Hephaestin (HEPH) (NM_001282141) Human Untagged Clone

CAT#: SC337728

HEPH (untagged) - Human hephaestin (HEPH), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HEPH
• Synonyms: CPL
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282141, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGGGCCATGGAGTCAGGCCACCTCCTCTGGGCTCTGCTGTTCATGCAGTCCTTGTGGCCTCAACTGA
  CTGATGGAGCCACTCGAGTCTACTACCTGGGCATCCGGGATGTGCAGTGGAACTATGCTCCCAAGGGAAG
  AAATGTCATCACGAACCAGCCTCTGGACAGTGACATAGTGGCTTCCAGCTTCTTAAAGTCTGACAAGAAC
  CGGATAGGGGGAACCTACAAGAAGACCATCTATAAAGAATACAAGGATGACTCATACACAGATGAAGTGG
  CCCAGCCTGCCTGGTTGGGCTTCCTGGGGCCAGTGTTGCAGGCTGAAGTGGGGGATGTCATTCTTATTCA
  CCTGAAGAATTTTGCCACTCGTCCCTATACCATCCACCCTCATGGTGTCTTCTACGAGAAGGACTCTGAA
  GGTTCCCTATACCCAGATGGCTCCTCTGGGCCACTGAAAGCTGATGACTCTGTTCCCCCGGGGGGCAGCC
  ATATCTACAACTGGACCATTCCAGAAGGCCATGCACCCACCGATGCTGACCCAGCGTGCCTCACCTGGAT
  CTACCATTCTCATGTAGATGCTCCACGAGACATTGCAACTGGCCTAATTGGGCCTCTCATCACCTGTAAA
  AGAGGAGCCCTGGATGGGAACTCCCCTCCTCAACGCCAGGATGTAGACCATGATTTCTTCCTCCTCTTCA
  GTGTGGTAGATGAGAACCTCAGCTGGCATCTCAATGAGAACATTGCCACTTACTGCTCAGATCCTGCTTC
  AGTGGACAAAGAAGATGAGACATTTCAGGAGAGCAATAGGATGCATGCAATCAATGGCTTTGTTTTTGGG
  AATTTACCTGAGCTGAACATGTGTGCACAGAAACGTGTGGCCTGGCACTTGTTTGGCATGGGCAATGAAA
  TTGATGTCCACACAGCATTTTTCCATGGACAGATGCTGACTACCCGTGGACACCACACTGATGTGGCTAA
  CATCTTTCCAGCCACCTTTGTGACTGCTGAGATGGTGCCCTGGGAACCTGGTACCTGGTTAATTAGCTGC
  CAAGTGAACAGTCACTTTCGAGATGGCATGCAGGCACTCTACAAGGTCAAGTCTTGCTCCATGGCCCCTC
  CTGTGGACCTGCTCACAGGCAAAGTTCGACAGTACTTCATTGAGGCCCATGAGATTCAATGGGACTATGG
  CCCGATGGGGCATGATGGGAGTACTGGGAAGAATTTGAGAGAGCCAGGCAGTATCTCAGATAAGTTTTTC
  CAGAAGAGCTCCAGCCGAATTGGGGGCACTTACTGGAAAGTGCGATATGAAGCCTTTCAAGATGAGACAT
  TCCAAGAGAAGATGCATTTGGAGGAAGATAGGCATCTTGGAATCCTGGGGCCAGTGATCCGGGCTGAGGT
  GGGTGACACCATTCAGGTGGTCTTCTACAACCGTGCCTCCCAGCCATTCAGCATGCAGCCCCATGGGGTC
  TTTTATGAGAAAGACTATGAAGGCACTGTGTACAATGATGGGACATTTGAGATTTATTGCCAGGCAGGCA
  GCCATCGAGAAGCAGGGATGAGGGCAATCTATAATGTCTCCCAGTGTCCTGGCCACCAAGCCACCCCTCG
  CCAACGCTACCAAGCTGCAAGAATCTACTATATCATGGCAGAAGAAGTAGAGTGGGACTATTGCCCTGAC
  CGGAGCTGGGAACGGGAATGGCACAACCAGTCTGAGAAGGACAGTTATGGTTACATTTTCCTGAGCAACA
  AGGATGGGCTCCTGGGTTCCAGATACAAGAAAGCTGTATTCAGGGAATACACTGATGGTACATTCAGGAT
  CCCTCGGCCAAGGACTGGACCAGAAGAACACTTGGGAATCTTGGGTCCACTTATCAAAGGTGAAGTTGGT
  GATATCCTGACTGTGGTATTCAAGAATAATGCCAGCCGCCCCTACTCTGTGCATGCTCATGGAGTGCTAG
  AATCTACTACTGTCTGGCCACTGGCTGCTGAGCCTGGTGAGGTGGTCACTTATCAGTGGAACATCCCAGA
  GAGGTCTGGCCCTGGGCCCAATGACTCTGCTTGTGTTTCCTGGATCTATTATTCTGCAGTGGATCCCATC
  AAGGACATGTATAGTGGCCTGGTGGGGCCCTTGGCTATCTGCCAAAAGGGCATCCTGGAGCCCCATGGAG
  GACGGAGTGACATGGATCGGGAATTTGCATTGTTGTTCTTGATTTTTGATGAAAATAAGTCTTGGTATTT
  GGAGGAAAATGTGGCAACCCATGGGTCCCAGGATCCAGGCAGTATTAACCTACAGGATGAAACTTTCTTG
  GAGAGCAATAAAATGCATGCAATCAATGGGAAACTCTATGCCAACCTTAGGGGTCTTACCATGTACCAAG
  GAGAACGAGTGGCCTGGTACATGCTGGCCATGGGCCAAGATGTGGATCTACACACCATCCACTTTCATGC
  AGAGAGCTTCCTCTATCGGAATGGCGAGAACTACCGGGCAGATGTGGTGGATCTGTTCCCAGGGACTTTT
  GAGGTTGTGGAGATGGTGGCCAGCAACCCTGGGACATGGCTGATGCACTGCCATGTGACTGACCATGTCC
  ATGCTGGCATGGAGACCCTCTTCACTGTTTTTTCTCGAACAGAACACTTAAGCCCTCTCACCGTCATCAC
  CAAAGAGACTGAAAAAGCAGTGCCCCCCAGAGACATTGAAGAAGGCAATGTGAAGATGCTGGGCATGCAG
  ATCCCCATAAAGAATGTTGAGATGCTGGCCTCTGTTTTGGTTGCCATTAGTGTCACCCTTCTGCTCGTTG
  TTCTGGCTCTTGGTGGAGTGGTTTGGTACCAACATCGACAGAGAAAGCTACGACGCAATAGGAGGTCCAT
  CCTGGATGACAGCTTCAAGCTTCTGTCTTTCAAACAGTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282141
• ORF Size: 2910 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282141.1, NP_001269070.1
• RefSeq Size: 3888
• RefSeq ORF: 2910
• Locus ID: 9843
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a member of the multicopper oxidase protein family. The encoded protein is involved in the transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system, and may be involved in copper transport and homeostasis. In mouse, defects in this gene can lead to severe microcytic anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (4) contains an alternate 5'-most exon, lacks three consecutive exons in the central coding region, and initiates translation at a downstream start codon, compared to variant 1. The resulting isoform (d) is shorter, compared to isoform a.