Casp4 (NM_007609) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR205770L4V

  • LentiORF®

Lenti ORF particles, Casp4 (GFP-tagged) - Mouse caspase 4, apoptosis-related cysteine peptidase (Casp4), 200ul, >10^7 TU/mL

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USD 700.00

3 Weeks*

Size
    • 200 ul
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Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag mGFP
Symbol Casp4
Synonyms CASP-4; CASP-11; Casp11; Caspl; ich-3
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_007609
ORF Size 1119 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR205770).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_007609.1, NP_031635.1
RefSeq Size 1350
RefSeq ORF 1122
Locus ID 12363
Gene Summary This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015]

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