IRF6 (NM_006147) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201579L2V

Lenti ORF particles, IRF6 (mGFP-tagged) - Human interferon regulatory factor 6 (IRF6), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: IRF6
• Synonyms: LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
• Vector: pLenti-C-mGFP
• ACCN: NM_006147
• ORF Size: 1401 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201579).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006147.2, NP_006138.1
• RefSeq Size: 4505 bp
• RefSeq ORF: 1404 bp
• Locus ID: 3664
• Cytogenetics: 1q32.2
• Domains: IRF
• Protein Families: ES Cell Differentiation/IPS, Transcription Factors
• MW: 53.1 kDa
• Gene Summary: 'This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011]'