Psap (NM_001146123) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR227327L4V

  • LentiORF®

Lenti ORF particles, Psap (GFP-tagged) - Mouse prosaposin (Psap), transcript variant 5, 200ul, >10^7 TU/mL


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USD 970.00

7 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag mGFP
Symbol Psap
Synonyms AI037048; SGP-1
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001146123
ORF Size 1635 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR227327).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001146123.1, NP_001139595.1
RefSeq Size 2640
RefSeq ORF 1638
Locus ID 19156
Gene Summary This gene encodes a multifunctional glycoprotein that plays a role in the intracellular metabolism of various sphingolipids or secreted into the plasma, milk or cerebrospinal fluid. The encoded protein undergoes proteolytic processing to generate four different polypeptides known as saposin A, B, C or D, that are required for the hydrolysis of certain sphingolipids by lysosomal hydrolases. Alternately, the encoded protein is secreted into body fluids where it exhibits neurotrophic and myelinotrophic activities. A complete lack of the encoded protein is fatal to mice either at the neonatal stage or within the first month due to severe leukodystrophy and sphingolipid accumulation. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate the mature saposins. [provided by RefSeq, Sep 2015]

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