAGGCGGCGCAGGCCGGTCTGGTGGGGCCCGGCCACGTGTGGCTGGTGCCCAACCT
GGCGCTGGGCAGCACCGATGCGCCCCCCGCCACCTTCCCCGTGGGCCTCATCAGCGTCGTCACCGAGAGC
TGGCGCCTCAGCCTGCGCCAGAAGGTGCGCGACGGCGTGGCCATTCTGGCCCTGGGCGCCCACAGCTACT
GGCGCCAGCATGGAACCCTGCCAGCCCCGGCCGGGGACTGCCGTGTTCACCCTGGGCCCGTCAGCCCTGC
CCGGGAGGCCTTCTACAGGCACCTACTGAATGTCACCTGGGAGGGCCGAGACTTCTCCTTCAGCCCTGGT
GGGTACCTGGTCCAGCCCACCATGGTGGTGATCGCCCTCAACCGGCACCGCCTCTGGGAGATGGTGGGGC
GCTGGGAGCATGGCGTCCTATACATGAAGTACCCCGTGTGGCCTCGCTACAGTGCCTCTCTGCAGCCTGT
GGTGGACAGTCGGCACCTGACGGTGGCCACGCTGGAAGAGCGGCCCTTTGTCATCGTGGAGAGCCCTGAC
CCTGGCACAGGAGGCTGTGTCCCCAACACCGTGCCCTGCCGCAGGCAGAGCAACCACACCTTCAGCAGCG
GGGACGTGGCCCCCTACACCAAGCTCTGCTGTAAGGGATTCTGCATCGACATCCTCAAGAAGCTGGCCAG
AGTGGTCAAATTCTCCTACGACCTGTACCTGGTGACCAACGGCAAGCATGGCAAGCGGGTGCGCGGCGTA
TGGAACGGCATGATTGGGGAGGTGTACTACAAGCGGGCAGACATGGCCATCGGCTCCCTCACCATCAATG
AGGAACGCTCCGAGATCGTAGACTTCTCTGTACCCTTTGTGGAGACGGGCATCAGTGTGATGGTGGCTCG
CAGCAATGGCACCGTCTCCCCCTCGGCCTTCTTGGAGCCATATAGCCCTGCAGTGTGGGTGATGATGTTT
GTCATGTGCCTCACTGTGGTGGCCATCACCGTCTTCATGTTCGAGTACTTCAGCCCTGTCAGCTACAACC
AGAACCTCACCAGAGGCAAGAAGTCCGGGGGCCCAGCTTTCACTATCGGCAAGTCCGTGTGGCTGCTGTG
GGCGCTGGTCTTCAACAACTCAGTGCCCATCGAGAACCCGCGGGGCACCACCAGCAAGATCATGGTTCTG
GTCTGGGCCTTCTTTGCTGTCATCTTCCTCGCCAGCTACACGGCCAACCTGGCCGCCTTCATGATCCAAG
AGCAATACATCGACACTGTGTCGGGCCTCAGTGACAAGAAGTTTCAGCGGCCTCAAGATCAGTACCCACC
TTTCCGCTTCGGCACGGTGCCCAACGGCAGCACGGAGCGGAACATCCGCAGTAACTACCGTGACATGCAC
ACCCACATGGTCAAGTTCAACCAGCGCTCGGTGGAGGACGCGCTCACCAGCCTCAAGATGGGGAAGCTGG
ATGCCTTCATCTATGATGCTGCTGTCCTCAACTACATGGCAGGCAAGGACGAGGGCTGCAAGCTGGTCAC
CATTGGGTCTGGCAAGGTCTTTGCTACCACTGGCTACGGCATCGCCATGCAGAAGGACTCCCACTGGAAG
CGGGCCATAGACCTGGCGCTCTTGCAGTTCCTGGGGGACGGAGAGACACAGAAACTGGAGACAGTGTGGC
TCTCAGGGATCTGCCAGAATGAGAAGAACGAGGTGATGAGCAGCAAGCTGGACATCGACAACATGGCAGG
CGTCTTCTACATGCTGCTGGTGGCCATGGGGCTGGCCCTGCTGGTCTTCGCCTGGGAGCACCTGGTCTAC
TGGAAGCTGCGCCACTCGGTGCCCAACTCATCCCAGCTGGACTTCCTGCTGGCTTTCAGCAGGGTGGGTG
CCCACCCCTCCCCACACAGGCCAAAGTTTTAA


Restriction Sites SgfI-MluI     
ACCN NM_001278553
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001278553.1, NP_001265482.1
RefSeq Size 3269 bp
RefSeq ORF 2622 bp
Locus ID 2905
Cytogenetics 17q25.1
Protein Families Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Long-term potentiation, Neuroactive ligand-receptor interaction
Gene Summary 'This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]'
Transcript Variant: This variant (2) differs in the 5' UTR, includes an alternate terminal 3' exon, and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR compared to variant 1. The encoded isoform (2) has a distinct and shorter C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.