VPS11 (NM_001290185) Human Untagged Clone

CAT#: SC337689

VPS11 (untagged) - Human vacuolar protein sorting 11 homolog (S. cerevisiae) (VPS11), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VPS11
• Synonyms: END1; HLD12; hVPS11; PEP5; RNF108
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001290185, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAATCTGTTTGTCGGAGGGGTCCGTGCCGCGCGCCTCTTTGGTTTAGCTGGTCATCCAGAGTTGTTC
  TGTGGTCTACGGGAAGAAAGAAGGAAGTCCATCTCCTAACTTGTTATCAACTGAGCAATCCTGGGAGGCT
  CCTTGACTACCCTGCACATATGGAAGGCCAGATCTGGTTCTTGCCACGTTCCCTACAGCTTACAGGCTTC
  CAAGCCTACAAACTACGGGTGACACACCTGTACCAACTGAAGCAGCACAATATTCTGGCATCTGTTGGAG
  AAGATGAAGAGGGCATCAACCCCTTGGTTAAGATCTGGAACCTGGAGAAGAGAGATGGTGGCAATCCACT
  CTGCACTCGAATCTTCCCTGCTATTCCAGGAACAGAGCCAACTGTTGTATCTTGTTTGACTGTCCATGAA
  AATCTCAACTTTATGGCCATTGGTTTCACAGATGGCAGTGTTACATTGAACAAAGGAGACATCACCCGGG
  ACCGGCATAGCAAGACCCAGATTTTGCACAAGGGCAACTATCCTGTAACTGGATTGGCCTTTCGCCAAGC
  AGGAAAGACCACTCACTTGTTTGTTGTGACAACAGAGAACGTCCAGTCCTATATAGTTTCTGGAAAAGAC
  TACCCTCGCGTGGAGTTGGACACCCATGGTTGTGGCCTGCGCTGCTCAGCCCTAAGTGACCCTTCTCAGG
  ACCTGCAGTTCATTGTGGCCGGGGATGAGTGTGTCTACTTGTACCAGCCTGATGAACGTGGGCCCTGCTT
  CGCCTTTGAGGGCCATAAGCTCATTGCCCACTGGTTTAGAGGCTACCTTATCATTGTCTCCCGTGACCGG
  AAGGTTTCTCCCAAGTCAGAGTTTACCAGCAGGGATTCACAGAGCTCCGACAAGCAGATTCTAAACATCT
  ATGACCTGTGCAACAAGTTCATAGCCTATAGCACCGTCTTTGAGGATGTAGTGGATGTGCTTGCTGAGTG
  GGGCTCCCTGTACGTGCTGACGCGGGATGGGCGGGTCCACGCACTGCAGGAGAAGGACACACAGACCAAA
  CTGGAGATGCTGTTTAAGAAGAACCTATTTGAGATGGCGATTAACCTTGCCAAGAGCCAGCATCTGGACA
  GTGATGGGCTGGCCCAGATTTTCATGCAGTATGGAGACCATCTCTACAGCAAGGGCAACCACGATGGGGC
  TGTCCAGCAATATATCCGAACCATTGGAAAGTTGGAGCCATCCTACGTGATCCGCAAGTTTCTGGATGCC
  CAGCGCATTCACAACCTGACTGCCTACCTGCAGACCCTGCACCGACAATCCCTGGCCAATGCCGACCATA
  CCACCCTGCTCCTCAACTGCTATACCAAGCTCAAGGACAGCTCGAAGCTGGAGGAGTTCATCAAGAAAAA
  GAGTGAGAGTGAAGTCCACTTTGATGTGGAGACAGCCATCAAGGTCCTCCGGCAGGCTGGCTACTACTCC
  CATGCCCTGTATCTGGCGGAGAACCATGCACATCATGAGTGGTACCTGAAGATCCAGCTAGAAGACATTA
  AGAATTATCAGGAAGCCCTTCGATACATCGGCAAGCTGCCTTTTGAGCAGGCAGAGAGCAACATGAAGCG
  CTACGGCAAGATCCTCATGCACCACATACCAGAGCAGACAACTCAGTTGCTGAAGGGACTTTGTACTGAT
  TATCGGCCCAGCCTCGAAGGCCGCAGCGATAGGGAGGCCCCAGGCTGCAGGGCCAACTCTGAGGAGTTCA
  TCCCCATCTTTGCCAATAACCCGCGAGAGCTGAAAGCCTTCCTAGAGCACATGAGTGAAGTGCAGCCAGA
  CTCACCCCAGGGGATCTACGACACACTCCTTGAGCTGCGACTGCAGAACTGGGCCCACGAGAAGGATCCA
  CAGGTCAAAGAGAAGCTTCACGCAGAGGCCATTTCCCTGCTGAAGAGTGGTCGCTTCTGCGACGTCTTTG
  ACAAGGCCCTGGTCCTGTGCCAGATGCACGACTTCCAGGATGGTGTCCTTTACCTTTATGAGCAGGGGAA
  GCTGTTCCAGCAGATCATGCACTACCACATGCAGCACGAGCAGTACCGGCAGGTCATCAGCGTGTGTGAG
  CGCCATGGGGAGCAGGACCCCTCCTTGTGGGAGCAGGCCCTCAGCTACTTCGCTCGCAAGGAGGAGGACT
  GCAAGGAGTATGTGGCAGCTGTCCTCAAGCATATCGAGAACAAGAACCTCATGCCACCTCTTCTAGTGGT
  GCAGACCCTGGCCCACAACTCCACAGCCACACTCTCCGTCATCAGGGACTACCTGGTCCAAAAACTACAG
  AAACAGAGCCAGCAGATTGCACAGGATGAGCTGCGGGTGCGGCGGTACCGAGAGGAGACCACCCGTATCC
  GCCAGGAGATCCAAGAGCTCAAGGCCAGTCCTAAGATTTTCCAAAAGACCAAGTGCAGCATCTGTAACAG
  TGCCTTGGAGTTGCCCTCAGTCCACTTCCTGTGTGGCCACTCCTTCCACCAACACTGCTTTGAGAGTTAC
  TCGGAAAGTGATGCTGACTGCCCCACCTGCCTCCCTGAAAACCGGAAGGTCATGGATATGATCCGGGCCC
  AGGAACAGAAACGAGATCTCCATGATCAATTCCAGCATCAGCTCAAGTGCTCCAATGACAGCTTTTCTGT
  GATTGCTGACTACTTTGGCAGAGGTGTTTTCAACAAATTGACTCTGCTGACCGACCCTCCCACAGCCAGA
  CTGACCTCCAGCCTGGAGGCTGGGCTGCAACGCGACCTACTCATGCACTCCAGGAGGGGCACTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001290185
• ORF Size: 2796 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001290185.1, NP_001277114.1
• RefSeq Size: 3486
• RefSeq ORF: 2796
• Locus ID: 55823
• Protein Families: Druggable Genome
• Gene Summary: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
  Transcript Variant: This variant (2) differs in its 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1.