Apln (NM_013912) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR200116L4V
- LentiORF®
Lenti ORF particles, Apln (GFP-tagged) - Mouse apelin (Apln), 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Apln |
Synonyms | 6030430G11Rik; Apel |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_013912 |
ORF Size | 234 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR200116).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_013912.3, NP_038940.1 |
RefSeq Size | 3148 |
RefSeq ORF | 234 |
Locus ID | 30878 |
Gene Summary | This gene encodes the neuropeptide Apelin, an endogenous ligand of the G protein-coupled receptor APJ. This gene is highly expressed in the central nervous system and peripheral tissues and the encoded preproprotein undergoes proteolytic processing to generate mature peptides of different sizes that are secreted into the plasma. These peptides play important roles in a broad range of physiological processes such as cardiac contractility, blood pressure, blood vessel growth, appetite and drink behavior, and pituitary hormone secretion. Mice lacking the encoded protein develop progressive heart failure and exhibit a shorter bleeding time, prothrombotic profile and increased bone mass. [provided by RefSeq, Jul 2016] |
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